Clinical Trial Search

Primary: Tolerability Measured by Tolerability Questionnaire — 2.2; 2.2 score on a scale

Primary: Change in Motor Function Score as Assessed by Modified Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Part III — 0.72; 0.01 score on a…

Primary: Thermal Pain Threshold — 41.84; 42.51 Celsius

Primary: Change in Fugl-Meyer Assessment of the Upper Extremity — 5; 3.14 score on a scale

Primary: Tolerability Measured by Tolerability Questionnaire — 2; 2 score on a scale

Primary: Number of Infants Who Took All Feeds by Mouth (Responders) — 8; 11 Participants

Primary: Mean Heart Rate (Before CPT/taVNS) — 72.86; 72.0 beats per minute

Primary: Safety of Combined taVNS and TMS — 0 Participants

Primary: Resting-state Electroencephalogram (EEG) — 0.016; -0.025 Difference in alpha asymmetry (µV²).

Primary: Device Feasibility — 33.33 percent time EMG taVNS stimulation

Primary: Psychological Distress (K10) — 30.30; 29.5; 27.20; 27.10 Scores on a scale

Primary: Brain Activity Changes (Average Differences in Beta Weights From Significantly Activated Regions: Post-stimulation Minus Pre-stimulation) Evaluated Using Functional…

Primary: Blood Pressure Variability — 0.106; 0.107 coefficient of variation

Primary: CIMT Fidelity — 3.76 score on a scale

Primary: Visuomotor Skill — 1; 1; 0.870; 0.969 Ratio of the baseline value — p=0.0096

Primary: Median Absolute Change From Baseline in Electromyographic (EMG) Peak Amplitude of the Bicep/Tricep — 22.310; 7.010; 16.070; 10.055 percentage of MVC — p=0.002

Primary: Atrial Fibrillation Burden — 2; 8.5 Percent time spent in atrial fibrillatio

Primary: Rey Auditory Verbal Learning Test (Total Delayed Recall) — 6.43; 7.83 score on a scale — p=0.11

Primary: Self-reported Positive Affect — 5.89; 5.69 units on a scale

Primary: Average Daily Use of Rescue Medications for Exacerbation of Nausea/Vomiting. — 1.186; 0.551; 0.754; 0.447 medications/day

Primary: ADHD-IV Rating Scale (ADHD-RS) — 32.6 units on a scale

Primary: Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Part III — 31.00; 36.70; 25.1; 26.8 Scores on a scale

Primary: Bradycardia — 0; 0; 0; 0 Participants

Primary: Number of Participants With Serious Adverse Events — 1; 2 participants

Primary: Change in Score of Patient Health Questionnaire-9 — -8.7; -5.5 score on a scale

Primary: Echocardiographic Markers of Diastolic Dysfunction — -21.2; -23.0 percent

Primary: Level of Interleukin-6 (IL6) — 0.88; 0.84; 1.77; 2.11 pg/ml

Primary: Interleukin - 1b - Changes and Differences in the Levels — -0.222; 0.327 percent change/day — p=0.24

Primary: ADHD-IV Rating Scale (ADHD-RS) — 32.12; 32.83; 26.16; 28.53 score on a scale — p=.54

Primary: E/e' (Early Mitral Inflow Doppler Velocity to the Early Diastolic Mitral Annulus Velocity) — 10.4; 9.9 ratio