Hospital-acquired infections associated with higher costs and length of stay in discharged cancer center patients.

This retrospective cohort study evaluated discharged patients at a regional cancer center with conditions including cancer-related nosocomial infections and malignant neoplasm of thoracic esophagus. The sample size was not reported. Patients were categorized by exposure to hospital-acquired infections compared against non-HAI patients. Follow-up duration was not reported.

The infected group demonstrated significantly higher DIP deficits, hospitalization costs, and diagnostic test and procedure costs compared to the comparator group, with p < 0.05 reported for all comparisons. Length of stay was also longer in the infected group, achieving statistical significance at p < 0.05. Additionally, MDRO type count positively correlated with hospitalization costs, diagnostic test and procedure costs, length of stay, and DIP deficits, where p < 0.05. Surgical site wound contamination grade similarly showed positive correlation with hospitalization costs, diagnostic test and procedure costs, length of stay, and DIP deficits, with p < 0.05.

Safety data regarding adverse events, serious adverse events, discontinuations, and tolerability were not reported. The study limitations section was empty. Funding or conflicts of interest were not reported. Practice relevance was not reported. Causality and certainty notes were not reported.

Clinicians should interpret these findings cautiously given the observational nature of the retrospective cohort study. Absolute numbers and effect sizes were not reported, limiting the assessment of clinical magnitude. The lack of sample size and follow-up details further constrains generalizability to other settings.