This single-blind randomized controlled trial enrolled 84 adults undergoing elective coronary artery bypass grafting at a tertiary cardiac surgery center in Shiraz, Iran, with 80 participants completing the 30-day follow-up. The intervention group received a three-phase nurse-led smartphone program with pre-operative education, in-hospital monitoring, and 30-day post-discharge follow-up via weekly calls and messaging, while the control group received standard care with one handout.
For pain outcomes, the intervention group showed significantly lower scores both in-hospital (3.96 ± 0.42 vs. 4.29 ± 0.35, p < 0.001, d = -0.85) and post-discharge (1.45 ± 0.38 vs. 2.01 ± 0.50, p < 0.001, d = -1.26). Post-discharge blood pressure and heart rate were also reduced in the intervention group, with significant group-by-time interactions (p < 0.05). However, total quality of life scores at 30 days showed no significant between-group difference (adjusted mean difference = 0.15, 95% CI -1.27 to 1.57, p = 0.832), though the pain domain of quality of life improved significantly in the intervention group (p = 0.002).
Safety data were not reported, and 4 participants discontinued from the original 84 randomized. Key limitations include the single-center design in Iran, small sample size, and lack of primary outcome reporting. The intervention appears easily integrated into nursing practice and may support recovery in resource-limited settings, but these findings should be interpreted cautiously until replicated in more diverse populations with longer follow-up.
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BACKGROUND: Patients after coronary artery bypass grafting often face suboptimal recovery, including pain, reduced quality of life, and haemodynamic instability, worsened by limited self-care knowledge and inadequate post-discharge support. Nurse-led smartphone-based interventions may offer a scalable solution for resource-limited settings.
OBJECTIVE: To evaluate the effects of a nurse-led, smartphone-based educational and follow-up intervention on pain, quality of life, and haemodynamic stability in patients undergoing elective coronary artery bypass grafting.
DESIGN: Single-blind, randomized controlled trial.
SETTINGS: A tertiary cardiac surgery center in Shiraz, Iran, from July 2024 to April 2025.
PARTICIPANTS: Eighty-four adults undergoing elective coronary artery bypass grafting, randomized (1:1) to intervention or control groups, with 80 completing the study (40 per group).
METHODS: The intervention group received a three-phase programme: (1) pre-operative education via videos, messages, and a face-to-face session; (2) in-hospital education and daily symptom monitoring for pain and self-care; (3) 30-day post-discharge follow-up with weekly nurse-led calls and real-time messaging. Controls received standard care with one handout. Outcomes included pain (visual analog scale), quality of life (SF-36 Health Survey), and hemodynamic indices (blood pressure, heart rate). Pain and haemodynamic indices were assessed at baseline, three times daily for four days in the general ward following post-intensive care unit discharge (12 time points), and weekly post-discharge (days 7, 14, 21, 30; 4 time points), totaling 17 assessments. Quality of life was assessed at baseline and 30 days post-discharge. Data were analyzed using Mann-Whitney U tests, t-tests, and repeated-measures analysis of variance.
RESULTS: The intervention group had lower pain scores (in-hospital: 3.96 ± 0.42 vs. 4.29 ± 0.35, p < 0.001, d = -0.85, 95% CI -0.50 to -0.16; post-discharge: 1.45 ± 0.38 vs. 2.01 ± 0.50, p < 0.001, d = -1.26, 95% CI -0.76 to -0.36) and reduced post-discharge blood pressure and heart rate. Total quality of life scores showed no significant between-group differences at 30 days (adjusted ANCOVA: adjusted mean difference = 0.15, 95% CI -1.27 to 1.57, p = 0.832), while the pain domain improved significantly in the intervention group (p = 0.002, r = -0.35). Group-by-time interactions were significant for pain and haemodynamic outcomes (p < 0.05).
CONCLUSIONS: This nurse-led, smartphone-based intervention reduced pain, improved pain-related quality of life, and stabilized haemodynamic parameters post-coronary artery bypass grafting. Easily integrated into nursing practice, it supports recovery in resource-limited settings and merits further study.
REGISTRATION: Registered at the Iranian Registry of Clinical Trials, IRCT20240426061574N1, registered June 05, 2024, https://irct.behdasht.gov.ir/search/result?query=IRCT20240426061574N1.
SOCIAL MEDIA ABSTRACT: Nurse-led smartphone intervention reduces pain and stabilizes haemodynamics in post-coronary artery bypass grafting patients over 30 days.