Mode
Text Size
Log in / Sign up

Multisensory interventions improve neurodevelopmental outcomes in preterm infants compared to standard or unisensory careMultisensory Interventions Improve Neurodevelopmental Outcomes for Preterm Infants

AI-generated summary of the cited source, checked by automated accuracy review. How we work

Key Takeaway
Consider multisensory interventions in the NICU to improve neurodevelopmental outcomes in preterm infants.

This meta-analysis synthesized data from 13 studies to evaluate the impact of multisensory interventions—defined as stimuli targeting two or more sensory modalities—on neurodevelopmental outcomes in preterm infants. The analysis compared these interventions against standard neonatal care or standard care supplemented with only a single sensory intervention.

The primary finding indicates that multisensory interventions resulted in significantly better neurodevelopmental outcomes than the comparator groups, with an effect size of SMD = 0.96 (95% CI: 0.47 to 1.45). While most studies were conducted within the NICU setting, two included studies involved intervention continuation after discharge.

Limitations regarding evidence certainty and specific follow-up durations were not reported in the data. The findings may inform clinical practice for NICU protocols aimed at improving neurodevelopmental trajectories in preterm infants. However, clinicians should note that while the effect size is statistically significant, the lack of reported certainty metrics necessitates a cautious interpretation of the magnitude of benefit.

How this fits prior evidence

This meta-analysis addresses gaps in neonatal care by focusing on sensory interventions. It complements prior evidence regarding NICU environments where noise levels from alarms and respiratory devices frequently exceed limits. While previous findings established that preterm birth is linked to higher pain intensity, this study specifically evaluates the efficacy of multisensory stimuli to improve neurodevelopmental outcomes.

A review of 13 studies looked at how different types of sensory input affect preterm infants in the neonatal intensive care unit. Researchers compared a multisensory approach, which targets two or more senses at once, against standard care or treatments that only target one sense.

The results showed that babies receiving multisensory interventions had significantly better neurodevelopmental outcomes than those who received standard care or single-sensory treatments. The data indicated a notable improvement in these developmental markers for the infants involved in the study.

While most of the care took place in the hospital, some studies included follow-up care after the babies were discharged. Because this was a review of several different trials, it provides a broader look at how multisensory methods might help early development. You should talk with your medical team to see if these types of interventions are appropriate for a specific infant's needs.

What this means for you:
Multisensory care may improve neurodevelopmental outcomes for preterm infants compared to single-sensory care.

Common questions

What is a multisensory intervention?

A multisensory intervention involves providing stimuli that target two or more senses at the same time. In this study, these interventions were compared to standard care or treatments that only targeted one sense. The goal is to provide a more comprehensive sensory experience for preterm infants in the NICU.

How does multisensory care help preterm babies?

The analysis of 13 studies found that infants receiving multisensory interventions had significantly better neurodevelopmental outcomes than those receiving standard care. The results showed a positive effect size, suggesting these methods may support better development for infants born prematurely.

Where did these interventions take place?

Most of the interventions occurred within the neonatal intensive care unit (NICU). However, it is important to note that two of the studies included follow-up care that continued after the infants were discharged from the hospital.

Study Details

Study typeMeta analysis
EvidenceLevel 1
PublishedAug 2026
View Original Abstract ↓
BackgroundThis systematic review and meta-analysis aimed to evaluate the impact of multisensory interventions primarily initiated during NICU hospitalization or before discharge on neurodevelopment in preterm infants, informing clinical practice. While most interventions were delivered during the NICU stay, a minority involved post-discharge continuation through parental care plans. The study was conducted in strict accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and was registered with PROSPERO (CRD420251090728).MethodsRandomized controlled trials (RCTs) comparing the effects of multisensory intervention vs. standard neonatal care on neurological outcomes were included. The majority of interventions were delivered during NICU hospitalization; two studies involved post-discharge continuation through parental-implemented care plans. The intervention group received stimuli targeting two or more sensory modalities, while the control group received standard care or standard care supplemented with a single sensory intervention.ResultsA total of 13 studies meeting the eligibility criteria were included in the meta-analysis. The pooled statistical analysis revealed that preterm infants receiving multisensory intervention exhibited significantly better neurodevelopmental outcomes compared to those receiving standard care or unisensory intervention (SMD = 0.96, 95% CI: 0.47 1.45, P 
Free Newsletter

Clinical research that matters. Delivered to your inbox.

Join thousands of clinicians and researchers. No spam, unsubscribe anytime.