Researchers looked at the relationship between a specific protein called sFlt-1 and peripartum cardiomyopathy (PPCM). PPCM is a rare condition where the heart muscle weakens during the time around childbirth. The study included 226 women who were either pregnant or had recently given birth.
The findings show that higher levels of this protein are linked to an increased risk of heart problems. This link was even stronger in women who also had pre-eclampsia, a pregnancy complication involving high blood pressure. While the protein showed some ability to identify the condition, its overall diagnostic performance was only modest.
It is important to note that these results come from a small number of studies and show an association rather than a direct cause. Because the measurements were taken after birth, this test cannot currently be used to screen for heart issues during pregnancy. These findings are still early and exploratory due to how rare the condition is.