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Digital mental health intervention reduces anxiety and depression in Chinese high school students

Digital mental health intervention reduces anxiety and depression in Chinese high school students
Photo by Cht Gsml / Unsplash
Key Takeaway
Consider digital CBT-based interventions as a scalable option for reducing anxiety and depression symptoms in high school students.

This randomized controlled trial evaluated a 12-week digital mental health literacy intervention integrated with cognitive-behavioral therapy principles in 390 Chinese high school students. The comparator was a control group. Primary outcomes were depression (PHQ-A) and anxiety (GAD-7) scores at baseline and 12 weeks.

At 12 weeks, the intervention group showed greater reductions in anxiety compared to controls, with a between-group difference of -2.54 points (p < 0.001). For depression, the reduction was -1.91 points (p < 0.001). Both results were statistically significant.

Safety outcomes including adverse events, serious adverse events, discontinuations, and tolerability were not reported. The study's limitations include the need for future research to assess long-term sustainability and broader applicability.

Culturally adapted digital programs offer scalable school-based prevention and effectively reduce internalizing symptoms amid service shortages. Schools should consider integrating such targeted, accessible curricula to maximize student mental health outcomes, though further research is needed to confirm durability and generalizability.

Study Details

Study typeRct
EvidenceLevel 2
Follow-up2.8 mo
PublishedMay 2026
View Original Abstract ↓
BACKGROUND: Depression and anxiety are prevalent among Chinese adolescents, yet access to care is limited. This study evaluated a culturally adapted digital mental health literacy intervention for Chinese high school students. METHODS: In this randomized controlled trial, 390 students were assigned to a 12-week digital intervention or control. The program integrated cognitive-behavioral therapy principles. Primary outcomes were depression (PHQ-A) and anxiety (GAD-7) scores at baseline and 12 weeks. RESULTS: Linear mixed-effects models showed significant benefits. The intervention group demonstrated greater reductions in anxiety (-2.54 points, p < 0.001) and depression (-1.91 points, p < 0.001) compared to controls, with consistent effects across demographics. IMPLICATIONS: Culturally adapted digital programs offer scalable school-based prevention. They effectively reduce internalizing symptoms amid service shortages. Schools should prioritize integrating such targeted, accessible curricula to maximize student mental health outcomes. CONCLUSIONS: The digital intervention significantly reduced internalizing symptoms. This focused approach proves effective for universal prevention. Future research should assess long-term sustainability and broader applicability.
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