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Online CBT reduces dental anxiety more effectively in patients with low baseline pain sensitivityOnline CBT eases dental fear, but pain sensitivity matters

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Key Takeaway
Note that online CBT for dental anxiety is significantly more effective for patients with low baseline pain sensitivity.

This randomized controlled trial enrolled 499 participants with high dental anxiety at a dental school clinic. The study compared an online cognitive-behavioral therapy (CBT) intervention against a time- and attention-matched control group. Participants were assessed on the Modified Dental Anxiety Scale (MDAS) and the Pain Sensitivity Index (PSI).

Baseline pain sensitivity showed no significant difference between the intervention group (Mean=67.4, SD=22.3; n=329) and the control group (Mean=67.6, SD=24.2; n=170; p = 0.92). However, a statistical interaction was observed: baseline pain sensitivity significantly moderated the effect of the online CBT intervention (F(1, 633) = 5.91; p = 0.015). Specifically, participants with low pain sensitivity were significantly more likely to experience reductions in dental anxiety compared to those with high pain sensitivity.

Safety data and tolerability were not reported. The findings suggest that the efficacy of online CBT for dental anxiety may be influenced by a patient's baseline pain sensitivity. Patients identified with high pain sensitivity may require more targeted interventions or higher intervention doses to achieve adequate reduction in dental anxiety.

If the thought of a dental drill makes your heart race, you're not alone. Dental anxiety is common, and it can keep people from getting the care they need. A new study tested whether an online cognitive-behavioral therapy (CBT) program could help. CBT is a type of talk therapy that helps you change negative thoughts and behaviors. The results are promising, but they come with an important twist: how sensitive you are to pain may determine how well it works.

The study included 499 adults with high dental anxiety, recruited from a dental school clinic in the northeastern United States. They were randomly assigned to either an online CBT program or a control intervention that matched the time and attention. The researchers measured dental anxiety using a standard scale at the start, then again at 1 and 3 months after the program.

Overall, the online CBT helped reduce dental anxiety. But the key finding was that baseline pain sensitivity, measured with a simple questionnaire, changed the picture. People with low pain sensitivity were significantly more likely to see their dental anxiety drop after CBT. Those with high pain sensitivity did not benefit as much. The difference was statistically significant, meaning it's unlikely to be due to chance.

This doesn't mean online CBT is useless for people with high pain sensitivity. It suggests they might need a different approach or a more intensive program. The study is a randomized controlled trial, which is a strong design, but the pain sensitivity finding is a statistical interaction, so it needs confirmation in future research. If you struggle with dental anxiety, talk to your dentist or a mental health professional about what options might work best for you.

What this means for you:
Online CBT helps dental anxiety, but people with high pain sensitivity may need extra support.

Common questions

What is online CBT for dental anxiety?

Online CBT is a therapy you do over the internet. It helps you change negative thoughts and behaviors about dental visits. In this study, people with high dental anxiety used an online CBT program. It was found to reduce dental anxiety, but mainly for those with low pain sensitivity.

Who did this study include?

The study included 499 adults with high dental anxiety. They were recruited from a dental school clinic in the northeastern United States. Participants were randomly assigned to either the online CBT program or a control group that received similar time and attention.

How was pain sensitivity measured?

Pain sensitivity was measured using the Pain Sensitivity Index (PSI), a questionnaire that asks about your typical reactions to pain. In this study, people with low pain sensitivity were more likely to benefit from online CBT for dental anxiety than those with high pain sensitivity.

Does this mean online CBT doesn't work for people with high pain sensitivity?

Not necessarily. The study found that people with high pain sensitivity did not see as much improvement in dental anxiety from online CBT. This might mean they need a different approach or a more intensive program. Talk to your dentist or a mental health professional about what options might be best for you.

Study Details

Study typeRct
Sample sizen = 499
EvidenceLevel 2
Follow-up3.0 mo
PublishedAug 2026
View Original Abstract ↓
Pain sensitivity is considered a stable characteristic that can influence the development of situational fears. It has been related to dental anxiety and expectation of pain before dental procedures. The objective of this analysis was to examine whether baseline pain sensitivity moderated the efficacy of an online cognitive-behavioral therapy (CBT) intervention for dental anxiety relative to an active control condition. Participants with high dental anxiety were recruited from a dental school clinic in the northeastern United States to participate in a randomized controlled trial. Patients were randomized to receive an online CBT intervention or a time- and attention-matched control intervention. Changes in dental anxiety were assessed using the Modified Dental Anxiety Scale (MDAS). Baseline pain sensitivity was measured by the Pain Sensitivity Index (PSI), which assesses the fearful appraisal of pain and expected consequences of pain. Participants completed questionnaires at baseline, and at 1- and 3-month follow ups. Linear mixed-effects model analyses using mean-centered interaction terms examined whether baseline levels of pain sensitivity moderated the treatment effect on dental anxiety. A total of 499 participants (70.6% female, 62% Black, Mean age = 49) were enrolled in the clinical trial and randomized to the CBT intervention (n = 329) or control condition (n = 170). Baseline pain sensitivity ratings between intervention group (Mean = 67.4, SD = 22.3) and control group (Mean = 67.6, SD = 24.2 did not significantly differ (t = - 0.10, p = 0.92). Baseline pain sensitivity significantly moderated the effect of the online CBT intervention on dental anxiety, such that participants with low pain sensitivity were significantly more likely to see reductions in dental anxiety when compared to those with high pain sensitivity, (F(1, 633) = 5.91, p = 0.015). Participants with lower pain sensitivity experienced the greatest benefit in terms of reduction in dental anxiety following an online CBT intervention. Individuals with high pain sensitivity may require more targeted interventions or higher intervention dose to achieve adequate reduction in dental anxiety.
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