Specific mutations like KRAS, BRAF, and MMR status strongly influence treatment response in colorectal cancer, guiding targeted therapy and immunotherapy decisions.
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Quality of life for colorectal cancer survivors is influenced by physical symptoms, psychological distress, social support, self-efficacy, and demographic factors like age and gender.
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Gut microbiota imbalances, including harmful bacteria like Fusobacterium nucleatum, can promote colorectal cancer through inflammation, DNA damage, and immune disruption, while beneficial microbes may offer protection.
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AI in colorectal cancer treatment faces challenges including data quality and privacy issues, lack of generalizability, interpretability problems, and regulatory validation hurdles.
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Yes, home exercise may help reduce fatigue and anxiety in colorectal cancer patients, but the evidence is low certainty and more research is needed.
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