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Robotic gastrectomy shows no significant difference compared to laparoscopic gastrectomy for East Asian patientsRobotic Surgery Shows No Difference from Laparoscopic Gastrectomy

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Key Takeaway
Note that robotic gastrectomy shows no significant difference from laparoscopic gastrectomy in this East Asian cohort.

This meta-analysis evaluates the comparative outcomes of robotic gastrectomy versus laparoscopic gastrectomy in East Asian patients with overweight, obesity, or high visceral adiposity undergoing surgery for gastric cancer. The analysis synthesized data from 1,695 patients regarding overall complications and 1,858 patients regarding major complications.

For the primary outcomes, the study found no significant difference in overall postoperative complications (RR 0.81; 95% CI 0.60 to 1.10; P=0.153) or major postoperative complications (RR 0.56; 95% CI 0.20 to 1.52; P=0.210). Additionally, no significant differences were observed in operative time (mean difference +31.13 min; 95% CI -9.60 to +71.86; P=0.111) or estimated blood loss (mean difference -10.27 mL; 95% CI -38.20 to +17.66; P=0.388).

The authors note that the evidence for all primary outcomes is of very-low-certainty. Furthermore, the applicability of these findings to Western patients is uncertain due to the specific study population. Clinical application of these results should be interpreted with caution given the low certainty of the evidence.

How this fits prior evidence

This meta-analysis addresses a gap in comparing surgical modalities for gastric cancer. While previous evidence noted that thymosin alpha1 plus chemotherapy may improve short-term response and safety in gastric cancer, and electrical acupoint stimulation may speed gut recovery after surgery, this study focuses on the surgical technique itself. It provides data on robotic versus laparoscopic gastrectomy in a specific East Asian cohort, though the evidence quality is very-low-certainty.

Researchers looked at the differences between robotic and laparoscopic surgery for patients with gastric cancer. The study focused on East Asian patients who were overweight or had high body fat and were undergoing a gastrectomy. This specific group was chosen to see if robotic tools provided any unique advantages in complex cases.

The analysis compared several key factors, including the time spent in surgery, the amount of blood lost, and the number of complications after the operation. The results showed no significant differences between the two methods. Specifically, there was no significant difference in overall complications, major complications, operative time, or blood loss.

It is important to note that the evidence for these findings is of very low certainty. Additionally, because the study focused on East Asian patients, the results may not apply to patients in Western countries. Patients should discuss these surgical options with their doctors to determine the best approach for their specific needs.

What this means for you:
Robotic and laparoscopic surgeries for gastric cancer showed similar results in terms of safety and operation time.

Common questions

Is robotic surgery safer than laparoscopic surgery for gastric cancer?

The study found no significant difference in overall postoperative complications or major complications between robotic and laparoscopic surgery. Both methods showed similar safety outcomes for the patients included in the study, which primarily consisted of East Asian patients with high body fat.

Does robotic surgery take longer than laparoscopic surgery?

The data showed no significant difference in operative time between the two methods. While the average time for robotic surgery was about 31 minutes longer, the statistical analysis did not confirm a significant difference between the two surgical techniques.

Is robotic surgery better for patients with high body fat?

The study specifically looked at East Asian patients with overweight or high visceral adiposity. In this group, robotic surgery did not show a significant advantage over laparoscopic surgery regarding blood loss or complication rates.

Study Details

Study typeMeta analysis
Sample sizen = 1,695
EvidenceLevel 1
PublishedSep 2026
View Original Abstract ↓
High body mass index (BMI) and CT-defined visceral adiposity may increase the technical difficulty of minimally invasive gastrectomy for gastric cancer. Whether robotic gastrectomy offers a comparative advantage over laparoscopic gastrectomy in these adiposity-defined populations is uncertain. PubMed/MEDLINE, Scopus, and the Cochrane Library were searched from inception to 29 August 2026 using prespecified strategies; reference lists were also checked. English-language comparative studies of robotic versus laparoscopic gastrectomy for gastric malignancy were eligible when overweight, obesity, or high visceral adiposity was defined categorically and arm-level data were extractable. Two reviewers independently performed screening, extraction, ROBINS-I assessment, and conventional GRADE assessment. Overlapping cohorts were resolved outcome by outcome. Random-effects models used restricted maximum likelihood with modified Hartung-Knapp confidence intervals. Primary outcomes were overall postoperative complications, major postoperative complications, operative time, and estimated blood loss. In total, 16 studies were eligible, all from South Korea, China, or Japan. Overall complications did not differ significantly between robotic and laparoscopic gastrectomy (10 studies; 1,695 participants; RR 0.81, 95% CI 0.60 to 1.10; P = 0.153; I²=0%). Major complications yielded an RR of 0.56 (8 studies; 1,858 participants; 95% CI 0.20 to 1.52; P = 0.210; I²=53%). The pooled mean difference in operative time was + 31.13 min (7 studies; 1,037 participants; 95% CI - 9.60 to + 71.86; P = 0.111; I²=92%), while the mean difference in estimated blood loss was - 10.27 mL (6 studies; 939 participants; 95% CI - 38.20 to + 17.66; P = 0.388; I²=74%). The certainty of evidence was very low for all primary outcomes. In East Asian patients with overweight, obesity, or high visceral adiposity undergoing gastrectomy for gastric cancer, very-low-certainty evidence did not establish a clear difference between robotic and laparoscopic surgery for any primary outcome. Applicability to Western patients remains uncertain. Future prospective multicenter studies, including Western populations and using standardized adiposity definitions and patient-centered outcomes, are needed to clarify the comparative value of robotic and laparoscopic gastrectomy.
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