In PH-LHF patients, arrhythmia types predict mortality and rehospitalization, with AT prevalence at 42.2%.

This retrospective cohort study evaluated 1,530 patients diagnosed with pulmonary hypertension and left heart failure. The primary focus was on the prevalence and predictors of specific arrhythmia types, including atrial tachycardia (AT), ventricular tachycardia (VT), and bidirectional atrial tachycardia (BA), compared against a group with no arrhythmia. The median follow-up duration was 38 months.

The study reported that 68.9% of the population had clinically significant arrhythmias. Specifically, the prevalence of AT was 42.2%, VT was 18.0%, and BA was 8.7%. A left atrial volume index (LAVI) greater than 40 ml/m² was identified as a positive predictor for AT, with an odds ratio of 2.41 and a 95% confidence interval of 1.85–3.15.

Safety data, including adverse events, serious adverse events, discontinuations, and tolerability, were not reported. The study design limits causal inference, as the authors explicitly noted that findings represent associations only. No specific practice relevance was reported, and funding or conflict of interest details were not provided.

Clinicians should interpret these prevalence rates and the association between LAVI and AT within the context of an observational design. The data do not establish causation for mortality or heart failure rehospitalization outcomes beyond the reported associations.