Clinical Trial Search

Primary: Number of Participants With Adequate Exposure and Access to Oropharyngeal and Hypopharyngeal Head and Neck Lesions — 147; 23 participants

Primary: Surgical Case Completion Rate Using HVNI With or Without Converting to Alternative Mode of Oxygenation — 19; 7; 5 Participants

Primary: Apnea Hypopnea Index (AHI) — 44.89; 44.65; 36.87 events per hour — p=<0.05

Primary: Lowest Intraoperative Peripheral Oxygen Saturation (SpO2) — 97; 97 percentage of oxygen — p=0.7934

Primary: Average Oxygen Saturation by Pulse Oximetry (SpO2) (Primary Anesthesia Outcome) — 93; 98.7 percentage of saturation (SpO2) — p=0.006

Primary: Number of Participants With Presence or Absence of Blood/Secretions in Trachea and Larynx Based on Soiling Score — 12; 10; 15; 21 Participants

Primary: Delta of Apnea Hypopnea Index (AHI) as Measured by Polysomnography (PSG) — 4.27 events per hour

Primary: Proportion of Patients With Post-operative Pulmonary Complication — 2; 11 Participants

Primary: Improvement in NOSE Score — 54.8 units on a scale — p=<0.0001

Primary: Disease-free Survival at 2 Years — 111 Participants

Primary: Ability to Tolerate Measured by Percent of Participants With Protocol Goal — 50 percent of participants

Primary: Pharyngeal Critical Pressure (Pcrit) — 1.26; -1.42; -1.06 cm H2O — p=.80

Primary: Combined Total Number of Airway Interventions During an Anesthetic Sedation Case — 7; 5 Airway Interventions

Primary: Change in NOSE Score — -44.5 units on a scale

Primary: Number of the Patients With Successful Nasotracheal Intubation — 35; 18 participants

Primary: Distribution of Electrode Configurations Resulting in Greatest Retropalatal Expansion Among Cohort Subjects — 7; 3; 3; 2 Participants

Primary: Improvements in Attention/Executive Domain Index of the Developmental Neuropsychological Assessment (NEPSY) From Baseline to 7 Months. — 7.1; 5.1 units on a scale — p=0.16

Primary: Effective Apnea Hypopnea Index — 29.5; 20.0 Events per hour

Primary: Mean Apnea Hypopnea Index (AHI) at 6 Months Post-baseline — 9.86 No. of apneas/hypopneas per h of sleep

Primary: Change From Baseline NOSE Score — 53.3; 48.1; 53.5 units on a scale — p=<0.0001

Primary: Number of Participants With Cormack-Lehane Grade >2 Obtained With CMAC D Blade — 37 Participants

Primary: Median Change in Apnea-hypopnea Index (AHI) — 3.8; 8.0 events per hour of sleep — p=.590

Primary: Change in Number of Subjects Without Oxygenation Abnormalities — 12; 10 Participants — p=0.54

Primary: Change in Behavioral Index After 6 Months of CPAP or No-CPAP — -2.7; .9; -1.2 T score — p=0.07

Primary: Change in Nasal Obstructive Symptom Evaluation (NOSE) Scores From Baseline to 3 Months — -47.6 score on a scale

Primary: Sleep Apnea Severity as Measured by Apnea-hypopnea Index (AHI) — 16.4; 15.8 Events/hour

Primary: Percentage Distribution of Cook's Modification of Cormack-Lehane's Grading System. Each Study Subject Will Receive a Grade of 1, 2A, 2B, 3A, 3B, or 4 in the…

Primary: Feasibility-Number of Participants Who Complete the Three-month Protocol — 8; 10 Participants

Primary: Quality of Life (QoL) Outcomes Between Adenoidectomy + Maxillary Sinus Irrigation With or Without the Use of Balloon Dilation or Maxillary Sinus Ostia. — 2.48; 2.5…

Primary: Nasal Obstruction Symptom Evaluation (NOSE) Scale - 3 Month Responder Rate — 88.3; 42.5 percentage of participants