Chemoimmunotherapy improves objective response rate and survival in advanced pulmonary large-cell neuroendocrine carcinoma
Combining Chemotherapy and Immune Therapy Improves Outcomes for Advanced Lung Cancer
This meta-analysis of 3537 patients with advanced pulmonary large-cell neuroendocrine carcinoma (LCNEC) found that chemoimmunotherapy signif…
Adding an immune-boosting drug to standard chemotherapy helps patients with a specific type of advanced lung cancer live longer.
Immune checkpoint inhibitors plus chemotherapy improve overall survival in advanced triple-negative breast cancer
Immunotherapy plus chemo improves survival in triple-negative breast cancer
This umbrella meta-analysis of 39,147 patients found that combining immune checkpoint inhibitors with chemotherapy significantly improves ov…
Adding immunotherapy to chemo helps some patients with advanced triple-negative breast cancer live longer, but side effects are more common.
Multidisciplinary determination of resectability incorporates tumor biology and perioperative systemic therapy in stage III NSCLC
New Guidelines Redefine Surgery Options for Lung Cancer Patients
This clinical guideline addresses the management of stage III non-small cell lung cancer (NSCLC). It advocates for a multidisciplinary appro…
New guidelines suggest that surgery for certain lung cancers should be based on tumor biology and treatment response rather than just anatom…
First-line immune checkpoint inhibitor therapy improves progression-free survival and overall survival in MSI-H/dMMR mCRC
Immune checkpoint inhibitors improve survival for certain colorectal cancers
This meta-analysis of more than 600 patients with metastatic colorectal cancer (mCRC) involving microsatellite instability-high or mismatch …
New analysis shows immune checkpoint inhibitors offer better survival and fewer side effects than chemotherapy for specific types of metasta…
Surgical treatment and multimodal therapies characterize management options for rare penile melanoma cases
Treatment Options and Clinical Features for Penile Melanoma
This case series and narrative review describes the clinical features and treatment landscape for patients with penile melanoma. The authors…
New research highlights surgical options and targeted therapies for penile melanoma, a rare form of skin cancer that primarily affects middl…
Immune ecotypes may offer more refined patient stratification for ccRCC than current biomarkers
Immune Ecotypes May Guide Kidney Cancer Treatment
This mini review explores the use of immune ecotypes to identify treatment-responsive profiles in patients with advanced clear cell renal ce…
New review proposes four immune subtypes in kidney cancer that could explain why some patients respond to immunotherapy and others don't.
Gut microbiome taxa and metabolites enhance immune checkpoint inhibitor efficacy and mitigate systemic toxicity
Gut bacteria may improve cancer treatment and reduce side effects
This systematic review examines the role of gut microbiota, including specific taxa like Bacteroides and Akkermansia muciniphila, in modulat…
Specific gut bacteria and their byproducts could help cancer treatments work better while protecting the heart and colon from inflammation.
Immune checkpoint inhibitors are associated with acute kidney injury and multi-organ immune-related adverse events
Immune checkpoint inhibitors linked to kidney and heart risks
This narrative review synthesizes evidence from 68 studies involving 15,392 participants regarding the safety of immune checkpoint inhibitor…
New data shows that certain cancer treatments can cause serious side effects like kidney damage and heart inflammation.
