Ven-Chi-Dec Regimen Induces Remission in Refractory Hodgkin Lymphoma
Venetoclax combo shows promise for relapsed Hodgkin lymphoma
A 26-year-old with relapsed/refractory classical Hodgkin lymphoma achieved complete metabolic remission after 6 cycles of venetoclax, chidam…
A 26-year-old man with relapsed Hodgkin lymphoma achieved complete remission after a novel three-drug regimen, with no significant side effe…
Narrative review of Europe-licensed anti-asthmatic biologics for severe pediatric asthma notes limited pediatric evidence
Kids' Asthma Biologics Work Differently Than Adults Think
This narrative review examines the use of Europe-licensed anti-asthmatic biologics in pediatric patients with severe asthma. The authors hig…
• Biologics help severe childhood asthma but act unlike adult treatments • Young patients unresponsive to standard inhalers or steroids bene…
Bayesian network meta-analysis of first-line immunotherapy versus TKI for advanced hepatocellular carcinoma
Immunotherapy Outperforms Standard Care for Advanced Liver Cancer
This Bayesian network meta-analysis of 7,301 patients with advanced hepatocellular carcinoma synthesized evidence from randomized trials. It…
A new analysis of 10 clinical trials shows that immunotherapy drugs help people with advanced liver cancer live longer than standard treatme…
Narrative review discusses cellular immunotherapy strategies for cholangiocarcinoma with noted limitations
New CAR T Cell Strategy May Beat Tough Liver Cancer
This narrative review examines cellular immunotherapy approaches for cholangiocarcinoma, including CAR-based therapies, multi-antigen design…
A new plan to fight bile duct cancer combines advanced cell therapy with other drugs to break through tumor defenses.
Review of methionine manipulation in solid tumor immunotherapy settings
Doctors explore changing methionine levels to help immune cells fight solid tumors better
This narrative review examines the role of therapeutic manipulation of methionine availability, GCN2 signaling, and reactive oxygen species …
This review looks at how changing methionine availability might help immune cells work harder against solid tumors. It focuses on specific s…
Systematic review and meta-analysis of adherence to intranasal corticosteroids and oral antihistamines in adults with allergic rhinitis
Most People With Allergies Skip Their Meds, New Data Shows
This systematic review and meta-analysis evaluated adherence to intranasal corticosteroids and oral antihistamines among 191,103 adults with…
If you have hay fever and sometimes skip your allergy spray or pill, you are far from alone: a new analysis of nearly 200,000 patients finds…
Review of Chinese yam polysaccharides highlights safety gaps and need for further research
Chinese yam polysaccharides may boost immune balance through specific chemical structures
This narrative review examines Chinese yam polysaccharides (CYPs) as potential immunomodulatory agents. The authors note significant limitat…
New research shows how specific sugars in Chinese yam talk to your immune system to balance inflammation and fight infection
Systematic review and meta-analysis on cold air bronchial challenge test for asthma diagnosis
Cold air test may cut asthma misdiagnosis in half
This systematic review and meta-analysis of 39 studies evaluated the diagnostic accuracy of the cold air bronchial challenge test for asthma…
A cold air breathing test may help doctors spot asthma more accurately, especially when symptoms show up during exercise.
Case report and review: azacytidine plus ruxolitinib in connective tissue disease with CMML and myelofibrosis
A single patient found relief from blood cancer with a new drug combo
This case report and literature review describes a 52-year-old male with connective tissue disease, chronic myelomonocytic leukemia, and mye…
One man with blood cancer saw his fever and anemia improve after two years on a specific drug mix, offering a glimpse into potential new tre…
Review reframes COPD therapy toward integrated death program modulation by inflammatory endotype
New research links cell death types to COPD inflammatory patterns
This review synthesizes mechanistic associations between cell death pathways and COPD inflammatory endotypes. The authors describe preferent…
This review suggests specific cell death pathways may help explain how different COPD types respond to treatments like dupilumab.
Narrative Review Explores Post-Stroke Immunosuppression in Ischemic Stroke
Stroke survivors face a hidden immune trap that invites deadly infections
This narrative review examines post-stroke immunosuppression in patients with ischemic stroke. The authors synthesize current understanding …
A stroke causes a hidden immune shutdown that leaves patients dangerously vulnerable to infections like pneumonia, and new research explains…
Review highlights translational potential of beta-blockers and neurotrophin inhibitors in cancer treatment
Cancer nerves talk to immune cells and block treatment success
This review discusses the potential of beta-adrenergic blockers and neurotrophin signaling inhibitors in cancer therapy. The authors note th…
Cancer cells talk to nerves to hide from the immune system, but new drugs might stop this secret conversation before it starts.