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Home › Medications › daptomycin

daptomycin

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of daptomycin

18 trials tracked of daptomycin: 10 in phase 3 or 4 and 4 with published results. The most-cited published study has 97 citations.

18Trials tracked
10Phase 3 & 4
0Recruiting
4With published results
Phase distribution
Phase 4 5 Phase 3 5 Phase 2 5 Phase 1 2 Other / NA 1
  1. Phase 3 Ceftobiprole in the Treatment of Patients With Staphylococcus Aureus Bacteremia Completed · 97 cited
  2. Phase 4 Safety & Efficacy of Daptomycin Versus Standard of Care (SOC) in 1 - 17 Year Olds With Staphylococcus Aureus Bacteremia (MK-3009-005) Completed · 56 cited
  3. Phase 3 Safety and Efficacy Study of Daptomycin Compared to Active Comparator in Pediatric Participants With Acute Hematogenous Osteomyelitis (AHO) (MK-3009-006) Completed · 30 cited
  4. Phase 3 Pharmacokinetics of Daptomycin During Cardiopulmonary Bypass Surgery Completed · 8 cited
  5. Phase 4 Safety and Efficacy Study of Daptomycin in Pediatric Participants (1 to 17 Years-old) With Skin and Skin Structure Infections Completed
  6. Phase 4 Daptomycin Versus Vancomycin in Participants With Skin Infections Due to MRSA Completed
Show 12 more trials
  1. Phase 4 Evaluation of Daptomycin for the Emergency Department Treatment of Complicated Skin and Skin Structure Infections Completed
  2. Phase 4 Pharmacokinetics of Daptomycin in Critically Ill Patients Receiving Continuous Venovenous Hemodialysis (CVVHD) Completed
  3. Phase 3 Study to Compare Efficacy and Safety of Daptomycin in Elderly Patients With Complicated Skin and Soft Tissue Infections Completed
  4. Phase 3 China Registration Study in Patients With Skin Infections Completed
  5. Phase 2 Daptomycin in Treating Neutropenia and Fever in Patients With Cancer Completed
  6. Phase 2 DOTS: Dalbavancin as an Option for Treatment of Staphylococcus Aureus Bacteremia Completed
  7. Phase 2 PHASE II SINGLE-CENTER, RANDOMIZED, OPEN-LABEL, PROSPECTIVE, STUDY TO DETERMINE THE IMPACT OF SERIAL PROCALCITONIN Completed
  8. Phase 2 Catheter Related - Gram Positive Bloodstream Infections Completed
  9. Phase 2 Study of Daptomycin in Subjects Undergoing Surgery for Osteomyelitis Associated With an Infected Prosthetic Caused by Staphylococci Completed
  10. Phase 1 Study to Evaluate Daptomycin Given During Dialysis and After Dialysis Completed
  11. Phase 1 An Open Label Study to Describe the Pharmacokinetics of Daptomycin in Infants Completed
  12. N/A Study of the Pharmacokinetics of Daptomycin in Children With Renal Disease Completed

Showing the 18 most-cited and recently-updated of 18 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Positive in vitro interactions with β-lactam linked to lower 14-day mortality in MRSA bacteraemia
Infectious Disease RCT
Positive in vitro interactions with β-lactam linked to lower 14-day mortality in MRSA bacteraemia Positive lab interactions linked to lower early death in MRSA infection treatment
This post hoc analysis of a multicentre randomized trial included 150 adults with MRSA bacteraemia.
When lab tests showed bacteria died better with combined drugs, patients had lower early death rates. This finding suggests smarter drug pai…
May 1, 2026
Five medications including daptomycin and durvalumab show positive association with drug-induced eosinophilic pneumonia in database analysis
Rheumatology Cohort
Five medications including daptomycin and durvalumab show positive association with drug-induced eosinophilic pneumonia in database analysis 15,000 Cases Found: Which Drugs Harm Your Lungs?
A retrospective pharmacovigilance investigation analyzed 15,374 cases in FAERS and Vigibase databases to identify drug-induced eosinophilic …
A massive data review reveals which medicines might silently damage your lungs.
Frontiers Apr 22, 2026