Primary and acquired resistance to immune checkpoint inhibitors in NSCLC involves antigen presentation and TME remodeling
Understanding why some lung cancer treatments do not work for every patient
This systematic review synthesizes mechanisms of primary and acquired resistance to PD-1/PD-L1 inhibitors in patients with non-small cell lu…
Doctors are studying why certain immune-boosting drugs fail to stop lung cancer growth. New insights help find better ways to treat patients…
LncRNA signatures predict ICI response and survival across cancers in systematic review
lncRNA Signatures May Help Predict Response to Cancer Treatment
A systematic review of 31 studies found that lncRNA-based signatures consistently stratify cancer patients into groups with significantly di…
Specific genetic markers called lncRNAs may help doctors predict how well cancer patients will respond to immune checkpoint inhibitor treatm…
Neoadjuvant chemoimmunotherapy improves pathological response and surgical rates in resectable esophageal squamous cell carcinoma
Immune therapy shows promise for esophageal squamous cell carcinoma
This meta-analysis of randomized controlled trials involving 1070 patients found that neoadjuvant chemoimmunotherapy (NIC) significantly imp…
Adding immune checkpoint inhibitors to chemotherapy before surgery significantly improves tumor response rates in patients with esophageal c…
Synergistic Effects of Immune Checkpoint Inhibitors and Radiotherapy in Solid Tumor Management
Combining immune checkpoint inhibitors and radiotherapy improves survival outcomes
Meta-analysis data indicates that combining immune checkpoint inhibitors with radiotherapy significantly improves survival outcomes in solid…
New data shows that adding immune checkpoint inhibitors to radiation therapy can improve survival for patients with many types of solid tumo…
All immune checkpoint inhibitors Articles
- Chemoimmunotherapy improves objective response rate and survival in advanced pulmonary large-cell neuroendocrine carcinoma
- Multidisciplinary determination of resectability incorporates tumor biology and perioperative systemic therapy in stage III NSCLC
- Immune checkpoint inhibitors plus chemotherapy improve overall survival in advanced triple-negative breast cancer
- First-line immune checkpoint inhibitor therapy improves progression-free survival and overall survival in MSI-H/dMMR mCRC
- Surgical treatment and multimodal therapies characterize management options for rare penile melanoma cases
- Immune ecotypes may offer more refined patient stratification for ccRCC than current biomarkers
- Gut microbiome taxa and metabolites enhance immune checkpoint inhibitor efficacy and mitigate systemic toxicity
- Primary and acquired resistance to immune checkpoint inhibitors in NSCLC involves antigen presentation and TME remodeling
- LncRNA signatures predict ICI response and survival across cancers in systematic review
- Immune checkpoint inhibitors are associated with acute kidney injury and multi-organ immune-related adverse events
- Neoadjuvant chemoimmunotherapy improves pathological response and surgical rates in resectable esophageal squamous cell carcinoma
- Synergistic Effects of Immune Checkpoint Inhibitors and Radiotherapy in Solid Tumor Management
- Single-cell and spatial omics provide detailed mapping of tumor-immune ecosystems in non-small cell lung cancer
- Intrathecal chemotherapy provides objective response rates of 34.5% to 86.4% in non-small-cell lung cancer leptomeningeal metastasis
- Nanomedicine delivery systems may enhance immunotherapy efficacy in colorectal cancer
- Elevated troponin levels are associated with increased risk of MACE and all-cause mortality in ICI-associated myocarditis
- Combination of Local Treatment and Systemic Therapy Improves Outcomes in Patients with Hepatocellular Carcinoma
- Pseudoprogression in immune checkpoint inhibitor therapy is associated with modest tumor growth and early progression
- Undetectable baseline ctDNA significantly improves progression-free and overall survival in advanced NSCLC patients
- Bibliometric analysis maps research trends and key contributors in immune checkpoint inhibitors for endometrial cancer
- Artificial intelligence as a mechanistic microscope and digital twin in colorectal cancer faces generalizability and regulatory validation limitations
- Narrative review discusses Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis risks from various medications
- Immune checkpoint inhibitors before lung cancer surgery show acceptable safety profile
- Immune checkpoint inhibitors appear safe in cancer patients with pre-existing sarcoidosis
