When a person suffers a major stroke, every second counts. Doctors often use a procedure called mechanical thrombectomy to physically remove a clot from a large blood vessel. This trial looks at what happens next. It aims to see if giving a medicine called alteplase directly into the artery can improve the final outcome for these patients.
The study will involve 440 adults who have a large vessel occlusion, which is a serious blockage of a main artery in the brain. These patients will have already undergone a successful procedure to open the vessel. The researchers want to know if a 15-minute infusion of alteplase helps them achieve a better quality of life and better physical function after 90 days.
It is important to note that this is currently a study protocol. This means the researchers have designed the plan and are preparing to start, but they have not finished the study yet. Because the trial is in the planning stages, there are no results or safety data available at this time.