N/A N=21 Vacuum-Assisted Dressings (V-AD) in the Management of Open Chest Wounds
Open Chest Wounds
Primary: Duration of Negative Pressure Wound Therapy (NWPT) — 8 Days
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=16 OxyGenesys Dissolved Oxygen Dressing; Abdominoplasty at Northwestern University
Wounds
Primary: Healing in Days. — 13.1; 12.5 days
N/A N=63 Vacuum Assisted Closure as a Treatment for Open Fractures
Orthopaedic Traumatic Open Fractures
Primary: Healing of Orthopaedic Trauma Open Fractures — 3.2; 4.0 use days
N/A N=111 Fluid Lavage of Open Wounds (FLOW): Pilot Trial
Infection · Wound Healing Problem · Nonunion
Primary: The Number of Participants With Re-operations (All Subsequent Operative Procedures to Treat an Infection, a Wound Healing Problem, or a Nonunion). — 7; 6; 3; 10…
Phase 2 N=5 Hidradenitis Suppurativa Wound Care
Hidradenitis Suppurativa (HS)
Primary: Percent Change in Wound Size — 57.2 percentage change in wound size
N/A N=170 Evaluating the Efficacy and Safety of the VERAFLO™ Dressing Kit for Wound Bed Preparation in Open Wounds
Wound Healing
Primary: Wound Volume Reduction Rate (Unit: %) — 62.15; 65.04 percentage of baseline wound volume
Phase 3 N=87 Efficacy and Safety of 0.25% Timolol Gel in Healing Surgical Open Wounds
Wound of Skin · Wound Heal · Wound Open
Primary: Number of Participants With Re-epithelialization at 30 Days Post op — 9; 12 participants — p=0.580
N/A N=5 Wound Dressing With Moisture Sensor
Ulcer, Leg · Heal Wound
Primary: Number of Dressing Changes With Sensor Activation at Correct Timing — 0; 0; 4; 2 Dressing changes
N/A N=46 Continuous Diffusion of Oxygen Treatment for Incision Wounds
Surgical Wound · Breast Surgery · Mammoplasty
Primary: Wound Size at 4 Weeks — 1.5; 2.75; 0.15 cm^2
Phase 4 N=14 ABRA Abdominal Closure System in Open Abdomen Management
Open Abdomen
Primary: Primary Closure Rate — 75; 67 % of participants
Phase 4 N=21 Wound Management for Sacral Pressure Ulcers With Necrotic Tissue
Pressure Ulcers
Primary: Percentage of Wounds Healed — 63.1; 6.1 percentage of wounds
N/A N=539 Treatment Study of Vacuum Assisted Closure for Postsurgical Subcutaneous Abdominal Wound Healing Impairments
Wound Healing Disorder · Impaired Wound Healing · Abdominal Wound Healing Disorder
Primary: Time to Complete Wound Closure — 36.1; 39.1 Days
Phase 4 N=39 Wound Fluid Protease Levels During Use of Novel Wound Dressing
Venous Stasis Ulcers
Primary: Matrix Metalloproteinase Level in Wound Fluid — 0.71; 0.88 mcg/ml
N/A N=18 Vacuum Assisted Therapy in Emergent Contaminated Abdominal Surgeries
Gastrointestinal Injury · Complicated Diverticulitis
Primary: Rate of Surgical Site Infection — 5 Participants
Phase 1 N=15 Study to Determine if Fibrin Affects the Ability of a Wound to Heal
Effect of Test Articles on the Healing of a Wound Artificially Induced by Liquid Nitrogen Spray
Primary: Time (in Days) to Wound Closure (Healing) Defined as Skin Re-epithelialization, Without Drainage or Dressing Requirements. — 14.4; 13.3 days to wound closure — p=.3393
N/A N=109 Wound Infection Alexis Wound Retractor
Appendicitis
Primary: Post-operative Wound Infection, After Open Appendectomy — 1; 7 Participants
N/A N=40 Measuring Wounds Found on the Outside of the Body Surface
External Wounds Measured for Length by Width Using a Ruler
Primary: Within and Between Reader Agreement for the Measurement Techniques: Scout Length by Width, Scout Trace Area, and Scout Trace Perimeter — 20.07; 16.28; 16.28; 20.07…
N/A N=33 EO2 Oxygen Delivery To Study Success Rate of Surgically Closed Wounds
Surgical Wound · Diabetes · Amputation Wound
Primary: Number of Participants With Unfavorable Wound Healing Outcomes at 4 Weeks — 8; 7 Participants
N/A N=8 An Investigation to Evaluate a New Donor Site Dressing in Surgical Burn Patients
Donor Site Complication
Primary: Percentage of Participants Who Had > 95 % Epithelialization at Day 10 — 0 percentage of participants
N/A N=56 Orthopaedic Surgical Wound Closure Comparison Study
Incision, Surgical
Primary: Stony Brook Scar Evaluation Scale — 2.8; 4.09; 3.45 score on a scale
N/A N=40 Trial of Versajet Compared With Conventional Treatment in Acute and Chronic Wounds
Surgical Wound Dehiscence
Primary: Difference in Time to Closure Between Wounds Surgically Excised With VERSAJET™ Hydrosurgery System and Those Surgically Excised Using Conventional Operating Room…
N/A N=15 Hidradenitis Suppurativa (HS) Tunneling Wounds
Hidradenitis Suppurativa
Primary: Change in Microbiome — 5.46; 3.88 colony forming units per ml (CFU/ml)
N/A N=46 A Test of Different Kinds of Bandages on Healing of Wounds
Wound Healing
Primary: Time to Healing (Days) — 13.1; NA; 13.1; NA days
Phase 4 N=1,638 Pre-operative Aqueous Antiseptic Skin Solutions in Open Fractures
Surgical Site Infection · Unplanned Fracture-Related Reoperation · Open Appendicular Fracture
Primary: Number of Participants With a Superficial Incisional Surgical Site Infection (SSI) — 13; 7 Participants
N/A N=283 Open Abdomen Study Comparing ABThera™ Open Abdomen Negative Pressure Therapy System and Barker's Vacuum Packing Technique
Open Abdomen
Primary: Number of Participants With Primary Fascial Closure — 139; 69 Participants — p=0.06
N/A N=122 Closed Incision Negative Pressure Therapy vs Standard of Care
Wound Complication
Primary: Prevalence of Wound Complications — 5; 11 Participants
N/A N=105 Prevena™ vs Dermabond in Groin Wound Infections in Vascular Surgery
Wound Infection
Primary: Comparison of Healing of Groin Wounds Between Patients Treated With Prevena vs Dermabond — 41; 54 Participants
Phase 4 N=43 Open, Prosp, Rand. Invest. Evaluating Pain With Mepitel One vs.Bridal Veil and Staples on Split Thickness Skin Grafts
Deep Partial Thickness Burn · Full Thickness Burns
Primary: VAS Score for Pain Before Dressing Removal — 11.0; 4.0 units on a scale
N/A N=39 Acellular Porcine Dermal Matrix Wound Dressing in the Management of Diabetic Foot Ulcers
Diabetic Foot Ulcers
Primary: Size of Index Wound Based on Calculations Wound Width x Length x Depth 2. Size of Index Wound Based on Calculations Wound Width x Length x Depth — 2.05; 3.33 mm^3
N/A N=160 A Study Investigating the Efficacy of Various Wound Closure Devices in Reducing Postoperative Wound Complications
Joint Disease · Arthropathy
Primary: Visual Analog Scale (VAS) for Pain — 4.53; 4.48; 4.54 score on a scale