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Home › Medications › pirtobrutinib

pirtobrutinib

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials of pirtobrutinib

11 trials tracked of pirtobrutinib.

11Trials tracked
0Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 1 11
  1. Phase 1 A Drug Drug Interaction (DDI) Study of Pirtobrutinib (LOXO-305) and Different Formulations of Midazolam in Healthy Participants Completed
  2. Phase 1 A Study to Evaluate Pirtobrutinib (LOXO-305) in Healthy Adult Participants Completed
  3. Phase 1 A Study of Effect of Multiple Doses of LOXO-305 on the Pharmacokinetics of Single Oral Doses of CYP1A2, CYP2C9, CYP2C19 Substrates in Healthy Participants Completed
  4. Phase 1 Study of Pirtobrutinib (LOXO-305) in Participants With Impaired Kidney Function and Healthy Participants Completed
  5. Phase 1 A Study of the Effects of Pirtobrutinib (LOXO-305) on Repaglinide (CYP2C8 Substrate) in Healthy Participants Completed
  6. Phase 1 Study of Pirtobrutinib (LOXO-305) in Participants With Impaired Liver Function and Healthy Participants Completed
Show 5 more trials
  1. Phase 1 A Drug Drug Interaction (DDI) Study of Pirtobrutinib (LOXO-305) and Digoxin (P-Glycoprotein Substrate) in Healthy Participants Completed
  2. Phase 1 A Study of Two Different Formulations of Pirtobrutinib (LOXO-305) In Healthy Participants Completed
  3. Phase 1 A Study to Evaluate the Effect of Pirtobrutinib (LOXO-305) on QTc Interval in Healthy Participants Completed
  4. Phase 1 A Study of the Effect of Food on Pirtobrutinib (LOXO-305) in Healthy Participants Completed
  5. Phase 1 A Drug Drug Interaction (DDI) Study of Pirtobrutinib (LY3527727) and Rosuvastatin in Healthy Participants Completed

Showing the 11 most-cited and recently-updated of 11 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Pirtobrutinib shows activity in relapsed and refractory marginal zone lymphoma patients in a Phase 1/2 trial
Oncology Phase I
Pirtobrutinib shows activity in relapsed and refractory marginal zone lymphoma patients in a Phase 1/2 trial Early trial shows pirtobrutinib helped some patients with relapsed marginal zone lymphoma
This Phase 1/2 trial evaluated pirtobrutinib in 36 patients with relapsed and refractory marginal zone lymphoma.
A new drug helped more than half of patients with relapsed lymphoma shrink their tumors, offering hope for those who have run out of other t…
Apr 16, 2026