N/A N=46 A Test of Different Kinds of Bandages on Healing of Wounds
Wound Healing
Primary: Time to Healing (Days) — 13.1; NA; 13.1; NA days
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=16 OxyGenesys Dissolved Oxygen Dressing; Abdominoplasty at Northwestern University
Wounds
Primary: Healing in Days. — 13.1; 12.5 days
N/A N=21 Vacuum-Assisted Dressings (V-AD) in the Management of Open Chest Wounds
Open Chest Wounds
Primary: Duration of Negative Pressure Wound Therapy (NWPT) — 8 Days
Phase 4 N=39 Wound Fluid Protease Levels During Use of Novel Wound Dressing
Venous Stasis Ulcers
Primary: Matrix Metalloproteinase Level in Wound Fluid — 0.71; 0.88 mcg/ml
Phase 2 N=5 Hidradenitis Suppurativa Wound Care
Hidradenitis Suppurativa (HS)
Primary: Percent Change in Wound Size — 57.2 percentage change in wound size
Phase 1 N=15 Study to Determine if Fibrin Affects the Ability of a Wound to Heal
Effect of Test Articles on the Healing of a Wound Artificially Induced by Liquid Nitrogen Spray
Primary: Time (in Days) to Wound Closure (Healing) Defined as Skin Re-epithelialization, Without Drainage or Dressing Requirements. — 14.4; 13.3 days to wound closure — p=.3393
N/A N=30 Procellera and Negative Pressure Therapy for Acute Wounds
Wound
Primary: Wound Infection — 13; 12 participants
N/A N=40 Measuring Wounds Found on the Outside of the Body Surface
External Wounds Measured for Length by Width Using a Ruler
Primary: Within and Between Reader Agreement for the Measurement Techniques: Scout Length by Width, Scout Trace Area, and Scout Trace Perimeter — 20.07; 16.28; 16.28; 20.07…
N/A N=15 Hidradenitis Suppurativa (HS) Tunneling Wounds
Hidradenitis Suppurativa
Primary: Change in Microbiome — 5.46; 3.88 colony forming units per ml (CFU/ml)
N/A N=104 Treatment of Full-Thickness Wounds: NPWT Combined With Type-I Collagen Based Advanced Skin Substitute Versus NPWT Alone
Full Thickness Skin Defects · Ulcer
Primary: Percentage Change in Wound Area — 23.73; 15.21; 34.47; 22.52 percentage change
N/A N=111 Fluid Lavage of Open Wounds (FLOW): Pilot Trial
Infection · Wound Healing Problem · Nonunion
Primary: The Number of Participants With Re-operations (All Subsequent Operative Procedures to Treat an Infection, a Wound Healing Problem, or a Nonunion). — 7; 6; 3; 10…
N/A N=5 Wound Dressing With Moisture Sensor
Ulcer, Leg · Heal Wound
Primary: Number of Dressing Changes With Sensor Activation at Correct Timing — 0; 0; 4; 2 Dressing changes
N/A N=12 Feasibility Study of a Novel Device for Chronic Wounds
Ulcer · Wounds and Injuries
Primary: Ease of Use for Patients — 8; 10; 9 participants
N/A N=249 Vacuum Assisted Closure as a Treatment for Soft Tissue Injuries
Fracture of Calcaneus, Pilon or Tibial Plateau
Primary: Healing of Orthopaedic Trauma Extremity Wound Fractures (Calcaneus, Pilon and Tibial Plateau) — 99; 127 Fractures
Phase 3 N=87 Efficacy and Safety of 0.25% Timolol Gel in Healing Surgical Open Wounds
Wound of Skin · Wound Heal · Wound Open
Primary: Number of Participants With Re-epithelialization at 30 Days Post op — 9; 12 participants — p=0.580
Phase 2 N=10 Oleogel-S10 in Wound Healing of Inherited Epidermolysis Bullosa (BEB-10)
Inherited Epidermolysis Bullosa
Primary: Intra-individual Difference in Reepithelialization of Wound (Halves) at Day 14 in 'Recent Wounds' or Day 28 in 'Chronic Wounds' — 8; 0 Wounds — p==0.008
