N/A N=14 Agonist-Antagonist Myoneural Interface for Functional Limb Restoration After Transtibial Amputation
Amputation
Primary: Stability of Joint Position Control in Free Space — 4; 3.1 Distinct synergy activations
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=10 Functional Outcomes in Dysvascular Transfemoral Amputees
Transfemoral Amputation · Unilateral Traumatic Amputation of Leg at or Above Knee
Primary: Change in Community Physical Activity as Measured by GPS — 1749; 1625; 1257 Steps per day
N/A N=50 Forensic-medical Aspects of Lower Limb Prosthetics: An Observational Study
Amputation
Primary: Questionnaire: Trinity Amputation Prosthesis Experience Scale (TAPES) — 57; 8; 40 units on a scale
N/A N=20 Functional Electrical Stimulation Use in Trans-tibial Amputations
Traumatic Amputation of Lower Extremity
Primary: Change in Knee Extension Isometric Strength (Peak Torque) Using the Biodex Measurement System — -0.1; 2.2 Nm/kg — p=0.768
N/A N=12 Optimizing Prosthetic and Bicycle Fit for Veterans With Transtibial Amputations
Amputation
Primary: Mechanical Crank Power Output — 0.59; 0.99; 0.60; 0.97 W/kg
N/A N=18 Evidence Based Amputee Rehabilitation (EBAR) Program
Amputation Stumps · Diabetes Mellitus
Primary: Amputee Mobility Predictor — 36.4; 35.3; 41.7; 35.6 Points
N/A N=35 Assessment of Disability Compensation With the C-LEG COMPACT 2 Knee (Ref. 3C60 et 3C60=ST)
Amputation of Hip and Thigh, Level Unspecified
Primary: Timed Get Up and Go (TGUG) — 24.8; 21.6 seconds
Phase 1 N=6 Use of Autologous Concentrated Bone Marrow Aspirate in Preventing Wound Complications in Below Knee Amputation (BKA)
Peripheral Artery Disease · Vascular Disease · Critical Limb Ischemia
Primary: Number of Participants With Treatment-related Adverse Events Occurring During the Enrollment Period as Assessed by the Investigator Using the CTCAE 4.0 Scale. — 2; 0…
N/A N=6 Biomechanical Evaluation of a Novel, Compliant Low Profile Prosthetic Foot
Amputation
Primary: Total Energy Stored (TES) — 20.1; 13.3 Joules
N/A N=68 Bioimpedance as a Diagnostic Tool for Assessing the Need for Socket Modification in Transtibial Amputees
Transtibial Amputee
Primary: Number of Participants With Significant Increases in Socket Comfort Score (SCS) — 5; 6; 4 participants
N/A N=11 Prosthetic Components and Stability in Amputee Gait
Diabetes Mellitus · Leg Injuries · Traumatic Amputation
Primary: Local Dynamic Stability (Hip During Straight Walking) — .74; .74 dimensionless — p=>0.99
N/A N=10 Biomechanical Assessment of Gait in Lower-Extremity-Amputees
Prosthesis User
Primary: Overall Asymmetry Index — 0.064; 0.352; 0.541; 1.481 unit-less index (0 = perfect symmetry)
N/A N=15 ICG Fluorescence Imaging in Lower Extremity Amputation Patients
Trauma Injury
Primary: Total Bone Blood Flow (TBBF)-Post Osteotomy — 4.9 mL/min/100g
N/A N=11 Pivot-Flex Foot: Optimal Coupling Ratio Between Transverse and Sagittal-plane Motions Using a Torsionally Adaptive Prosthesis for Individuals With Lower Limb Amputation
Lower Extremity Amputation
Primary: Peak Transverse-plane Prosthetic Socket Torque Normalized to Body Mass — 0.299; 0.340; 0.306; 0.292 Nm/kg — p=0.029
N/A N=25 Comparative Outcomes Assessment of the C-Leg With a New Knee Prosthesis
Other and Unspecified Complications of Amputation Stump
Primary: 75 Meter Self Selected Walking Test — 65.1; 64.0; 54.0 seconds
N/A N=56 AMPLEX Ankle Fusion and Hindfoot
Arthrodesis Surgery Involving the Hindfoot or Ankle
Primary: Proportion of Subjects Who Met All Five Criteria for Subject Performance Composite (SPC) Endpoint — 79.5; 35.3 percentage of subjects
N/A N=6 Basic Mobility and Balance Performance of Low Active Transfemoral Prosthesis Users With a Powered Prosthetic Knee
Prosthesis User · Amputation
Primary: Timed Up and Go Test (TUG Test) — 13.3; 16.8 seconds
Phase 3 N=10 Southern Bone & Joint Study - Brimless Sockets
Socket Designs of Transfemoral Amputees.
