Undetectable baseline ctDNA significantly improves progression-free and overall survival in advanced NSCLC patients
Tumor DNA Levels Help Predict Outcomes in Lung Cancer Treatment
This meta-analysis of 2,107 patients evaluates the role of circulating tumor DNA (ctDNA) as a biomarker for outcomes in advanced NSCLC treat…
Testing for circulating tumor DNA may help doctors predict how well patients with advanced lung cancer respond to immunotherapy treatments.
Artificial intelligence as a mechanistic microscope and digital twin in colorectal cancer faces generalizability and regulatory validation limitations
Artificial intelligence acts as a digital microscope for colorectal cancer patients
This narrative review discusses the use of artificial intelligence as a mechanistic microscope and digital twin for patients with colorectal…
A review explores how artificial intelligence could help doctors see colorectal cancer better, though more testing is needed before patients…
Narrative review discusses Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis risks from various medications
A review explains which drugs may cause severe skin reactions like Stevens-Johnson Syndrome
This narrative review examines Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis associated with antibiotics, antiepileptics, allopuri…
This review looks at medications linked to rare but dangerous skin conditions. It helps doctors and patients understand the risks.
Immune checkpoint inhibitors before lung cancer surgery show acceptable safety profile
Immunotherapy before lung cancer surgery is safe, study finds
This meta-analysis of patients with resectable non-small cell lung cancer found that neoadjuvant or perioperative immune checkpoint inhibito…
A new analysis of 2,691 patients shows that immunotherapy before lung cancer surgery is feasible, but comes with specific surgical challenge…
Immune checkpoint inhibitors appear safe in cancer patients with pre-existing sarcoidosis
Most cancer patients with sarcoidosis stay safe on immune checkpoint inhibitor therapy
A meta-analysis examined immune checkpoint inhibitor use in cancer patients with documented pre-existing sarcoidosis. Most patients showed n…
A look at 43 patients shows most do not have a flare when taking immune checkpoint inhibitors, though some do experience a flare.
Meta-analysis shows immune checkpoint inhibitor combinations improve survival and response rates in advanced cervical cancer patients with manageable safety profiles
ICI Combinations Improve Survival for Advanced Cervical Cancer
This systematic review analyzed 4,441 patients with advanced cervical cancer to evaluate immune checkpoint inhibitor combinations. Results i…
Combining immune checkpoint inhibitors with other treatments significantly improved survival and disease control for patients with advanced …
Review: Targeting mRNA Processing Enhances Immune Checkpoint Blockade in Cancer
New cancer treatments target RNA to boost immune system power
This review examines strategies targeting mRNA processing (alternative splicing, RNA modifications, RNA editing) combined with immune checkp…
Scientists found that combining RNA processing strategies with immune checkpoint blockade creates powerful synergistic effects for treating …
Network meta-analysis suggests immune checkpoint inhibitor regimens improve survival in advanced gastric cancer compared to chemotherapy alone
New analysis suggests dual-target immune checkpoint inhibitors may improve survival for advanced gastric cancer patients
This network meta-analysis evaluated immune checkpoint inhibitor regimens versus chemotherapy for patients with advanced gastric cancer. The…
A large network meta-analysis suggests dual-target immune checkpoint inhibitors combined with chemotherapy may improve survival for advanced…
Meta-analysis links emotional distress to worse outcomes in advanced lung cancer
Emotional distress linked to worse lung cancer survival
This systematic review and meta-analysis of 911 patients with advanced NSCLC found emotional distress was significantly associated with redu…
For people with advanced lung cancer, feeling emotionally distressed is tied to lower survival and worse treatment response, a new analysis …
Narrative review discusses colorectal cancer metastasis patterns with immune checkpoint inhibitors and targeted therapies
Liver metastasis linked to resistance in colorectal cancer treated with immune checkpoint inhibitors
This narrative review examines response patterns to immune checkpoint inhibitors, anti-angiogenic agents, and targeted therapies in colorect…
A review of colorectal cancer treatments suggests liver metastasis is linked to resistance against immune checkpoint inhibitors, while lung …
Network meta-analysis compares therapies for liver metastatic uveal melanoma
Liver-directed therapy combined with ICIs leads for metastatic uveal melanoma survival
This systematic review and network meta-analysis synthesized evidence on therapeutic modalities for patients with liver metastatic uveal mel…
A network meta-analysis of 2,585 patients found liver-directed therapy combined with immune checkpoint inhibitors offered the best survival …
Review of antiviral and immunotherapeutic strategies for chronic hepatitis B
New antiviral strategies show promise for chronic hepatitis B infection
