Phase 2 N=5 Clostridium Histolyticum Collagenase Injection for Urethral Disease
Urethral Stricture
Primary: Number of Subjects With Complication After Treatment — 0 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=101 Prostatic Urethral Lift in Subject With Acute Urinary Retention
Acute Urinary Retention · Benign Prostatic Hyperplasia
Primary: Successful Trial Without Catheter Peri-procedurally — 29; 0 Participants
N/A N=24 The RELIEF™ Ureteral Stent - Assessment of Retrograde Urinary Reflux and Distal Coil Bladder Position
Ureteral Obstruction
Primary: Incidence of Bladder Irritation Symptoms (e.g. Frequency, Urgency, Nocturia, Urine Leakage...) Associated With the RELIEF Stent. — 51.95 Units on a scale
N/A N=18 WallFlex Esophageal Fully Covered (FC) Benign Anastomotic Stricture
Refractory Anastomotic Esophageal Strictures
Primary: Number of Dilation Procedures — 5.4; 2.4 Dilation procedures — p=0.159
N/A N=95 Impact Ureteral Sheath Design During Ureteroscopy
Renal Stone · Nephrolithiasis · Urolithiasis
Primary: Number of Participants With Successful Sheath Placement — 37; 39 Participants
N/A N=24 Drainage of Malignant Extrinsic Ureteral Obstruction Using the Memokath Ureteral Stent
Ureteral Obstruction
Primary: Mean Stent Dwell Time — 17; 3.97 months
N/A N=107 Use of The Spanner Temporary Prostatic Stent as an Alternative to a Urinary Catheter to Achieve Bladder Drainage in Men
Urinary Retention
Primary: Number of Participants Who Achieved Post-void Residual (PVR) of ≤150 ml Over 90 Days — 79 Participants
Phase 3 N=187 WallFlex Biliary Fully Covered (FC) Benign Stricture Study
Biliary Stricture
Primary: Stent Removability — 132 Participants
N/A N=130 Ureteroscope Caliber and Surgeon Stress
Ureteral Stones · Ureteroscopic Lithotripsy
Primary: Change in STAI-TX1 Score (Postoperative - Preoperative) — 1.35; 5.05 Scores on a scale
Phase 2 N=25 Autologous Cell Therapy for Stress Urinary Incontinence in Males Following Prostate Surgery
Urinary Incontinence · Stress · Urination Disorders
Primary: Rate of Product-related, Biopsy Procedure-related, and Injection Procedure-related Adverse Events — 0; 2; 0; 12 events
N/A N=36 Removable GORE VIABIL® Biliary Endoprosthesis for Treatment of Benign Biliary Strictures
Biliary Strictures
Primary: Safe Stent Removal — 33 Participants
N/A N=26 Outcomes of Esophageal Self Dilation for Benign Refractory Esophageal Stricture Management
Esophageal Dilation · Refractory Benign Esophageal Stricture
Primary: Number of Endoscopic Interventions — 12; 11; 12; 7 endoscopies
N/A N=112 Covered Metallic Stents for First-Line Treatment of Benign Bile Duct Strictures
Common Bile Duct Stricture
Primary: Early Clinical Success — 50; 41 Participants
Phase 4 N=77 Therapeutic Merit of Solifenacin in the Mitigation of Ureteral Stent-induced Pain and Lower Urinary Tract Symptoms
Flank Pain · Urinary Bladder, Overactive
Primary: Change in Post-ureteroscopy Stent-induced Pain — 4.61; 3.11 units on a scale
N/A N=219 Better Lithotripsy and Ureteroscopy Evaluation of Stenting (BLUES)
Renal Stone · Ureteral Stone
Primary: Change in Patient-Reported Outcomes Measurement Information System (PROMIS®) Scores of Pain-intensity at 7 to 10 Days — 4.28; 2.92 T-score — p=0.26
Phase 3 N=655 Comparison of Surgical Procedures to Reduce Urinary Stress Incontinence
Urinary Incontinence
Primary: 24 Month Cumulative Success Rate Computed From Kaplan Meier Time-to-event Analysis (Reported as Percent Success). — 38; 47 % success at 24 months — p=0.01
N/A N=150 Return of Continence Following Robot-Assisted Radical Prostatectomy With or Without a Urethrovesical Sling
Urinary Incontinence · Prostate Cancer
Primary: Number of Continent Patients Post Prostatectomy — 37; 32 participants
Early Phase 1 N=53 ROBUST I Pilot Study, Re-Establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease
Stricture Urethra
Primary: Rate of Treatment Related Serious Complication — 0 percentage of participants
N/A N=67 Antibiotic Use Following Distal and Mid-shaft Hypospadias Repair
Hypospadias
Primary: Number of Participants With Urinary Tract Infection — 30; 22; 0; 0 Participants
N/A N=36 A Randomized Controlled Trial of the Uresta Continence Pessary
Stress Urinary Incontinence
Primary: A 50% Reduction in Pad Test Weight — 12; 4 Participants
N/A N=45 BULLET: Bladder Ultrasound Limits Length (of Time), Expedites Treatment
Point-of-Care Bladder Ultrasound · Urethral Catheter
Primary: Time to Successful Completion of Pelvic Ultrasound — 103.95; 92.82 minutes
N/A N=115 Artificial Urinary Sphincter Clinical Outcomes
Stress Urinary Incontinence
Primary: Number of Subjects With Reduction in 24 Hour Pad Weight Test at 12 Months — 91 Participants — p=< 0.001
N/A N=23 Evaluation of the Use of Metal Stents as Part of the Treatment of Benign Biliary Strictures
Benign Biliary Strictures
Primary: Short Term Success Rate in the Resolution of Biliary Strictures — 22; 14; 3; 5 participants
N/A N=90 Ureteral Stents Versus Percutaneous Nephrostomy for Initial Urinary Drainage
Children · Obstructive Uropathy · Acute Renal Failure
Primary: Period to Return to Normal Creatinine — 2.22; 2.18 days
Phase 4 N=181 Treatment of Symptoms After Stent Placement for Urinary Tract Obstruction
Ureteral Obstruction
Primary: Ureteral Stent Symptom Questionnaire Score Up to 24 Hours Prior to Stent Insertion — 1.76; 1.84; 2.02; 1.93 score on a scale
N/A N=491 Urinary Retention After Laparoscopic Inguinal Hernia Repair: Comparing the Use of the Intraoperative Urinary Catheter
Inguinal Hernia
Primary: Number of Participants With Post Operative Urinary Retention — 23; 21 Participants
Phase 3 N=37 Bladder Scan of Residual Urine With New Catheter
Urinary Incontinence
Primary: Mean Residual Urine Volume — 12.4; 9.4 mL
N/A N=23 Effect of Urethral Analgesia on Voiding
Urethral Analgesia
Primary: Voiding Efficiency — 87; 90 Percent voiding efficiency
Phase 4 N=610 Decreasing Rates of Intraurethral Catheterization Postoperatively in Spine Surgery
Post-operative Urinary Retention
Primary: Number of Patients Who Undergo Postoperative Catheterization for Urinary Retention — 23; 25 Participants — p=.96
N/A N=108 Occlusion Balloon vs. 5FR Ureteral Catheter
Kidney Stones
Primary: Number of Participants With Ureteral Stone Fragments Identified Endoscopically — 2; 8 Participants