Observational study finds pregnant women with SARS-CoV-2 infection more likely to need ICU care and ventilation

An observational study compared outcomes between pregnant and nonpregnant women of reproductive age with laboratory-confirmed SARS-CoV-2 infection in the United States. The study did not report sample size, follow-up duration, or primary outcome. The analysis found that pregnant women with SARS-CoV-2 infection were more likely to be admitted to an intensive care unit and to receive mechanical ventilation compared to nonpregnant women. The study did not report effect sizes, absolute numbers, p-values, or confidence intervals for these outcomes. Safety and tolerability data, including adverse events and discontinuations, were not reported. Key limitations include the observational design, which can only show association, not causation. The lack of reported effect measures, absolute risks, and confidence intervals prevents assessment of the magnitude or precision of the observed associations. Funding sources and potential conflicts of interest were also not reported. The practice relevance of these findings is not reported. Given the observational nature and incomplete reporting of key metrics, these results should be interpreted as preliminary signals requiring confirmation in more robust studies before informing clinical practice.