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Home › Medications › corticosteroids

corticosteroids

34 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of corticosteroids

34 trials tracked of corticosteroids: 26 in phase 3 or 4 and 5 with published results. The most-cited published study has 244 citations.

34Trials tracked
26Phase 3 & 4
0Recruiting
5With published results
Phase distribution
Phase 4 11 Phase 3 15 Phase 2 7 Other / NA 1
  1. Phase 4 Advancing Renal TRANSplant eFficacy and Safety Outcomes With an eveRolimus-based regiMen (TRANSFORM) Completed · 244 cited
  2. Phase 3 An Efficacy and Safety Study of Tocilizumab (RoActemra/Actemra) in Participants With Giant Cell Arteritis (GCA) Completed · 131 cited
  3. Phase 4 Efficacy of Everolimus in Combination With Tacrolimus in Liver Transplant Recipients Completed · 30 cited
  4. Phase 3 12 Month Athena Study: Everolimus vs. Standard Regimen in de Novo Kidney Transplant Patients Completed · 13 cited
  5. Phase 3 Caplacizumab and Immunosuppressive Therapy Without Firstline Therapeutic Plasma Exchange in Adults With Immune-mediated Thrombotic Thrombocytopenic Purpura Completed · 1 cited
  6. Phase 4 A Study Investigating the Renal Tolerability, Efficacy, and Safety of a CNI-free Versus a Standard Regimen in de Novo Heart Transplant (HTx) Recipients Completed
Show 28 more trials
  1. Phase 4 SCHEDULE Follow Up Visit 5-7 yr Completed
  2. Phase 4 Kidney Spare the Nephron (STN) Study - A Study of CellCept (Mycophenolate Mofetil) and Rapamune (Sirolimus) in Kidney Transplant Recipients Completed
  3. Phase 4 A Study of CellCept (Mycophenolate Mofetil) Combined With Tacrolimus and Corticosteroids in Kidney Transplant Patients. Completed
  4. Phase 4 A Twelve-month, Multicenter, Open-label, Randomized Study of the Safety, Tolerability and Efficacy of Everolimus With Basiliximab, Corticosteroids and Two Different Exposure Levels of Tacrolimus in de Novo Renal Transplant Recipients Completed
  5. Phase 4 Evaluation of Early Conversion to Everolimus From Cyclosporine in de Novo Renal Transplant Recipients Completed
  6. Phase 4 SCHEDULE - Scandinavian Heart Transplant Everolimus de Novo Study With Early Calcineurin Inhibitor (CNI) Avoidance Completed
  7. Phase 4 Efficacy and Safety of Everolimus With Enteric-Coated Mycophenolate Sodium (EC-MPS) in a Cyclosporine Microemulsion-free Regimen Compared to Standard Therapy in de Novo Renal Transplant Patients Completed
  8. Phase 4 Efficacy and Safety of Everolimus+EC-MPS After Early CNI Elimination vs EC-MPS +Tacrolimus in Renal Transplant Recipients Completed
  9. Phase 3 A National Multi-center Randomized, Open Label Study to Evaluate Efficacy and Safety of Everolimus With EC-MPS Compared to Standard Treatment Combination Tacrolimus and EC-MPS in de Novo Liver Transplant Recipients Completed
  10. Phase 3 Tacrolimus/Everolimus Versus Tacrolimus/Enteric-Coated Mycophenolate Sodium Completed
  11. Phase 3 A Study of Omalizumab (Xolair) in Subjects With Moderate to Severe Persistent Asthma (EXTRA) Completed
  12. Phase 3 Enteric-coated Mycophenolate Sodium (EC-MPS) With Reduced-dose Tacrolimus Versus EC-MPS With Standard-dose Tacrolimus in Stable Kidney Transplant Recipients Completed
  13. Phase 3 Efficacy and Safety Study of Everolimus Plus Reduced Cyclosporine Versus Mycophenolic Acid Plus Cyclosporine in Kidney Transplant Recipients Completed
  14. Phase 3 Efficacy and Safety of Concentration-controlled Everolimus to Eliminate or to Reduce Tacrolimus Compared to Tacrolimus in de Novo Liver Transplant Recipients Completed
  15. Phase 3 Efficacy and Safety of Everolimus in Recipients of Heart Transplants to Prevent Acute and Chronic Rejection Completed
  16. Phase 3 A Study of RoActemra/Actemra (Tocilizumab) in Patients With Active Systemic Juvenile Idiopathic Arthritis (JIA) Completed
  17. Phase 3 Progression of Renal Interstitial Fibrosis / Tubular Atrophy (IF/TA) According to Epithelial-mesenchymal Transition (EMT) and Immunosuppressive Regimen (Everolimus Based Versus CNI Based) in de Novo Renal Transplant Recipients Completed
  18. Phase 3 Extension Study to Evaluate the Long-term Efficacy and Safety of Everolimus in Liver Transplant Recipients Completed
  19. Phase 3 A Study of CellCept (Mycophenolate Mofetil) in Combination Therapy in Heart Transplant Patients. Completed
  20. Phase 3 Study Evaluating Sirolimus in Kidney Transplant Recipients Completed
  21. Phase 2 Pharmacodynamics, Efficacy and Safety of Basiliximab 40 or 80 mg in Combination With Ciclosporine Microemulsion or Everolimus, in Adult Low Risk de Novo Renal Transplant Recipients (IDEALE Study) Completed
  22. Phase 2 Study Comparing the Safety and Efficacy of Belatacept With That of Cyclosporine in Patients With a Transplanted Kidney Completed
  23. Phase 2 Combined Kidney and Bone Marrow Transplantation to Prevent Kidney Transplant Rejection Completed
  24. Phase 2 Regimen Optimization Study Completed
  25. Phase 2 Gradual Withdrawal of Immune System Suppressing Drugs in Patients Receiving a Liver Transplant Completed
  26. Phase 2 A Study Comparing Obinutuzumab (RO5072759; GA101) 1000 Milligram (mg) Versus 2000 mg in Participants With Previously Untreated Chronic Lymphocytic Leukemia (CLL) (GAGE) Completed
  27. Phase 2 A Study to Assess the Safety and Efficacy of Alefacept in Kidney Transplant Recipients Completed
  28. N/A A Randomized, Double-Blinded, Placebo-Controlled Trial of Corticosteroid Therapy Following Portoenterostomy Completed

