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Systematic review and meta-analysis identifies factors associated with hearing recovery in pediatric sudden hearing loss

Systematic review and meta-analysis identifies factors associated with hearing recovery in pediatric…
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Key Takeaway
Note male gender and treatment delay of 14 days or less associated with better recovery children sudden hearing loss.

This systematic review and meta-analysis focuses on pediatric patients with sudden sensorineural hearing loss. The authors synthesized available data to identify clinical factors associated with hearing recovery outcomes. The source document does not report the specific sample size or the setting where the studies were conducted. Intervention and comparator details were also not reported. Primary outcomes focused on hearing recovery.

Male gender was associated with better hearing recovery with an odds ratio of 1.911 and a P value of 0.034. Treatment delay of 14 days or less was also associated with better hearing recovery. This association had an odds ratio of 6.402 and a P value of 0.034. No absolute numbers were reported for these outcomes. Follow-up duration was not reported.

Safety data including adverse events were not reported in the synthesis. The authors note the evidence provides a reference for developing prevention strategies and optimizing therapeutic interventions. Clinicians should interpret these associations cautiously without assuming causality. The certainty of the evidence was not reported by the authors. Funding or conflicts of interest were not reported.

Secondary outcomes were not reported in the provided data. The practice relevance centers on using these findings to guide clinical decision making for pediatric cases. Further research is needed to confirm these associations in different populations.

Study Details

Study typeMeta analysis
EvidenceLevel 1
PublishedApr 2026
View Original Abstract ↓
ObjectiveThis systematic review and meta-analysis aimed to identify prognostic factors influencing hearing recovery in children with sudden sensorineural hearing loss (SSNHL), thereby providing a reference for developing prevention strategies and optimizing therapeutic interventions.MethodsWe conducted a comprehensive search of PubMed, Web of Science, Cochrane Library, Embase, CNKI, and SinoMed databases to identify relevant studies published prior to 2024. Inclusion criteria encompassed pediatric patients with SSNHL (12 years (OR: 1.911, P = 0.034), treatment delay ≤ 14 days (OR: 6.402, P 
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