This narrative review synthesizes evidence on antiviral and immunotherapeutic strategies for chronic hepatitis B. The authors highlight func…
A review of new treatments suggests combination therapies may offer future value for managing chronic hepatitis B, cirrhosis, and liver canc…
All immune checkpoint inhibitors Articles
- Undetectable baseline ctDNA significantly improves progression-free and overall survival in advanced NSCLC patients
- Artificial intelligence as a mechanistic microscope and digital twin in colorectal cancer faces generalizability and regulatory validation limitations
- Narrative review discusses Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis risks from various medications
- Immune checkpoint inhibitors before lung cancer surgery show acceptable safety profile
- Immune checkpoint inhibitors appear safe in cancer patients with pre-existing sarcoidosis
- Meta-analysis shows immune checkpoint inhibitor combinations improve survival and response rates in advanced cervical cancer patients with manageable safety profiles
- Review: Targeting mRNA Processing Enhances Immune Checkpoint Blockade in Cancer
- Network meta-analysis suggests immune checkpoint inhibitor regimens improve survival in advanced gastric cancer compared to chemotherapy alone
- Meta-analysis links emotional distress to worse outcomes in advanced lung cancer
- Narrative review discusses colorectal cancer metastasis patterns with immune checkpoint inhibitors and targeted therapies
- Network meta-analysis compares therapies for liver metastatic uveal melanoma
- Review of antiviral and immunotherapeutic strategies for chronic hepatitis B
- Morning immune checkpoint inhibitor infusions associated with improved survival in metastatic non-small-cell lung cancer
- Meta-analysis reveals CMR and biomarkers key in ICI myocarditis
- Review outlines immunotherapy roadmap for gastric cancer patients with noted limitations
- Meta-analysis finds Type 2 diabetes linked to poorer survival in solid tumor patients on immune checkpoint inhibitors
- Narrative review on immune microenvironment evolution in serrated neoplasia and colorectal cancer
- Neoadjuvant ICI plus chemotherapy improves event-free survival in early-stage TNBC
- Early time-of-day immune checkpoint inhibitor administration improves overall survival in advanced solid tumors
- Systematic review and meta-analysis shows immune checkpoint inhibitors improve survival in first-line ES-SCLC but not as single agents in second-line
- High tumour mutation burden improves overall survival in solid tumours treated with immune checkpoint inhibitors
- CT-based immune radiomic signature shows association with prognosis in non-small cell lung cancer
- Systematic review of advancements and challenges in NK cell immunotherapy for malignancies
- Review examines thoracic radiotherapy combined with chemoimmunotherapy for extensive-stage small cell lung cancer patients
- Narrative review on ICIs in patients with viral infections and solid tumors
- Narrative review suggests time-related biases may attenuate apparent vaccine survival benefits in cancer patients
- CIPHER model predicts immune checkpoint inhibitor pneumonitis risk in non-small cell lung cancer patients
- Review of multi-omics technologies supporting immune checkpoint inhibitor use in cancer patients
- Triple therapy with TACE, TKIs, and ICIs shows survival benefits in unresectable hepatocellular carcinoma
- Review of combination strategies for digestive system tumors including gastric and colorectal cancer
- Meta-analysis of real-world studies associates COVID-19 vaccination with improved survival in cancer patients on ICIs
- Mini-review discusses combination regimens built on immune checkpoint inhibitors and their associated immune-related adverse events
- Comprehensive review compares ICI-based regimens and ICI-TKI combinations against sunitinib in metastatic renal cell carcinoma
- Narrative review discusses immune checkpoint inhibitors in lung cancer patients
- Narrative review examines driver mutations and immunotherapy response in non-small cell lung cancer
- Narrative review conceptualizes CVD as systemic immune–metabolic–inflammatory disease
- Combined neutrophil-to-lymphocyte ratio predicts progression-free survival in metastatic cervical cancer patients treated with immune checkpoint inhibitors
- Systematic review examines immune checkpoint inhibitors, innate immunity, and immune-related adverse events in cancer patients
- Immune checkpoint inhibitor regimens improve survival versus tyrosine kinase inhibitor monotherapies in advanced hepatocellular carcinoma
- In lung cancer patients, immune-checkpoint inhibitors were associated with a 16.4% incidence of thyroid irAEs
- Immune Checkpoint Inhibitors Improve Survival and Response Rates in Patients with Hepatocellular Carcinoma Compared to Standard Therapy
- Meta-analysis finds immunotherapy efficacy in HCC varies by aetiology, strongest in HBV-related disease
- Risk models for ICI-associated myocarditis occurrence and severity in patients receiving immune checkpoint inhibitors
- Adjuvant immune checkpoint inhibitors after curative HCC treatment associated with reduced recurrence risk
- Precision oncology enables targeted therapies for gynecologic cancers, though acquired resistance remains a barrier