N/A N=46 A Test of Different Kinds of Bandages on Healing of Wounds
Wound Healing
Primary: Time to Healing (Days) — 13.1; NA; 13.1; NA days
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=40 Measuring Wounds Found on the Outside of the Body Surface
External Wounds Measured for Length by Width Using a Ruler
Primary: Within and Between Reader Agreement for the Measurement Techniques: Scout Length by Width, Scout Trace Area, and Scout Trace Perimeter — 20.07; 16.28; 16.28; 20.07…
N/A N=249 Vacuum Assisted Closure as a Treatment for Soft Tissue Injuries
Fracture of Calcaneus, Pilon or Tibial Plateau
Primary: Healing of Orthopaedic Trauma Extremity Wound Fractures (Calcaneus, Pilon and Tibial Plateau) — 99; 127 Fractures
Phase 4 N=35 Evaluation of Skin Affix in the Emergency Room
Wounds
Primary: Wound Closure at Discharge — 100 percent of participants
Phase 4 N=39 Wound Fluid Protease Levels During Use of Novel Wound Dressing
Venous Stasis Ulcers
Primary: Matrix Metalloproteinase Level in Wound Fluid — 0.71; 0.88 mcg/ml
N/A N=1,051 Shock, Whole Blood, and Assessment of TBI S.W.A.T. (LITES TO 2)
Hemorrhagic Shock · Traumatic Brain Injury
Primary: 4 Hour Mortality — 50; 32 Participants
N/A N=111 Fluid Lavage of Open Wounds (FLOW): Pilot Trial
Infection · Wound Healing Problem · Nonunion
Primary: The Number of Participants With Re-operations (All Subsequent Operative Procedures to Treat an Infection, a Wound Healing Problem, or a Nonunion). — 7; 6; 3; 10…
Phase 3 N=244 Assessment of Mechanisms of Improved Wound Healing
Burns
Primary: Decrease Hypermetabolism as Measured by Stable Isotope Infusion Study
N/A N=21 Vacuum-Assisted Dressings (V-AD) in the Management of Open Chest Wounds
Open Chest Wounds
Primary: Duration of Negative Pressure Wound Therapy (NWPT) — 8 Days
N/A N=30 Procellera and Negative Pressure Therapy for Acute Wounds
Wound
Primary: Wound Infection — 13; 12 participants
N/A N=16 OxyGenesys Dissolved Oxygen Dressing; Abdominoplasty at Northwestern University
Wounds
Primary: Healing in Days. — 13.1; 12.5 days
N/A N=27 Assessment Of Infrared Photobiotherapy for Improved Wound Healing
Wound Healing
Primary: FACES Pain Rating Scale Scores — 2.0; 3.3 units on a scale
N/A N=5 Biological Response of Trauma Patients to Standard Trauma Resuscitation Therapy
Hemorrhagic Shock
Primary: Biological Response as Characterized by Selected Cytokines, Specifically Tumor Necrosis Factor Alpha (TNFα), Interleukin One (IL-1β), and Interleukin Six (IL-6).
N/A N=41 Damage Control for Duodenal and Combined Duodenal-Pancreatic Injuries
Injury of Duodenum · Pancreatic Injury
Primary: Duodenal-related Complications — 13; 11; 8; 19 percentage of subjects
N/A N=63 Vacuum Assisted Closure as a Treatment for Open Fractures
Orthopaedic Traumatic Open Fractures
Primary: Healing of Orthopaedic Trauma Open Fractures — 3.2; 4.0 use days
Phase 4 N=20 Acute Application of Antibiotic Powder in Open Fracture Wounds
Fractures, Open · Wounds and Injuries--Infections · Anti-Bacterial Agents
Primary: Incidence of Surgical Site Infection During the Post-operative Follow-up Period — 0; 0; 0 participants
N/A N=30 Post-Market Clinical Evaluation of the Spiracur SNaP Wound Care System for Treatment of Acute Trauma and Acute Surgical Excision Wounds
Trauma-related Wound · Surgical Wound, Recent
Primary: Wound Closure — 22 Participants
N/A N=12 Feasibility Study of a Novel Device for Chronic Wounds
Ulcer · Wounds and Injuries
Primary: Ease of Use for Patients — 8; 10; 9 participants
Phase 2 N=5 Hidradenitis Suppurativa Wound Care
Hidradenitis Suppurativa (HS)
Primary: Percent Change in Wound Size — 57.2 percentage change in wound size
Phase 3 N=12 Pain Medicine for Wound Care Procedures
Wound Care · Pain Intensity · Hyperalgesia
Primary: Pain Intensity — 3.1; 6.8 score on a scale
N/A N=121 Trauma Survivors Outcomes and Support Study IV
Posttraumatic Stress Disorder · Depression · Suicide
Primary: Change in Post Traumatic Stress Disorder (PTSD) Symptoms Over the Course of the Six Months After Injury — 47.0; 47.0; 43.9; 43.6 units on a scale — p=0.05
N/A N=80 Treatment of Pressure Ulcers Using Biological Skin Substitutes
Pressure Sore
Primary: Percent Change in Wound Area — -78.5; -65.1 percentage change
N/A N=8 An Investigation to Evaluate a New Donor Site Dressing in Surgical Burn Patients
Donor Site Complication
Primary: Percentage of Participants Who Had > 95 % Epithelialization at Day 10 — 0 percentage of participants
Phase 1 N=15 Study to Determine if Fibrin Affects the Ability of a Wound to Heal
Effect of Test Articles on the Healing of a Wound Artificially Induced by Liquid Nitrogen Spray
Primary: Time (in Days) to Wound Closure (Healing) Defined as Skin Re-epithelialization, Without Drainage or Dressing Requirements. — 14.4; 13.3 days to wound closure — p=.3393
Phase 4 N=21 Wound Management for Sacral Pressure Ulcers With Necrotic Tissue
Pressure Ulcers
Primary: Percentage of Wounds Healed — 63.1; 6.1 percentage of wounds
Phase 3 N=507 Retapamulin Versus Placebo in Secondarily-Infected Traumatic Lesions (SITL)
Skin Infections, Bacterial
Primary: Number of Participants With Clinical Success and Failure at Follow-up (7-9 Days Post Therapy) for the Primary Efficacy Population — 184; 75; 62; 38 participants — p=0.098
Phase 2 N=40 TWB-103 for Adult Patients With Split-Thickness Skin Graft Donor Site Wounds
Donor Site Complication
Primary: Number of Participants With Treatment-related AEs and SAEs (Including Infections and Bleeding) — 0; 0; 0; 0 Participants
N/A N=48 Test of the Safety, Effectiveness, & Acceptability of An Improvised Dressing for Sickle Cell Leg Ulcers in the Tropics
Sickle Cell Leg Ulcer
Primary: Number of Participants Who Experienced a Wound Complication (A Measure of Dressing Safety) — 4; 0; 0 Participants
Phase 4 N=10 Wound Edge Changes Following Treatment With Santyl
Diabetic Foot Ulcers · Diabetic Foot Wounds
Primary: Change From Baseline in Extent of Presence/Absence of Epithelial Tongue. — NA; NA participants
N/A N=35 Evaluation of Changes to Skin Microbiome With Tape-Stripped Wounds
Healthy Volunteers
Primary: Microbial Community Richness - Baseline (Day 0) — 56.5862069; 32.13043478; 43.72413793; 34.03703704 Number of bacterial taxa — p=0.071225