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Home › Medications › lisdexamfetamine

lisdexamfetamine

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of lisdexamfetamine

31 trials tracked of lisdexamfetamine: 22 in phase 3 or 4 and 5 with published results. The most-cited published study has 157 citations.

31Trials tracked
22Phase 3 & 4
0Recruiting
5With published results
Phase distribution
Phase 4 14 Phase 3 8 Phase 2 5 Phase 1 3 Other / NA 1
  1. Phase 3 Evaluate the Maintenance of Efficacy of SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder Completed · 157 cited
  2. Phase 4 LDX and Functional Magnetic Resonance Imaging (fMRI in Menopausal Women Completed · 86 cited
  3. Phase 4 Attention & Memory Impairments in Menopausal Women Completed · 86 cited
  4. Phase 4 Neurobiological Basis of Response to Vyvanse in Adults With ADHD: an fMRI Study of Brain Activation Completed · 10 cited
  5. Phase 3 Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Acute Treatment Completed · 1 cited
  6. Phase 4 Lisdexamfetamine Dimesylate in Residual Symptoms and Cognitive Impairment in Major Depressive Disorder. Completed
Show 25 more trials
  1. Phase 4 Treatment of Traumatic Brain Injury (TBI)-Related Attention Deficits in Children Completed
  2. Phase 4 IMProving Executive Function Study Completed
  3. Phase 4 Effects of LDX on Functioning of College Students With ADHD Completed
  4. Phase 4 Cardiovascular Study of Lisdexamfetamine in Healthy and Hypertensive Attention Deficit Hyperactivity Disorder Adults Completed
  5. Phase 4 Does Pharmacological Treatment of Attention Deficit Hyperactivity Disorder (ADHD) in Adults Enhance Parenting Performance? Completed
  6. Phase 4 Lisdexamfetamine Dimesylate 2-year Safety Study in Children and Adolescents With Attention-Deficit/Hyperactivity Disorder (ADHD) Completed
  7. Phase 4 Effectiveness of Vyvanse Compared to Concerta in Adolescents With Attention-deficit/Hyperactivity Disorder Completed
  8. Phase 4 Effectiveness of Vyvanse Compared to Concerta in Adolescents With Attention-deficit/Hyperactivity Disorder Completed
  9. Phase 4 Comparing the Effectiveness of New Versus Older Treatments for Attention Deficit Hyperactivity Disorder (The NOTA Study) Completed
  10. Phase 4 Efficacy and Safety of Lisdexamfetamine Dimesylate in Adults With Chronic Fatigue Syndrome Completed
  11. Phase 3 Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Maintenance Treatment Completed
  12. Phase 3 Vyvanse Adolescent Open-Label Safety and Efficacy Extension Study Completed
  13. Phase 3 Randomized, Double-blind Safety and Efficacy Study of Lisdexamfetamine Dimesylate (LDX) in Children and Adolescents Aged 6-17 Completed
  14. Phase 3 Comparison of Lisdexamfetamine Dimesylate With Atomoxetine HCl in Attention-Deficit/Hyperactivity Disorder (ADHD) Subjects With an Inadequate Response to Methylphenidate Completed
  15. Phase 3 Double-blind, Placebo-controlled, Randomised Withdrawal, Extension, Safety and Efficacy Study of LDX in Children and Adolescents Aged 6-17 Completed
  16. Phase 3 Open Label Extension in Adults With Binge Eating Disorder (BED) Completed
  17. Phase 2 Shire SCT: Lisdexamfetamine Treatment for ADHD and SCT Completed
  18. Phase 2 Forced-dose Titration of SPD489 in Adults With Binge Eating Disorder Completed
  19. Phase 2 Characterization and Sequential Pharmacotherapy of Severe Mood Dysregulation Completed
  20. Phase 2 Study of Lisdexamfetamine Sulfate to Treat Cognitive Dysfunction in Multiple Sclerosis Completed
  21. Phase 2 Open-Label Pilot Study of Lisdexamfetamine for Cocaine Dependence Completed
  22. Phase 1 Lisdexamfetamine Dimesylate (LDX) Pilot Cognition Study to Evaluate the Utility of a Standardized Battery of Tests in Adults With Attention-Deficit Hyperactivity Disorder (ADHD) Completed
  23. Phase 1 Bioavailability Study of SPD489 Administered With Two Different Means of Administration in Healthy Adult Volunteers Completed
  24. Phase 1 Vyvanse and Adderall XR Given Alone and in Combination With Prilosec OTC Completed
  25. N/A Imaging the Effects of Stimulant Medication on Emotional Lability in Patients With ADHD Completed

Showing the 31 most-cited and recently-updated of 31 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
FDA Approves Vyvanse (lisdexamfetamine) for Binge Eating Disorder in Adults
Psychiatry FDA Approval
FDA Approves Vyvanse (lisdexamfetamine) for Binge Eating Disorder in Adults FDA approves Vyvanse to treat binge eating disorder in adults
The FDA approved Vyvanse (lisdexamfetamine) for moderate to severe binge eating disorder (BED) in adults.
The FDA has approved Vyvanse (lisdexamfetamine) for moderate to severe binge eating disorder in adults.
FDA Apr 29, 2026
FDA Approves Vyvanse (lisdexamfetamine) for Binge Eating Disorder
Psychiatry FDA Approval
FDA Approves Vyvanse (lisdexamfetamine) for Binge Eating Disorder FDA approves Vyvanse to treat binge eating disorder in adults
FDA approved Vyvanse (lisdexamfetamine) for moderate to severe binge eating disorder (BED) in adults.
The FDA approved Vyvanse for moderate to severe binge eating disorder in adults. It is a stimulant already used for ADHD. This gives patient…
FDA Apr 29, 2026