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Home › Medications › MESNA

MESNA

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of MESNA

38 trials tracked of MESNA: 2 in phase 3 or 4.

38Trials tracked
2Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 4 1 Phase 3 1 Phase 2 29 Phase 1 3 Other / NA 4
  1. Phase 4 Lenalidomide and Dexamethasone With/Without Stem Cell Transplant in Patients With Multiple Myeloma Completed
  2. Phase 3 Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Ependymoma Completed
  3. Phase 2 Off-the-shelf NK Cells + SCT for Myeloid Malignancies Completed
  4. Phase 2 Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia Completed
  5. Phase 2 Chemotherapy and Stem Cell Transplantation in Treating Patients With Stage IIIB Breast Cancer Completed
  6. Phase 2 Chemotherapy Plus Ofatumumab Followed by G-CSF for Mobilization of Peripheral Blood Stem Cells in Patients With Non-Hodgkin's Lymphomas Completed
Show 32 more trials
  1. Phase 2 Efficacy of the HCVIDDOXIL Regimen in Patients With Newly Diagnosed Peripheral T-Cell Lymphoma Completed
  2. Phase 2 Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors Completed
  3. Phase 2 R-MACLO-IVAM and Thalidomide in Untreated Mantle Cell Lymphoma Completed
  4. Phase 2 RAD001 Study in Treatment of Relapsed or Refractory Acute Lymphocytic Leukemia Completed
  5. Phase 2 Lymphocyte Depletion and Stem Cell Transplantation to Treat Severe Systemic Lupus Erythematosus Completed
  6. Phase 2 Study of Bortezomib in Combination With Cyclophosphamide and Rituximab Completed
  7. Phase 2 Panobinostat Plus Ifosfamide, Carboplatin, and Etoposide (ICE) Compared With ICE For Relapsed Hodgkin Lymphoma Completed
  8. Phase 2 Hyper-CVAD With Liposomal Vincristine in Acute Lymphoblastic Leukemia Completed
  9. Phase 2 Protracted Etoposide During Induction Therapy for High Risk Neuroblastoma Completed
  10. Phase 2 Study of Hyper-CVAD Plus Imatinib Mesylate for Philadelphia-Positive Acute Lymphocytic Leukemia Completed
  11. Phase 2 Vinblastine, Celecoxib, and Combination Chemotherapy in Treating Patients With Newly-Diagnosed Metastatic Ewing's Sarcoma Family of Tumors Completed
  12. Phase 2 Therapy for Children With Advanced Stage Neuroblastoma Completed
  13. Phase 2 Thiotepa-Clofarabine-Busulfan With Allogeneic Stem Cell Transplant for High Risk Malignancies Completed
  14. Phase 2 High-dose Chemotherapy for Poor-Prognosis Relapsed Germ-Cell Tumors Completed
  15. Phase 2 Haploidentical Donor Hematopoietic Progenitor Cell and NK Cell Transplantation for Hematologic Malignancy Completed
  16. Phase 2 Modified Hyper-CVAD (Cyclophosphamide, Vincristine, Adriamycin, and Dexamethasone) Program for Acute Lymphoblastic Leukemia Completed
  17. Phase 2 Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma Completed
  18. Phase 2 Research Study to Determine if an Experimental Agent, LLME Can Decrease the Incidence and Severity of Graft-Versus-Host-Disease (GVHD) Following Blood (Hematopoietic) Stem Cell Transplantation Completed
  19. Phase 2 Hematopoietic Stem Cell Transplant in Devic's Disease Completed
  20. Phase 2 Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMTCTN1507) Completed
  21. Phase 2 Trial of Mesna to Prevent Doxorubicin-induced Plasma Protein Oxidation and Tumor Necrosis Factor Alpha (TNF-α) Release Completed
  22. Phase 2 Randomized Double Cord Blood Transplant Study Completed
  23. Phase 2 Rituximab and Combination Chemotherapy in Treating Patients With Previously Untreated Mantle Cell Lymphoma Completed
  24. Phase 2 Mismatched Transplantation Using High-dose Post-transplant Cyclophosphamide Completed
  25. Phase 2 Umbilical & Cord Blood (CB) Derived CAR-Engineered NK Cells for B Lymphoid Malignancies Completed
  26. Phase 1 Busulfan, Melphalan, and Stem Cell Transplant After Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Completed
  27. Phase 1 A Study of Olaratumab (LY3012207), Doxorubicin, and Ifosfamide in Participants With Advanced or Metastatic Soft Tissue Sarcoma Completed
  28. Phase 1 Zoledronic Acid and Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma Completed
  29. N/A Haploidentical (Half-matched) Related Donor Stem Cell Transplantation Using Killer Immunoglobulin-like Receptors in Addition to Normal Selection Factors to Determine the Best Donor Completed
  30. N/A Palonosetron in Sarcoma Patients Receiving Chemotherapy With Adriamycin and Ifosfamide (AI) Completed
  31. N/A Fosaprepitant in Patients Receiving Ifosfamide-based Regimen Completed
  32. N/A TCR-α/β and CD19 Depleted Stem Cell Grafts From Haplo Donors for HSCT in Relapsed Lymphoma Completed

Showing the 38 most-cited and recently-updated of 38 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
PPSS shows rapid metastatic progression despite neoadjuvant Adriamycin, Ifosfamide, and Mesna
Oncology Guideline
PPSS shows rapid metastatic progression despite neoadjuvant Adriamycin, Ifosfamide, and Mesna Case Report Details Aggressive Synovial Sarcoma After Treatment
This case report describes a 60-year-old woman with primary pulmonary synovial sarcoma who received neoadjuvant Adriamycin, Ifosfamide, and …
A 60-year-old woman's synovial sarcoma shrank with chemo, but spread widely just four months after surgery.
Frontiers Sep 13, 2026
MESNA-assisted surgery disrupts disease-associated microbiota equilibrium in paediatric cholesteatomatous chronic otitis media
Infectious Disease Guideline
MESNA-assisted surgery disrupts disease-associated microbiota equilibrium in paediatric cholesteatomatous chronic otitis media Early data suggest MESNA may help restore ear bacteria in children with chronic ear infections
This observational review characterizes the microbiota of paediatric patients with cholesteatomatous chronic otitis media (CCOM) and evaluat…
A small review links MESNA-assisted surgery to changes in ear bacteria, offering hope for preventing infection return in children.
Frontiers May 28, 2026