Mode
Text Size
Log in / Sign up

One Health diagnostics improve pathogen detection and outbreak prediction through cross-sector collaboration and technological innovationOne Health approach could stop future pandemics before they start

AI-generated summary of the cited source, checked by automated accuracy review. How we work

Key Takeaway
Note that cross-sectoral collaboration and technological integration are essential for improving zoonotic disease detection.

This structured narrative review synthesizes the role of One Health diagnostics in managing zoonotic diseases such as SARS, Ebola, Hendra virus, and COVID-19. The scope includes evaluating cross-sector collaboration, capacity building, and technological innovations to enhance surveillance and outbreak prediction.

The authors argue that effective detection relies on coordinated efforts between veterinary, public health, and environmental sectors supported by international organizations. Integration of technologies including PCR, NGS, metagenomics, AI, GIS, mHealth, biosensors, and point-of-care testing are identified as key drivers for real-time monitoring and improved field diagnostics.

Several barriers to implementation were identified, including inadequate adherence to standardized data-sharing principles, fragmented surveillance systems, and limited infrastructure in low-resource settings. The authors also note insufficient interdisciplinary integration as a significant hurdle. These findings suggest that while technological advancements offer substantial potential for outbreak prediction, systemic improvements in governance and sustainable investment are required to overcome existing structural limitations.

How this fits prior evidence

This narrative review addresses gaps in current surveillance by highlighting the necessity of cross-sectoral collaboration and technology integration. It builds upon prior evidence regarding EBOV-specific gene signatures as a research tool and modeling of Ebola epidemic dynamics by emphasizing that integrated One Health systems are required to move from research tools to practical, large-scale outbreak management.

Imagine a world where the next SARS or Ebola is caught before it spreads. That's the promise of the One Health approach, which connects veterinarians, doctors, and environmental scientists to track diseases at their source. A new review of existing research explains how this cross-sector teamwork, backed by tools like PCR tests, AI, and mobile health apps, can spot pathogens faster and predict outbreaks.

The review looked at how countries have used One Health diagnostics for diseases like Hendra virus and COVID-19. It found that when veterinary, public health, and environmental groups share data and work together, they can detect threats earlier and respond more effectively. Technologies like genomic sequencing and real-time monitoring have made field diagnostics quicker and more accurate.

But the review also highlights big challenges. Many countries still have fragmented surveillance systems, limited resources in low-income areas, and poor data sharing. Without standardized rules and sustained investment, the full potential of One Health remains out of reach.

This isn't a clinical trial with hard numbers. It's a summary of case studies and expert opinions. Still, it offers a clear roadmap: if we want to prevent the next pandemic, we need to break down silos and invest in connected health systems now.

What this means for you:
Catching diseases at the animal-human-environment crossroads could stop outbreaks early.

Common questions

What is the One Health approach?

One Health is a way of working that brings together experts in human health, animal health, and the environment. The idea is that diseases often jump between animals and people, so monitoring all three areas can help catch outbreaks early. This review says it relies on coordinated efforts among veterinary, public health, and environmental sectors.

What diseases does this approach help with?

The review looked at zoonotic diseases, which are infections that spread from animals to humans. Examples include SARS, Ebola, Hendra virus, and COVID-19. By tracking these diseases in animals and the environment, health officials may be able to spot them before they cause widespread illness in people.

What technologies are used in One Health diagnostics?

The review mentions several tools that have improved disease detection. These include PCR tests, next-generation sequencing (NGS), metagenomics, artificial intelligence (AI), geographic information systems (GIS), mobile health (mHealth), biosensors, and point-of-care testing. These technologies help with real-time monitoring, field diagnostics, and outbreak prediction.

What are the main barriers to using One Health?

The review points to several challenges. These include inadequate adherence to standardized data-sharing principles, fragmented surveillance systems, limited infrastructure in low-resource settings, and insufficient interdisciplinary integration. In other words, different groups don't always share information well, and poorer areas lack the tools and training needed.

Is this review based on new clinical trial data?

No. This is a narrative review, which means it summarizes existing literature and case studies. It does not provide primary clinical trial data or direct evidence of causality. So while it offers useful insights, the findings are based on what other researchers have already reported, not on a new experiment.

Study Details

Study typeSystematic review
EvidenceLevel 1
PublishedJul 2026
View Original Abstract ↓
Zoonotic diseases at the human–animal–environment interface pose an increasing global health threat, necessitating integrated diagnostic strategies under the One Health framework. This structured narrative review synthesizes evidence linking One Health diagnostics to cross-sectoral collaboration, diagnostic capacity strengthening, data sharing, preparedness, and emerging technological innovations. Predefined search terms were used to conduct a targeted literature search in Google Scholar, PubMed, and Web of Science (WOS) to identify relevant literature on One Health diagnostics, zoonotic disease surveillance, pathogen detection, diagnostic preparedness, laboratory systems, governance, and emerging technologies. Studies considered eligible were research articles, reviews, case studies, policy documents, technical reports, and organizational guidelines published in English between 2010 and 2026. The literature was reviewed and summarized thematically across the following domains: laboratory systems for veterinary and public health, integrated surveillance, low-resource settings, technological innovation, data interoperability, and diagnostic preparedness. The findings indicate that effective One Health diagnostics rely on coordinated efforts among the veterinary, public health, and environmental sectors, supported by international organizations and integrated surveillance systems. Technological advancements, including polymerase chain reaction, next-generation sequencing, metagenomics, artificial intelligence, geographic information systems, mobile health tools, biosensors, and point-of-care testing, have improved pathogen detection, real-time monitoring, field diagnostics, and outbreak prediction. However, major challenges persist, including inadequate adherence to standardized data-sharing principles, fragmented surveillance systems, limited infrastructure in low-resource settings, and insufficient interdisciplinary integration. Case studies of SARS, Ebola, Hendra virus, and COVID-19 demonstrate the practical benefits of collaborative approaches while also highlighting systemic barriers to implementation. This review highlights the need for improvements in governance, standardized data-sharing frameworks, sustainable investment in diagnostic capacity, and better integration of new technologies into surveillance systems. Adopting a One Health approach to diagnostics research will require coordination to achieve meaningful impact through policy innovation, global collaboration, laboratory strengthening, and enhanced capacity for the detection, response, and prevention of zoonotic and emerging infectious diseases.
Free Newsletter

Clinical research that matters. Delivered to your inbox.

Join thousands of clinicians and researchers. No spam, unsubscribe anytime.