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Physical therapy and respiratory exercises reduce pain scores in patients with arteriovenous fistulasPhysical Therapy May Ease Pain From Dialysis Fistulas

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Key Takeaway
Consider physical therapy and respiratory exercises to reduce pain scores in patients with arteriovenous fistulas.

This meta-analysis evaluated the efficacy of physical therapy, including respiratory exercises and conventional measures, for managing pain in patients with arteriovenous fistulas (AVFs). The analysis included a total of 865 patients to determine the impact of these interventions on pain scores, such as VAS and NRS scores.

The meta-analysis found that physical therapy was associated with improved pain symptoms. Among the specific interventions analyzed, respiratory exercises demonstrated the best effect on reducing pain scores when compared to conventional measures. These findings suggest that incorporating specific physical therapy components may be beneficial for pain management in this population.

Limitations noted by the authors include a lack of research regarding the long-term effects of these interventions. Clinical application is currently limited by this lack of longitudinal data. However, the findings provide practical implications for developing physical therapy protocols to address pain in patients with AVFs.

How this fits prior evidence

This meta-analysis addresses a gap in managing symptomatic complications of arteriovenous fistulas. While prior coverage noted that self-management interventions for arteriovenous fistulas are diverse and still in the development stage, this study specifically identifies physical therapy and respiratory exercises as effective for pain reduction. It does not directly relate to the technical patency improvements seen with paclitaxel-coated balloon angioplasty, clip anastomosis, or systemic heparinization.

A new review looked at whether physical therapy can help people with arteriovenous fistulas, the access points used for dialysis. The review combined results from studies that included 865 patients in total. It compared physical therapy, including breathing exercises and standard care, with standard care alone.

The review found that physical therapy was linked to improved pain symptoms. Breathing exercises appeared to have the strongest effect on lowering pain scores compared with standard measures alone. The review did not report specific numbers for how much pain improved, and it did not report side effects or safety information.

This is a review of existing studies, so it shows an association, not proof that physical therapy causes pain relief. The authors also noted that more research is needed on long-term effects. The findings suggest physical therapy may be a helpful option for managing fistula-related pain, but the evidence is not yet strong enough to be definitive.

If you have an arteriovenous fistula and are dealing with pain, talk with your healthcare team about whether physical therapy might be right for you.

What this means for you:
Physical therapy, especially breathing exercises, may help ease fistula pain, but more long-term research is needed.

Common questions

What is an arteriovenous fistula?

An arteriovenous fistula (AVF) is a connection made between an artery and a vein, usually in the arm, to create a strong access point for dialysis. It is a common type of vascular access for people with kidney failure who need hemodialysis. Pain at the fistula site can be a problem for some patients.

What kind of physical therapy was studied?

The review looked at physical therapy that included respiratory exercises and conventional measures. Respiratory exercises are breathing techniques. The review compared these with conventional measures alone. It found that respiratory exercises had the best effect on reducing pain scores, though specific details of the exercises were not reported.

How much did pain improve?

The review reported that physical therapy was associated with improved pain symptoms and that respiratory exercises reduced pain scores compared with conventional measures. However, the review did not report specific numbers for how much pain improved, such as average point drops on pain scales. So the exact size of the benefit is not clear from this summary.

Are there any side effects or safety concerns?

The review did not report any information about side effects, serious adverse events, or how well patients tolerated the physical therapy. That means safety data are missing from this summary. If you are considering physical therapy, ask your healthcare provider about any risks or precautions for your situation.

Is physical therapy recommended for fistula pain?

This review suggests physical therapy may help reduce pain in patients with AVFs, but it is a review of existing studies and shows an association, not proof. The authors noted that more research is needed on long-term effects. Whether physical therapy is right for you is a decision to make with your healthcare team.

Study Details

Study typeSystematic review
Sample sizen = 865
EvidenceLevel 1
PublishedOct 2026
View Original Abstract ↓
PURPOSE: To compare the effects of different physical interventions on pain and identify the most effective intervention. DESIGN: This systematic review and network meta-analysis were conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA 2020) guidelines. METHODS: Four English- and one Chinese-language databases were searched, without restrictions on publication dates, up to April 2025. This meta-analysis included randomized controlled trials published in English or Chinese that focused on patients with arteriovenous fistulas (AVFs) and used pain scores (including VAS and NRS scores) as the primary outcome measures. A random-effects model was used for data analysis. RESULTS: Ten studies involving 865 participants were included in this meta-analysis. In the follow-up after the intervention, physical therapy was associated with improved pain symptoms. The results of the network meta-analysis showed that, in terms of pain improvement, respiratory exercises had the best effect on reducing pain scores in patients with AVFs compared with conventional measures. CONCLUSIONS: The systematic review and meta-analysis identified the effectiveness of physical therapy in reducing pain in patients with AVFs and provided practical implications for developing effective physical therapy interventions in clinical practice. CLINICAL IMPLICATIONS: Strong research is needed in the future to explore the long-term effects of physical therapy interventions. Trail Registration PROSPERO CRD: CRD420251024571.
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