N/A N=1,957 Moderate Acute Malnutrition (MAM) and Severe Acute Malnutrition (SAM) in Sierra Leone
Malnutrition
Primary: Recovery Under the Integrated Program and the Standard Protocol — 910; 682 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=132 Management of Severe Acute Malnutrition in SCD, in Northern Nigeria
Sickle Cell Anemia · Severe Acute Malnutrition
Primary: Enrollment Rate at the End of the 6-month Recruitment Period — 111; 22; 110; 22 participants
N/A N=2,712 Effectiveness Comparison of Three Supplementary Foods in the Treatment of Moderate Acute Malnutrition
Malnutrition
Primary: Number of Participants With Nutritional Recovery — 763; 795; 807 participants
Phase 3 N=301 Azithromycin for Uncomplicated Severe Acute Malnutrition in Burkina Faso (Pilot)
Uncomplicated Severe Acute Malnutrition
Primary: Weight Gain — 1.8; 2.0 g/kg/day
Phase 3 N=5,449 Complementary Food Supplements for Reducing Childhood Undernutrition
Stunting · Wasting
Primary: Stunting in Children at 18 mo — 559; 542; 341; 300 Participants
N/A N=2,259 Whey Permeate Study
Malnutrition
Primary: Recovery From Moderate Acute Malnutrition (MAM) — 960; 874 Participants
N/A N=324 Promoting Physical Growth and Positive Development in Severely Stunted Guatemalan Children
Malnutrition · Developmental Disabilities
Primary: Change in Height/Length for Age Z Score — -0.02; 0.05 Z scores
Phase 4 N=52 IMPAACT P1092: Steady State PK in Malnourished HIV Infected Children
HIV Positive · Malnourished
Primary: Grade 3 or Higher Adverse Events Through 24 Weeks — 13; 10 Participants — p=0.40
N/A N=1,087 Mobile Messaging for Improved Nutrition
Diet, Healthy · Anemia
Primary: Number of Children Who Consume a Minimum Acceptable Diet — 67; 92; 138; 191 Participants — p=0.145
Phase 3 N=44,567 Antenatal Micronutrient Supplementation and Infant Survival
Infant Mortality · Preterm Birth · Low Birth Weight
Primary: Infant Mortality Through 6 mo of Age — 764; 741 participants — p=0.36
N/A N=600 Evaluating Oral Nutritional Supplements on Children's Nutritional Status and Digestive Health in Vietnam.
Undernutrition · Wasting · Malnourished
Primary: Improvement of Digestive Disorders and Anorexia Nervosa — 219; 212; 175; 155 participants
N/A N=151 Effects of a Protein Calorie Supplement in HIV-infected Women With Tuberculosis
HIV · Tuberculosis
Primary: Change in CD4 Count — 215; 174 increase in CD4 cells/mm^3
N/A N=1,059 Enhanced Protein-Energy Provision Via the Enteral Route in Critically Ill Patients
Critically Ill
Primary: Percentage of Prescribed Calories From Energy — 32; 34.2; 43.6; 33.6 percentage of prescription
N/A N=183 Pediatric Urgent Start of Highly Active Antiretroviral Treatment (HAART)
Human Immunodeficiency Virus · Immune Reconstitution Inflammatory Syndrome
Primary: All-cause Mortality — 21; 18 participants
N/A N=2,221 Kangaroo Mother Care Before Stabilisation Amongst Low Birth Weight Neonates in Africa
Kangaroo Mother Care · Preterm Infant · Death; Neonatal
Primary: Mortality Within 7 Days — 81; 83 Participants
N/A N=34 COPD: Oral Nutrition Supplements vs. Energy- and Protein Dense in Between Meal Snacks.
Malnutrition
Primary: Weight Changes — 2.3; 4.4 kg
N/A N=96 DarDar Nutrition Study in HIV Breastfeeding Women
Low Birth Weight
Primary: Infant Weight — 6.92; 7.32 kg
N/A N=40 Personalized Nutrition Delivery to Improve Resilience in Older Adult Trauma Patients
Trauma · Critical Illness
Primary: Number of Patients Recruited — 28; 12 Participants
Phase 3 N=143 Micronutrient Sprinkles in a Daycare Center
Diarrhea · Respiratory Infection
Primary: Proportion of Children of Diarrhea Episodes — 19.1; 14.7 percentage of participants
N/A N=991 ACTION PAC: Adolescents Committed to Improvement of Nutrition & Physical Activity
Overweight · Obesity
Primary: Number and Proportion of Participants With Baseline BMI <85th Percentile Who Developed Overweight or Obesity by the End of the Study — 22; 12 Participants
N/A N=610 Monitoring and Evaluation of Micronutrients (Sprinkles) Project
Anemia
Primary: Number of Participants With Anemia — 185; 172; 139; 191 participants — p=0.32
Phase 3 N=396 Next Generation ORS: Comparing ORS With Calcium vs Standard ORS in Reducing Severity of Acute Watery Diarrhea
Diarrhea · Cholera
Primary: Stool Output — 4769; 4742; 1688; 1704 gram — p=0.9941
N/A N=2,288 Alive & Thrive Evaluation in Burkina Faso
Breast Feeding · Breast Feeding, Exclusive
Primary: Exclusive Breastfeeding on the Day Preceding the Interview as Assessed by Cross Sectional Survey — 0.933; 0.512 percentage of exclusive breastfeeding
Phase 3 N=5,920 Seasonal Malaria Vaccination (RTS,S/AS01) and Seasonal Malaria Chemoprevention (SP/AQ)
Malaria,Falciparum · Children, Only
Primary: Incidence of Clinical Episodes of Malaria — 304.8; 278.2; 113.3 No. of events/1000 person years at risk
N/A N=103,117 Trial of the Use of Antenatal Corticosteroids in Developing Countries
Preterm Birth
Primary: Neonatal Mortality Rate at 28 Days in <5th Percentile Birth Weight Infants (as a Proxy Measure for Prematurity) — 566; 524 Participants — p=0.65
N/A N=355 The Impact of Legumes vs Corn-soy Flour on Environmental Enteric Dysfunction in Rural Malawian Children 6-11 Months
Enteropathy
Primary: Change in Length-for-age z Score Over 6 Months From Enrollment to End of Study. — -0.14; -0.27; -0.27 z-score
N/A N=715 Impact of the "Ten Steps for Healthy Feeding of Children Younger Than Two Years" in Health Centers
Feeding and Eating Disorders of Childhood
Primary: Exclusive Breastfeeding at Four Months of Age — 140; 104 Participants
N/A N=574 Healthy Mothers-Healthy Children Nutrition
Overweight and Obesity · Adiposity · Nutrient; Excess
Primary: Change in Mother's Height From Baseline (Time 1) to Time 2 — -0.00977; 0.000505 Centimeters
N/A N=59 Intervening in Food Insecurity to Reduce and Mitigate (InFoRM) Childhood Obesity
Pediatric Obesity · Nutrition Disorders · Overnutrition, Child
Primary: Study Feasibility: Recruitment — 59; 10 Participants
N/A N=100 Impact of Oral Nutritional Supplements on Patients Undergoing Haematopoietic Stem Cell Transplantation
Haematological Malignancy
Primary: The Between-group Change for Body Weight — -4.0; -3.4 kilogram — p=0.24