Lipid lowering therapy patterns in patients with ASCVD and familial hypercholesterolemia in Israel
Photo by julien Tromeur / Unsplash
Key Takeaway
Note the observed patterns of lipid lowering therapy and adherence in Israeli ASCVD and FH patients.
This retrospective database study investigated lipid lowering therapy (LLT) patterns in a population of treated patients with atherosclerotic cardiovascular disease (ASCVD), ASCVD-risk equivalent (ASCVD-RE), and familial hypercholesterolemia (FH). The study was conducted using data from Maccabi Healthcare Services in Israel.
The research focused on several secondary outcomes, including treatment patterns, adherence to lipid lowering therapy, low-density lipoprotein cholesterol (LDL-C) control, cardiovascular outcomes, and healthcare resource utilization. The study period spanned between 2013 and 2019.
Specific results regarding the primary outcome, treatment efficacy, or exact adherence rates were not reported in the provided data. No comparator group was specified for the evaluation of these therapy patterns.
Safety and tolerability data, including adverse events, serious adverse events, and discontinuation rates, were not reported. Limitations of the study were also not reported. Clinicians should note that this is an observational cohort study and results may not be generalizable to all populations.
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View Original Abstract ↓
AimsIn this retrospective study, we analyzed data from patients with hypercholesterolemia to describe treatment patterns, adherence, low-density lipoprotein cholesterol (LDL-C) control, cardiovascular outcomes, and healthcare resource utilization among treated patients in a real-world setting in Israel.MethodsDeidentified data from the medical records of patients with atherosclerotic cardiovascular disease (ASCVD), ASCVD-risk equivalent (ASCVD-RE), and familial hypercholesterolemia (FH) treated with lipid-lowering therapy (LLT) between 2013 and 2019 were analyzed. LDL-C values were based on routine laboratory reporting in Maccabi Healthcare Services and were calculated using the Friedewald equation during the study period. Controlled LDL-C was defined as LDL-C
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