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Openness-based psychoeducational booklet improved SGRQ activities in chronic respiratory disease patients during inpatient pulmonary rehabilitation.

Openness-based psychoeducational booklet improved SGRQ activities in chronic respiratory disease pat…
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Key Takeaway
Note that an openness-based booklet improved SGRQ activities but not total scores in inpatient PR.

A randomized controlled trial involving 136 participants diagnosed with chronic respiratory disease was conducted in an inpatient pulmonary rehabilitation setting. The study evaluated the effect of an openness-based psychoeducational booklet compared to a neutral booklet on health-related quality of life. Outcomes were measured using the St. George's Respiratory Questionnaire (SGRQ) at the completion of the rehabilitation program.

The primary outcome, SGRQ total score, showed no significant difference between the intervention and control groups. However, exploratory analysis of secondary outcomes revealed that the intervention group exhibited significantly greater improvement in the SGRQ activities sub-dimension compared to the control group (p < .05; partial eta-squared = 0.04). No significant differences were reported for the SGRQ symptoms or impact sub-dimensions.

Safety and tolerability data were not reported in the study, and adverse events, discontinuations, or serious adverse events were not documented. The study authors noted that exploratory analyses indicated the effect on the activities sub-dimension was not moderated by participants' level of openness.

Limitations include the lack of reported effect sizes for the primary outcome and the absence of data regarding safety or tolerability. Although the practice relevance highlights potential benefits for the activities sub-dimension, the lack of total score improvement and unreported safety data necessitate cautious interpretation of these findings.

Study Details

Study typeRct
Sample sizen = 136
EvidenceLevel 2
PublishedApr 2026
View Original Abstract ↓
OBJECTIVES: Five-Factor Model personality traits differ in their associations with health outcomes after therapeutic interventions. In the specific context of inpatient pulmonary rehabilitation (PR), higher levels of openness to experience have been associated with greater risk of non-response in terms of health-related quality of life. This study aimed to examine the effect of psychoeducational information aligned with characteristics associated with higher levels of openness on health-related quality of life in inpatient PR. METHODS: A single-blind multicenter randomized controlled trial was conducted in the context of inpatient PR with 136 participants diagnosed with chronic respiratory disease. Participants in the intervention group received an openness-based psychoeducational booklet, while the control group received a neutral booklet. Health-related quality of life was measured at baseline and at PR completion using the St George's Respiratory Questionnaire (SGRQ), which includes a total score and three sub-dimensions (i.e., symptoms, activities, impact). Mixed ANOVA was conducted to investigate group differences in changes in health-related quality of life. RESULTS: While no significant difference in SGRQ total score was found between the groups, the intervention group exhibited significantly greater improvement in the SGRQ "activities" sub-dimension compared to the control group (ηₚ = 0.04, p < .05). Exploratory analyses showed that this effect was not moderated by participants' level of openness. CONCLUSIONS: This study highlights that an openness-based intervention can improve a sub-dimension of health-related quality of life in inpatient PR and offers valuable insights for the conception of future personality-based interventions in PR.
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