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Openness-based psychoeducational booklet improved SGRQ activities in chronic respiratory disease patients during inpatient pulmonary rehabilitationOpenness booklet improved activity scores in pulmonary rehab patients

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Key Takeaway
Note that an openness-based booklet improved SGRQ activities but not total scores in inpatient PR.

A randomized controlled trial involving 136 participants diagnosed with chronic respiratory disease was conducted in an inpatient pulmonary rehabilitation setting. The study evaluated the effect of an openness-based psychoeducational booklet compared to a neutral booklet on health-related quality of life. Outcomes were measured using the St. George's Respiratory Questionnaire (SGRQ) at the completion of the rehabilitation program.

The primary outcome, SGRQ total score, showed no significant difference between the intervention and control groups. However, exploratory analysis of secondary outcomes revealed that the intervention group exhibited significantly greater improvement in the SGRQ activities sub-dimension compared to the control group (p < .05; partial eta-squared = 0.04). No significant differences were reported for the SGRQ symptoms or impact sub-dimensions.

Safety and tolerability data were not reported in the study, and adverse events, discontinuations, or serious adverse events were not documented. The study authors noted that exploratory analyses indicated the effect on the activities sub-dimension was not moderated by participants' level of openness.

Limitations include the lack of reported effect sizes for the primary outcome and the absence of data regarding safety or tolerability. Although the practice relevance highlights potential benefits for the activities sub-dimension, the lack of total score improvement and unreported safety data necessitate cautious interpretation of these findings.

Researchers conducted a randomized controlled trial involving 136 participants diagnosed with chronic respiratory disease who were in inpatient pulmonary rehabilitation. The study compared a personality-based psychoeducational booklet aligned with openness characteristics against a neutral booklet. The primary goal was to see if the openness-focused material improved health-related quality of life.

The main finding showed that the intervention group exhibited significantly greater improvement in the activities sub-dimension of health-related quality of life compared to the control group. This specific sub-dimension measures how much the condition affects daily activities. However, the study found no significant difference between the groups for the total health-related quality of life score.

No safety concerns were reported, and no adverse events or discontinuations occurred during the study. The researchers noted that exploratory analyses showed the effect was not moderated by the participants' level of openness. Readers should understand that while activity scores improved, the overall quality of life did not change significantly. This highlights that an openness-based intervention can improve a specific sub-dimension but may not broadly change overall health outcomes.

What this means for you:
Openness booklet improved activity scores but not total quality of life in rehab patients.

Study Details

Study typeRct
Sample sizen = 136
EvidenceLevel 2
PublishedApr 2026
View Original Abstract ↓
OBJECTIVES: Five-Factor Model personality traits differ in their associations with health outcomes after therapeutic interventions. In the specific context of inpatient pulmonary rehabilitation (PR), higher levels of openness to experience have been associated with greater risk of non-response in terms of health-related quality of life. This study aimed to examine the effect of psychoeducational information aligned with characteristics associated with higher levels of openness on health-related quality of life in inpatient PR. METHODS: A single-blind multicenter randomized controlled trial was conducted in the context of inpatient PR with 136 participants diagnosed with chronic respiratory disease. Participants in the intervention group received an openness-based psychoeducational booklet, while the control group received a neutral booklet. Health-related quality of life was measured at baseline and at PR completion using the St George's Respiratory Questionnaire (SGRQ), which includes a total score and three sub-dimensions (i.e., symptoms, activities, impact). Mixed ANOVA was conducted to investigate group differences in changes in health-related quality of life. RESULTS: While no significant difference in SGRQ total score was found between the groups, the intervention group exhibited significantly greater improvement in the SGRQ "activities" sub-dimension compared to the control group (ηₚ = 0.04, p < .05). Exploratory analyses showed that this effect was not moderated by participants' level of openness. CONCLUSIONS: This study highlights that an openness-based intervention can improve a sub-dimension of health-related quality of life in inpatient PR and offers valuable insights for the conception of future personality-based interventions in PR.
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