Showing the 34 most-cited and recently-updated of 34 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Nemolizumab Q4W improves IGA success maintenance by 11.8% over withdrawal in atopic dermatitis
Dermatology RCT
Nemolizumab Q4W improves IGA success maintenance by 11.8% over withdrawal in atopic dermatitis Trial shows nemolizumab maintains skin results for atopic dermatitis
This Phase 3 randomized controlled trial evaluated nemolizumab in 507 adolescents and adults with moderate-to-severe atopic dermatitis who w…
A new trial found that nemolizumab helps maintain clear skin and reduce itching for adults and teens with moderate to severe atopic dermatit…
Jun 13, 2026
Adjunctive corticosteroids may modestly reduce hospital stay for bacterial facial infections but evidence certainty is low
Infectious Disease Meta-analysis
Adjunctive corticosteroids may modestly reduce hospital stay for bacterial facial infections but evidence certainty is low Adding steroids to facial infection treatment may shorten hospital stays by about one and a half days
This systematic review and meta-analysis evaluated adjunctive corticosteroid therapy versus standard treatment alone in patients with bacter…
A large review found that adding steroids to standard care for facial infections might shorten hospital stays, but the evidence is not yet s…
Jun 1, 2026
Immunomodulatory therapies showed no mortality benefit or neurological harm in 2605 adults after cardiac arrest
Emergency Medicine Meta-analysis
Immunomodulatory therapies showed no mortality benefit or neurological harm in 2605 adults after cardiac arrest New drug review shows no benefit for heart attack survivors
This systematic review and meta-analysis evaluated immunomodulatory therapeutics in adults following in- and out-of-hospital cardiac arrest.…
A large review of immune drugs found no clear benefit for heart attack survivors and did not lower death rates within 30 days.
Jun 1, 2026
Systemic corticosteroid therapy significantly decreased length of hospital stay and fever duration in children with community-acquired pneumonia
Infectious Disease Meta-analysis
Systemic corticosteroid therapy significantly decreased length of hospital stay and fever duration in children with community-acquired pneumonia Shorter hospital stays and fever for kids with pneumonia using steroids
This systematic review and meta-analysis evaluated systemic corticosteroid therapy versus controls in children with community-acquired pneum…
A large review found that adding steroids to standard antibiotics helped children with pneumonia leave the hospital faster and get over thei…
Jun 1, 2026
Kounis syndrome shows male predominance 75 percent and 4 percent mortality in systematic review
Allergy & Immunology Meta-analysis
Kounis syndrome shows male predominance 75 percent and 4 percent mortality in systematic review Most patients with Kounis syndrome recover well, though some face serious risks
This systematic review and meta-analysis of 71 cases of Kounis syndrome synthesized demographic patterns, clinical features, and outcomes. T…
A review of 71 cases shows most people with Kounis syndrome recover, but some face heart attacks or death.
Jun 1, 2026
Case report details treatment of ANCA-associated vasculitis with Evans syndrome and cerebral infarction in a 72-year-old woman
Cardiology Sys. Review
Case report details treatment of ANCA-associated vasculitis with Evans syndrome and cerebral infarction in a 72-year-old woman Treatment stabilized some symptoms but not others in a single patient case
This case report describes a 72-year-old female with ANCA-associated vasculitis, Evans syndrome, and cerebral infarction treated with cortic…
