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Patient Mode — summaries use plain language, avoiding clinical jargon.
Pediatrics
RCT
Dexmedetomidine nasal spray vs chloral hydrate for pediatric sedation: protocol only, no results yet
New plan to test nasal spray for calming children during exams
This is a protocol for a single-center randomized controlled trial of 248 children aged 2 to 6 years with ASA physical status I/II requiring…
A new study plan aims to see if a nasal spray can safely calm children during outpatient medical exams instead of using oral syrup.
Frontiers
Sep 25, 2026
Drug Pipeline
RCT
Intranasal Dexmedetomidine Plus Midazolam Improves Sedation Success Versus Chloral Hydrate in Children
Dexmedetomidine Plus Midazolam Works Better for Kids
This randomized controlled trial enrolled 180 children aged 1–6 years undergoing outpatient procedural sedation.
A common sedation combo for children fails more often and causes more side effects than a better alternative most clinics already use.
Frontiers
Apr 25, 2026