Chemoimmunotherapy improves survival in solid tumors regardless of liver metastasis status
Chemoimmunotherapy helps solid tumor patients, with or without liver metastases
This systematic review and meta-analysis evaluated 25915 patients with solid tumors receiving chemoimmunotherapy versus chemotherapy alone. …
For people with solid tumors, adding immunotherapy to chemo helps survival whether or not cancer has spread to the liver.
Narrative review discusses colorectal cancer metastasis patterns with immune checkpoint inhibitors and targeted therapies
Liver metastasis linked to resistance in colorectal cancer treated with immune checkpoint inhibitors
This narrative review examines response patterns to immune checkpoint inhibitors, anti-angiogenic agents, and targeted therapies in colorect…
A review of colorectal cancer treatments suggests liver metastasis is linked to resistance against immune checkpoint inhibitors, while lung …
Meta-analysis finds R1 vascular margin acceptable for HCC but not CLM in minimally invasive liver surgery
Tumor margin choice matters differently for liver cancer types
This meta-analysis of 839 patients undergoing minimally invasive liver surgery found that R1 vascular margin (R1v) hepatectomy yields local …
For liver cancer, leaving a narrow margin is safe. For colorectal metastases, it raises recurrence risk.
SBRT with ≥70 Gy BED10 for colorectal liver metastases shows 74.5% 1-year FFLP
Can a higher radiation dose improve tumor control in liver metastases?
This retrospective cohort study of 116 patients with colorectal liver metastases treated with stereotactic body radiation therapy (SBRT) fou…
For liver cancer spread from colorectal cancer, higher radiation doses to tumors significantly lower the risk of regrowth, while multiple tu…
Serplulimab with FOLFOX showed disease control in AFP-producing gastric adenocarcinoma with liver metastases
Rare Stomach Cancer Shrinks After New Combo Treatment
This case report and literature review describes a 67-year-old man with AFP-producing gastric adenocarcinoma and liver metastases treated wi…
A rare stomach cancer that spread to the liver shrank dramatically when doctors combined standard chemotherapy with a newer immune-boosting …
Minimally invasive surgical thermal ablation shows improved technical success and safety in liver malignancy patients
Minimally invasive surgery offers safe, effective treatment for liver cancer tumors
This systematic review and meta-analysis evaluated 3983 patients with hepatocellular carcinoma or colorectal liver metastases treated with m…
Minimally invasive surgery safely destroys liver cancer tumors with just 1% failure rate and 0.25% death risk for patients who can't have fu…
Robotic simultaneous resection for synchronous colorectal cancer and liver metastases shows feasibility and safety in a meta-analysis
Robots Are Removing Colon Cancer and Liver Tumors in One Operation
This single-arm meta-analysis included 165 patients aged 18 or older with synchronous colorectal cancer and liver metastases.
Robotic surgery safely removes colon cancer and liver tumors in one operation, sparing some patients a second major procedure.
Phase II RCT finds no OS benefit for hepatectomy in colorectal cancer with liver and lung metastases
Does removing liver tumors help when lung tumors remain? A small trial offers mixed answers
A phase II randomized trial in 27 patients with colorectal adenocarcinoma and resectable liver/unresectable lung metastases compared hepatec…
A small trial stopped early found no survival benefit for liver surgery when lung tumors remain, yet patients who actually got the operation…
Questions about Liver Metastases
How do immune checkpoint inhibitors work for patients with liver metastases?
Immune checkpoint inhibitors (ICIs) show reduced effectiveness in patients with liver metastases, but combining them with local treatments or certain targeted therapies may improve outcomes.
Full answer →Can thermal ablation be used to treat colorectal liver metastases safely?
Yes, thermal ablation is a safe and effective treatment for small colorectal liver metastases, with low complication rates and survival outcomes comparable to surgery.
Full answer →Is robotic surgery safe for treating colorectal cancer and liver metastases together?
Yes, robotic surgery appears safe for treating colorectal cancer and liver metastases together in selected patients, with low conversion rates and no reported deaths in early studies.
Full answer →Does chemoimmunotherapy improve survival for patients with liver metastases?
Yes, chemoimmunotherapy improves survival in patients with liver metastases, with benefits similar to those without liver metastases, according to a large meta-analysis.
Full answer →