Higher pan-immune-inflammation value linked to worse outcomes after PCI for ACS
High inflammation scores predict worse heart outcomes in patients with acute coronary syndrome
This systematic review and meta-analysis of 18,715 adults with acute coronary syndrome undergoing PCI found that higher pan-immune-inflammat…
A new analysis shows higher inflammation markers predict death and heart failure in adults with acute coronary syndrome undergoing heart pro…
Immunotherapy and metabolic-targeted drug combination shows promise for osteosarcoma treatment
Combining immunotherapy with metabolic drugs may help treat osteosarcoma better
This narrative review explores combining immunotherapy with metabolic-targeted drugs for osteosarcoma, focusing on metabolic reprogramming i…
Doctors are looking at mixing immune system treatments with drugs that change how cells use energy. This new approach could help fight back …
1 514 781 patients shows methylisothiazolinone allergy prevalence is 5.48% in dermatitis cases
Large review shows contact allergy to isothiazolinones affects many dermatitis patients
This systematic review and meta-analysis examined contact allergy prevalence to isothiazolinones in 1 514 781 dermatitis patients from 2000 …
A massive review of over 1.5 million patients found that contact allergy to isothiazolinones is common in dermatitis cases, with methylisoth…
Tumor occurrence was 25% in patients with anti-mGluR5 autoimmune encephalitis, higher in Western than Chinese patients
Tumors appear in one quarter of patients with this rare brain inflammation
This systematic review and analysis examined 60 patients with anti-mGluR5 autoimmune encephalitis. The authors compared MRI-negative versus …
A review of 60 patients found tumors in 25 percent of cases, with rates much higher in Western regions than in China.
Modulation of neutrophil function and death in critically ill patients with sepsis is discussed in this narrative review
Review discusses neutrophil modulation in sepsis for critically ill patients
This narrative review discusses modulation of neutrophil function and death in critically ill patients with sepsis. The authors synthesize c…
This narrative review explores how changing neutrophil function might affect sepsis outcomes in critically ill patients, though no specific …
scFv-based biologics show potential for immunomodulation in type 1 and type 2 diabetes
Review explores scFv biologics for Type 1 and Type 2 diabetes care
This narrative review explores the potential of single-chain variable fragment (scFv)-based biologics for treating type 1 and type 2 diabete…
This review looks at scFv-based biologics for diabetes. It discusses how these treatments might help with immune control and blood sugar bal…
Periodontitis and chronic liver disease linked through proposed oral-gut-liver axis
Conceptual framework links liver, gut, immune, and oral health
This narrative review proposes a Liver-Gut-Immune-Oral Axis linking periodontitis and chronic liver disease. The authors synthesize mechanis…
A narrative review suggests a conceptual link between liver disease and oral health, though this biological system needs direct experimental…
Biologic and targeted synthetic DMARDs show reassuring malignancy safety in inflammatory arthritides, but non-melanoma skin cancer risk rises with TNF inhibitors
Biologics for arthritis: Cancer risk appears low overall
This narrative review of biologic and targeted synthetic DMARDs in immune-mediated inflammatory arthritides finds most therapies have reassu…
Most biologic arthritis drugs don't raise overall cancer risk, but skin cancer risk may be higher with some.
Ultrasound-driven mechanical immunomodulation shows promise for tumor therapy but faces key hurdles
Early review finds ultrasound may help tumors but safety needs more study
This narrative review examines ultrasound-driven mechanical immunomodulation as a tumor therapy. The authors synthesize evidence that mechan…
A new review suggests ultrasound-driven mechanical immunomodulation could affect tumors, though dosimetry standardization and targeting accu…
Narrative review discusses cerebral small vessel disease without reporting specific interventions or outcomes
Narrative review offers perspective on cerebral small vessel disease
This narrative review addresses cerebral small vessel disease but does not report specific interventions, comparators, or outcomes. The auth…
A narrative review discusses cerebral small vessel disease without reporting new clinical data or specific treatment outcomes.
Combining immunoglobulins and cytokine levels could predict allergen-specific immunotherapy effectiveness
Biological markers may help predict allergen immunotherapy success
This narrative review examines predicting the effectiveness of allergen-specific immunotherapy (AIT) for allergic diseases. The authors sugg…
A review suggests combining immunoglobulins and cytokine levels could predict allergen immunotherapy effectiveness and guide therapy for all…
Chemo-immunotherapy yields 12-month disease-free status in rare triple-negative neuroendocrine breast cancer
A single patient remains disease-free after a new chemo-immunotherapy approach for rare breast cancer
This case report describes a 71-year-old woman with triple-negative neuroendocrine breast cancer treated with paclitaxel, cisplatin, and pem…
A 71-year-old woman with rare breast cancer stayed disease-free for a year using a combination of chemotherapy and immunotherapy that doctor…