Combination TACE plus systemic therapy showed no PFS benefit but improved OS in BCLC-C HCC patients compared to TACE alone
Combination therapy improves survival for advanced liver cancer patients in one study
This retrospective cohort study evaluated 142 patients with intermediate or advanced-stage hepatocellular carcinoma at Hunan Provincial Peop…
Combination therapy may extend life for advanced liver cancer patients, but results vary by disease stage and need more research.
Meta-analysis finds childhood asthma linked to higher risk of obstructive sleep apnea
Meta-analysis links childhood asthma to higher risk of sleep apnea
This meta-analysis of studies from the United States, Europe, and Asia found a significant association between childhood asthma and obstruct…
A large review finds children with asthma have a significantly higher risk of obstructive sleep apnea, especially in America and Asia.
Global MS burden in women of childbearing age rises 48% from 1990 to 2021
Multiple sclerosis rates rose sharply in women of childbearing age from 1990 to 2021
A global cohort analysis of 204 countries found that multiple sclerosis incidence in women aged 15–49 rose 48% from 1990 to 2021, with preva…
Multiple sclerosis cases and deaths increased among women of childbearing age globally, though disability years dropped slightly.
Modified prednisone regimen shows short-term ineffectiveness in infantile epileptic spasms syndrome based on retrospective cohort data
Blood marker may predict prednisone response in infantile spasms
This retrospective cohort study evaluated 66 IESS patients and 53 age-matched healthy controls.
A blood protein called HMGB1 may help doctors quickly tell if prednisone will work for infantile spasms.
Bayesian network meta-analysis compares exercise modalities for systemic inflammation in postmenopausal women
Resistance training reduces inflammation in postmenopausal women
This Bayesian network meta-analysis of 39 RCTs evaluated the comparative efficacy of aerobic, resistance, HIIT, and combined training on inf…
New evidence suggests different types of exercise target different inflammatory markers in postmenopausal women with obesity.
Meta-analysis shows exercise interventions impact TNF-alpha but not IL-6 or CRP in older adults
Exercise may lower specific inflammation markers in older adults
This meta-analysis of randomized controlled trials evaluated the effect of exercise interventions on serum inflammatory biomarker levels in …
New evidence shows that exercise interventions can significantly reduce certain inflammatory markers in older adults facing frailty or sarco…
Meta-analysis compares infection rates of teclistamab in clinical trials and real-world evidence
Teclistamab linked to higher infection rates in some patients
This meta-analysis of 714 patients evaluates the incidence of infections in relapsed/refractory multiple myeloma treated with teclistamab.
New data shows that patients using teclistamab for multiple myeloma may face a significant risk of developing various types of infections.
Case report and literature review of severe adverse reactions following pucotenlimab treatment
New drug treatment linked to severe neurological reactions
This case report and literature review describes severe adverse reactions following treatment with pucotenlimab in a patient with advanced b…
A single patient facing advanced breast cancer experienced life-threatening neurological symptoms after receiving the drug pucotenlimab.
Inactivated SARS-CoV-2 vaccine dosing schedules and antibody responses in adults aged 60 to 80 years
Older adults get better protection with the right vaccine booster timing
This prospective cohort study of 450 adults aged 60 to 80 years in China examined three inactivated SARS-CoV-2 vaccine dosing schedules.
New data shows older adults get the best protection when they receive specific vaccine boosters at the right time.
Systematic review identifies dual role of NLRP3 inflammasome in sepsis induced immune dysregulation
NLRP3 activation plays a dual role in sepsis
This systematic review examines the role of NLRP3 inflammasome activation and modulation in sepsis.
A review of research shows that a specific protein complex helps drive both inflammation and immune suppression during sepsis.
Th17/Treg ratios and cytokine levels associated with infection risk after kidney transplantation
Immune cell levels may predict kidney transplant infection risk
This cohort study of 200 kidney transplant recipients examined the relationship between Th17/Treg cells and cytokine levels with post-surgic…
Certain immune cell patterns and protein levels could help doctors predict which kidney transplant recipients are most at risk for infection…
Systematic review and meta-analysis of stem cell therapy for dry eye in Sjögren's syndrome
Stem Cell Therapy Eases Dry Eye in Sjögren’s Syndrome Patients
This systematic review and meta-analysis evaluated stem cell therapy for patients with dry eye syndrome caused by Sjögren's syndrome.
New analysis shows stem cell therapy eases dry eye pain and improves tear flow for people with Sjögren’s syndrome.