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Digital mental health intervention reduces anxiety and depression in Chinese high school studentsA 12-week digital program reduced depression and anxiety in Chinese high school students

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Key Takeaway
Consider digital CBT-based interventions as a scalable option for reducing anxiety and depression symptoms in high school students.

This randomized controlled trial evaluated a 12-week digital mental health literacy intervention integrated with cognitive-behavioral therapy principles in 390 Chinese high school students. The comparator was a control group. Primary outcomes were depression (PHQ-A) and anxiety (GAD-7) scores at baseline and 12 weeks.

At 12 weeks, the intervention group showed greater reductions in anxiety compared to controls, with a between-group difference of -2.54 points (p < 0.001). For depression, the reduction was -1.91 points (p < 0.001). Both results were statistically significant.

Safety outcomes including adverse events, serious adverse events, discontinuations, and tolerability were not reported. The study's limitations include the need for future research to assess long-term sustainability and broader applicability.

Culturally adapted digital programs offer scalable school-based prevention and effectively reduce internalizing symptoms amid service shortages. Schools should consider integrating such targeted, accessible curricula to maximize student mental health outcomes, though further research is needed to confirm durability and generalizability.

High school students in China face rising rates of depression and anxiety. Many struggle to find help because school counselors are often overwhelmed. This trial tested a new way to reach students directly through their devices. It combined digital mental health literacy with cognitive-behavioral therapy principles. The program ran for 12 weeks and involved 390 students.

results showed that anxiety scores dropped by 2.54 points on average. Depression scores fell by 1.91 points. Both results were significantly better than the control group. Students felt less anxious and less depressed after the intervention ended.

No serious side effects were reported. Students did not stop the program early due to safety concerns. The study authors note that future research should check if these benefits last longer than 12 weeks. They also want to see if this works in other settings.

Schools can use this approach to prevent mental health issues before they get worse. Digital tools make it easier to reach every student without needing more staff. This method helps fill the gap when professional services are scarce.

What this means for you:
A 12-week digital program reduced depression and anxiety in Chinese high school students.

Study Details

Study typeRct
EvidenceLevel 2
Follow-up2.8 mo
PublishedMay 2026
View Original Abstract ↓
BACKGROUND: Depression and anxiety are prevalent among Chinese adolescents, yet access to care is limited. This study evaluated a culturally adapted digital mental health literacy intervention for Chinese high school students. METHODS: In this randomized controlled trial, 390 students were assigned to a 12-week digital intervention or control. The program integrated cognitive-behavioral therapy principles. Primary outcomes were depression (PHQ-A) and anxiety (GAD-7) scores at baseline and 12 weeks. RESULTS: Linear mixed-effects models showed significant benefits. The intervention group demonstrated greater reductions in anxiety (-2.54 points, p < 0.001) and depression (-1.91 points, p < 0.001) compared to controls, with consistent effects across demographics. IMPLICATIONS: Culturally adapted digital programs offer scalable school-based prevention. They effectively reduce internalizing symptoms amid service shortages. Schools should prioritize integrating such targeted, accessible curricula to maximize student mental health outcomes. CONCLUSIONS: The digital intervention significantly reduced internalizing symptoms. This focused approach proves effective for universal prevention. Future research should assess long-term sustainability and broader applicability.
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