Primary: Gait
N/A N=13 Compression Nail for Tibiocalcaneal Arthrodesis
Subtalar Arthritis · Ankle Arthritis
Primary: Pain Assessment — 52.73; 33.00; 17.00; 21.25 score on a scale
N/A N=21 Internal Brace Augmented Anterior Inferior Tibiofibular Ligament Repair: Post-operative Syndesmotic Volumes.
Syndesmotic Injuries · Ligament Rupture · Bimalleolar Fractures
Primary: Syndesmotic Volumetric Ratio — 1.2; 1.1 Volumetric Ratio
N/A N=13 C-Leg 3 and C-Leg 4 Study in Transfemoral Amputees
Lower Limb Amputation Above Knee (Injury)
Primary: Change in 6 Minute Gait Test — 380.4; 380.4; 35.9; 26.7 meters — p=0.01
Phase 4 N=58 Reducing Hemarthrosis in Tibial Tubercle Osteotomy by the Administration of Intravenous Tranexamic Acid
Tibial Tubercle Osteotomy
Primary: Perioperative Blood Loss — 67.8; 56.15 mL
N/A N=99 A Multicenter Randomized Trial Comparing IM Nails and Plate Fixation in Proximal Tibial Fractures
Tibial Fractures
Primary: Participants' Quality of Life at 3 Months — 0.60; 0.59 score on a scale
Phase 4 N=100 Efficacy of Tranexamic Acid in Foot and Ankle Surgeries
Foot and Ankle Surgeries · Bunion
Primary: Total Estimated Blood Loss — 40.41; 18.75 ml
N/A N=71 Immediate Fit Using Innovative Technology Transtibial & Transfemoral Prosthesis
Amputation
Primary: Prosthetic Comfort and Utility Questionnaire (Version 1) — 25.52; 29.33 score on a scale
N/A N=358 Study of IN.PACT Amphirion™ Drug Eluting Balloon vs. Standard PTA for the Treatment of Below the Knee Critical Limb Ischemia
Critical Lower Limb Ischemia
Primary: Late Lumen Loss (LLL) of the Target Lesion by Quantitative Vascular Angiography (QVA) — 0.605; 0.616 mm
Phase 3 N=7 Metabolic Cost Savings for Transtibial Amputees Wearing the Controlled Energy Storage and Return (CESR) Foot
Transtibial Amputation
Primary: Metabolic Oxygen Consumption During Ambulation — 3.45; 3.13; 2.97 Watts per kilogram
Phase 4 N=36 Topical (Intra-Articular) Tranexamic Acid and Transfusion Rates Following Hip Hemiarthroplasty
Femoral Neck Fractures
Primary: Number of Participants Who Needed Transfusions — 0; 5 Participants
Phase 2 N=101 Topical Tranexamic Acid and Acute Blood Loss in Total Knee Arthroplasty
Acute Blood Loss Anemia · Osteoarthritis, Knee
Primary: Blood Loss — 1293.1; 940.2 mL
N/A N=36 Evaluation of a Modified Running-specific Prosthetic Foot
Transtibial Amputation
Primary: Metabolic Oxygen Consumption (VO2), Participants With Unilateral Amputation — 1041.1; 1077.4; 1210.9; 1253.5 ml/min — p=.18