A 72-year-old woman with complex blood vessel disease saw some health markers improve while others remained poor after specific treatments.
Frontiers May 26, 2026
Fecal Microbial Transplantation Shows Promise for Treating Gastrointestinal Acute Graft-Versus-Host Disease in Patients
Infectious Disease Meta-analysis
Fecal Microbial Transplantation Shows Promise for Treating Gastrointestinal Acute Graft-Versus-Host Disease in Patients Fecal transplant shows promise for gut graft-versus-host disease
A meta-analysis of 262 patients found that fecal microbial transplantation significantly improved complete response rates for gastrointestin…
A review of 262 patients found fecal transplants may improve gut graft-versus-host disease response rates compared to standard drugs.
Frontiers May 22, 2026
Marburg MS case shows treatment challenges and fatal outcome
Dermatology Sys. Review
Marburg MS case shows treatment challenges and fatal outcome A Rare MS Variant Defied Treatment Until This Switch
A 46-year-old woman with aggressive Marburg MS faced treatment-limiting toxicity and died despite multiple therapies, highlighting urgent ca…
A woman with a rare, aggressive form of multiple sclerosis tried many treatments without success, and doctors tried a new approach too late.
Frontiers May 15, 2026
Narrative review suggests suprachoroidal injections may improve vision and reduce edema in diabetic macular edema
Rheumatology Sys. Review
Narrative review suggests suprachoroidal injections may improve vision and reduce edema in diabetic macular edema New eye injection method reduces shots and protects vision for diabetics
This narrative review examines suprachoroidal space injections versus conventional intravitreal therapies for diabetic macular edema. The au…
A new injection technique for diabetic eye disease could spare patients from frequent shots and lower the risk of cataracts while improving …
Frontiers May 12, 2026
Systematic review and meta-analysis of herpes zoster risk in rheumatoid arthritis patients
Rheumatology Meta-analysis
Systematic review and meta-analysis of herpes zoster risk in rheumatoid arthritis patients Rheumatoid Arthritis Patients Face Higher Shingles Risk Than General Public
This systematic review and meta-analysis synthesized data on herpes zoster risk in rheumatoid arthritis patients. The pooled proportion of h…
People with rheumatoid arthritis have a much higher chance of getting shingles, and doctors must watch for specific risk factors like high s…
Frontiers May 9, 2026
Systematic review and meta-analysis of repeat corticosteroids in PPROM shows increased maternal infection risk
Pulmonology & Critical Care Meta-analysis
Systematic review and meta-analysis of repeat corticosteroids in PPROM shows increased maternal infection risk Repeat steroid shots for PPROM may raise infection risk without helping babies
This systematic review and meta-analysis evaluated repeat courses of corticosteroids versus a single course in women with preterm premature …
A new review suggests giving two rounds of steroids to women with PPROM could hurt the mother without helping the baby
May 7, 2026
Clinical features and treatment responses in 40 male patients with VEXAS syndrome
Neurology Cohort
Clinical features and treatment responses in 40 male patients with VEXAS syndrome HMA treatment shows promise for VEXAS syndrome patients
This retrospective multicenter study of 40 male patients with VEXAS syndrome evaluated clinical features and various treatment responses.
New data on VEXAS syndrome suggests that hypomethylating agents may help improve clinical and biological responses in men.
Frontiers Apr 30, 2026

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