- Meta-analysis shows immune checkpoint inhibitor combinations improve survival and response rates in advanced cervical cancer patients with manageable safety profiles
- Review: Targeting mRNA Processing Enhances Immune Checkpoint Blockade in Cancer
- Network meta-analysis suggests immune checkpoint inhibitor regimens improve survival in advanced gastric cancer compared to chemotherapy alone
- Meta-analysis links emotional distress to worse outcomes in advanced lung cancer
- Narrative review discusses colorectal cancer metastasis patterns with immune checkpoint inhibitors and targeted therapies
- Network meta-analysis compares therapies for liver metastatic uveal melanoma
- Systematic review of immune checkpoint inhibitors in cancer efficacy and safety
- Review of antiviral and immunotherapeutic strategies for chronic hepatitis B
- Morning immune checkpoint inhibitor infusions associated with improved survival in metastatic non-small-cell lung cancer
- Meta-analysis reveals CMR and biomarkers key in ICI myocarditis
- Review outlines immunotherapy roadmap for gastric cancer patients with noted limitations
- Meta-analysis finds Type 2 diabetes linked to poorer survival in solid tumor patients on immune checkpoint inhibitors
- Narrative review on immune microenvironment evolution in serrated neoplasia and colorectal cancer
- Narrative Review Explores Immune Checkpoint Inhibition in Pediatric Medulloblastoma
- Review of immune checkpoint inhibitor-associated diabetes mellitus in two patients
- Neoadjuvant ICI plus chemotherapy improves event-free survival in early-stage TNBC
- Early time-of-day immune checkpoint inhibitor administration improves overall survival in advanced solid tumors
- Systematic review and meta-analysis shows immune checkpoint inhibitors improve survival in first-line ES-SCLC but not as single agents in second-line
- High tumour mutation burden improves overall survival in solid tumours treated with immune checkpoint inhibitors
- CT-based immune radiomic signature shows association with prognosis in non-small cell lung cancer
- Systematic review of advancements and challenges in NK cell immunotherapy for malignancies
- Review examines thoracic radiotherapy combined with chemoimmunotherapy for extensive-stage small cell lung cancer patients
- Narrative review on ICIs in patients with viral infections and solid tumors
- Narrative review suggests time-related biases may attenuate apparent vaccine survival benefits in cancer patients
- CIPHER model predicts immune checkpoint inhibitor pneumonitis risk in non-small cell lung cancer patients
- Review of immunotherapy innovations for triple-negative breast cancer survival
- Review of multi-omics technologies supporting immune checkpoint inhibitor use in cancer patients
- Triple therapy with TACE, TKIs, and ICIs shows survival benefits in unresectable hepatocellular carcinoma
- Review of combination strategies for digestive system tumors including gastric and colorectal cancer
- Meta-analysis of real-world studies associates COVID-19 vaccination with improved survival in cancer patients on ICIs
- Mini-review discusses combination regimens built on immune checkpoint inhibitors and their associated immune-related adverse events
- Comprehensive review compares ICI-based regimens and ICI-TKI combinations against sunitinib in metastatic renal cell carcinoma
- Narrative review discusses immune checkpoint inhibitors in lung cancer patients
- Narrative review examines driver mutations and immunotherapy response in non-small cell lung cancer
- Narrative review conceptualizes CVD as systemic immune–metabolic–inflammatory disease
- Combined neutrophil-to-lymphocyte ratio predicts progression-free survival in metastatic cervical cancer patients treated with immune checkpoint inhibitors
- Systematic review examines immune checkpoint inhibitors, innate immunity, and immune-related adverse events in cancer patients
- Immune checkpoint inhibitor regimens improve survival versus tyrosine kinase inhibitor monotherapies in advanced hepatocellular carcinoma
- In lung cancer patients, immune-checkpoint inhibitors were associated with a 16.4% incidence of thyroid irAEs
- Immune Checkpoint Inhibitors Improve Survival and Response Rates in Patients with Hepatocellular Carcinoma Compared to Standard Therapy
- Meta-analysis finds immunotherapy efficacy in HCC varies by aetiology, strongest in HBV-related disease
- Risk models for ICI-associated myocarditis occurrence and severity in patients receiving immune checkpoint inhibitors
- Adjuvant immune checkpoint inhibitors after curative HCC treatment associated with reduced recurrence risk
- Precision oncology enables targeted therapies for gynecologic cancers, though acquired resistance remains a barrier