This review looked at how natural products, such as plant polyphenols, traditional Chinese medicine formulas, and natural polysaccharides, might affect people with chronic kidney disease (CKD). The research focused on the link between the gut and the kidneys. In many cases, an imbalance in gut bacteria can lead to a buildup of harmful toxins and cause inflammation or scarring in the kidneys.
The findings suggest that these natural products could help by reshaping gut bacteria and repairing the intestinal barrier. By balancing metabolic profiles, these substances may offer a way to protect kidney function and slow down disease progression for those with various conditions, including lupus nephritis and IgA nephropathy.
It is important to note that this review focuses on theoretical foundations and potential strategies rather than proven clinical results for specific products. Because the evidence is based on theoretical models of how these substances work, they are not currently established treatments. Patients should talk to their doctor before starting any new supplements or herbal formulas.
