Robotic simultaneous resection for synchronous colorectal cancer and liver metastases shows feasibility and safety in a meta-analysis.
A systematic review and meta-analysis evaluated robotic simultaneous resection in patients aged 18 or older with synchronous colorectal cancer and liver metastases. The analysis included 165 patients drawn from retrospective or prospective observational studies. The primary focus was on safety and feasibility, with secondary outcomes including operative time, blood loss, conversion rates, and complication profiles.
The cohort had a mean age of 62.8 years and a mean body mass index of 26.5. Male gender was reported in 52.0% of patients. Mean operative time was 406.5 minutes, with mean intraoperative blood loss of 150.0 mL. Conversion to open surgery occurred in 3.9% of cases. Anastomotic leaks were observed in 4.3% of patients, while Clavien-Dindo grade III or higher complications occurred in 9.3%.
R0 resection was achieved in 99.0% of cases, and 30-day mortality was 0.9%. The mean length of hospital stay was 6.7 days. Safety was supported by these low rates of serious adverse events and mortality within the 30-day follow-up period. However, the study design limits causal inference regarding the intervention itself.
Key limitations include the single-arm nature of the meta-analysis, the absence of a comparator group, and the small total sample size of 165. Selection criteria were not fully defined, and long-term oncological outcomes were not reported. Given these constraints, the evidence suggests feasibility and safety but requires further comparative studies to confirm long-term benefits.
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