Willingness for new TB vaccine is 77% overall, higher in adolescents than adults in southern Mozambique.

A mixed methods study combining cross-sectional surveys and concurrent in-depth interviews assessed willingness to receive a new tuberculosis vaccine among adults, adolescents, and their caregivers in southern Mozambique. The study included 151 surveys and 23 interviews, though the publication type and specific study phase were not reported. No comparator group was defined, and the study design did not establish causality.

Overall, 77% of participants expressed willingness to receive the new TB vaccine. When analyzing results by age group, adolescents demonstrated a higher willingness to be vaccinated compared to adults. The adjusted odds ratio for adolescents versus adults was 5.6, with a 95% confidence interval of 1.7 to 17.7. Absolute numbers for the age-stratified analysis were not reported. No p-values were provided for the overall willingness estimate.

Safety and tolerability data were not reported, as adverse events, serious adverse events, discontinuations, and general tolerability were not assessed in this survey-based evaluation. The study findings are specific to southern Mozambique, limiting generalizability to other regions. No funding sources or conflicts of interest were reported.

These results may help shape vaccine introduction efforts after a TB vaccine is licensed and approved for use in this age group. Clinicians should recognize that these data reflect local attitudes in a specific context and do not predict efficacy or safety profiles of the vaccine itself.