Narrative review on PCSK9 inhibitors for familial hypercholesterolemia
Review explores PCSK9 inhibitors for familial hypercholesterolemia
This narrative review synthesizes evidence on PCSK9 inhibitors, including evolocumab, for familial hypercholesterolemia. The authors discuss…
This review looks at PCSK9 inhibitors like evolocumab for people with familial hypercholesterolemia. It discusses how these drugs work and t…
Lipid lowering therapy patterns in patients with ASCVD and familial hypercholesterolemia in Israel
Lipid lowering therapy patterns observed in Israeli patients
This retrospective database study examined lipid lowering therapy patterns among patients with atherosclerotic cardiovascular disease, ASCVD…
A look at how patients with high cholesterol and heart disease manage their lipid lowering therapy and treatment adherence in Israel.
Research across Hyperlipidemia
Related studies from across the Hyperlipidemia family.
Narrative review proposes framework for TWAS signature-matching in drug prioritization
New method finds better drug targets using your DNA data
This narrative review and framework proposal examines the TWAS signature-matching approach with varying parameters, including TWAS method, e…
A new gene-based method can point doctors to better drugs, but the right settings are critical for accuracy.
Bempedoic acid 180 mg/day reduces LDL-C in Japanese patients with hypercholesterolemia over 52 weeks
New Cholesterol Option Works Well for Statin Intolerant Patients
This multicenter, open-label, single-arm Phase 3 study evaluated bempedoic acid 180 mg/day in 130 Japanese patients with hypercholesterolemi…
A new cholesterol drug safely lowers bad cholesterol for one year in patients who cannot take standard statin medications.
Night shift work linked to elevated total cholesterol in male miners, cross-sectional analysis finds
Your Shift Work Raises Cholesterol Even If You Sleep Well
A cross-sectional analysis of 921 male underground miners in the Kailuan Group found night shift work (0:00–7:59) was associated with higher…
Night shift work raises cholesterol levels even when workers sleep well, proving that fixing your sleep isn't enough to protect your heart h…
NHANES data show prevalence of high total cholesterol among US adults aged 20+
How many American adults have high cholesterol? A new look at national data
An observational analysis of NHANES 2015-2018 data examined the prevalence of high total cholesterol among US adults aged ≥20 years.
A new look at national data reveals how many American adults aged 20 and older have high total cholesterol, a silent driver of heart disease…
Meta-analysis finds water-only fasting decreases HDL, increases LDL and total cholesterol
Does water-only fasting help your cholesterol? A new review suggests it might not
A systematic review and meta-analysis of 32 human studies examined water-only fasting effects on blood lipids.
Water-only fasting may lower good cholesterol and raise bad cholesterol, according to a new review of 32 human studies.
Phase 3 trial of oral PCSK9 inhibitor enlicitide in hypercholesterolemia reports no results
Can a new pill lower cholesterol as well as existing drugs?
A completed phase 3 randomized controlled trial in 301 adults with hypercholesterolemia compared oral PCSK9 inhibitor enlicitide to ezetimib…
A new cholesterol pill called enlicitide finished its final trial, but the results showing how well it lowers bad cholesterol and its safety…
Questions about familial hypercholesterolemia
What lipid lowering treatments are common for ASCVD patients with familial hypercholesterolemia in Israel?
Common lipid-lowering treatments for ASCVD patients with FH in Israel include high-intensity statins, ezetimibe, and PCSK9 inhibitors, though real-world data show many patients still have uncontrolled LDL-C.
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