N/A N=203 AQUACEL® Ag+ Extra™ and Cutimed™ Sorbact® Dressing in the Management of Venous Leg Ulcers Over a 12-week Period
Venous Leg Ulcer · Diabetic Foot
Primary: Effectiveness of AQUACEL® Ag+ Extra™ and Cutimed® Sorbact® on Wound Management — 80; 60 Number of Wounds
N/A N=39 Acellular Porcine Dermal Matrix Wound Dressing in the Management of Diabetic Foot Ulcers
Diabetic Foot Ulcers
Primary: Size of Index Wound Based on Calculations Wound Width x Length x Depth 2. Size of Index Wound Based on Calculations Wound Width x Length x Depth — 2.05; 3.33 mm^3
N/A N=63 Vacuum Assisted Closure as a Treatment for Open Fractures
Orthopaedic Traumatic Open Fractures
Primary: Healing of Orthopaedic Trauma Open Fractures — 3.2; 4.0 use days
N/A N=35 Evaluation of Changes to Skin Microbiome With Tape-Stripped Wounds
Healthy Volunteers
Primary: Microbial Community Richness - Baseline (Day 0) — 56.5862069; 32.13043478; 43.72413793; 34.03703704 Number of bacterial taxa — p=0.071225
Phase 4 N=10 Wound Edge Changes Following Treatment With Santyl
Diabetic Foot Ulcers · Diabetic Foot Wounds
Primary: Change From Baseline in Extent of Presence/Absence of Epithelial Tongue. — NA; NA participants
N/A N=80 Treatment of Pressure Ulcers Using Biological Skin Substitutes
Pressure Sore
Primary: Percent Change in Wound Area — -78.5; -65.1 percentage change
N/A N=43 Effect of Oasis® Wound Matrix on Stage III and IV Trunk Pressure Wounds Treated With Negative Pressure Wound Therapy
Open Wound Abdominal Wall · Wound Non Healing
Primary: Closure Rate of Non-healing Wounds — 45.79; 89.98 percentage of healing
N/A N=8 Topical Collagen Powder for Healing of Acute Full-thickness Wounds
Wound of Skin · Wound Heal
Primary: Change in Wound Diameter — 95.94; 95.94 Centimeters
N/A N=71 Evaluation of HQ® Matrix Medical Wound Dressing for Healing of Donor Site Wounds
Donor Site Wound
Primary: Time to Wound Healing — 9.86; 11.35 Days — p=0.02
Phase 4 N=21 Wound Management for Sacral Pressure Ulcers With Necrotic Tissue
Pressure Ulcers
Primary: Percentage of Wounds Healed — 63.1; 6.1 percentage of wounds
N/A N=40 Trial of Versajet Compared With Conventional Treatment in Acute and Chronic Wounds
Surgical Wound Dehiscence
Primary: Difference in Time to Closure Between Wounds Surgically Excised With VERSAJET™ Hydrosurgery System and Those Surgically Excised Using Conventional Operating Room…
Phase 4 N=28 Effect of Collagenase on Healing and Scarring
Scarring · Impaired Wound Healing
Primary: Time to Complete Wound Closure Collagenase Santyl and Vehicle — 12.9; 13.0 Days — p=<0.05
N/A N=88 Evaluation of the Effects of HP828-101 Versus Standard of Care in the Management of Partial or Full Thickness Wounds
Diabetic Foot Ulcers · Pressure Ulcers
Primary: Adequate Management of the Wound Assessed by a Left Movement (Improvement) in the Modified Bates Jensen Wound Assessment Tool. — 20.28; 21.38; 20.94; 20.59 units on a…
N/A N=49 The Clinical Efficacy of Next Science Wound Gel (NXTSC) in the Healing of Chronic Wounds
Wound Infection
Primary: The Percentage of Patients Who Had a 50% or Greater Wound Size Volume Reduction After 4 Weeks of Treatment With the Next Science Wound Gel, as Compared to Wounds Treated…