Pilot study reports 60.0% conversion rate with lenvatinib, envafolimab, and TACE in hepatocellular carcinoma
New Liver Cancer Combo Makes Surgery Possible for More Patients
This prospective pilot study enrolled 15 patients with Barcelona Clinic Liver Cancer stage B or C unresectable hepatocellular carcinoma.
This new treatment plan turns advanced liver cancer into operable disease for many patients.
Ruxolitinib plus photopheresis shows promise for steroid-refractory chronic graft-versus-host disease
New Hope for Stubborn Transplant Complication
A retrospective analysis compared ruxolitinib plus extracorporeal photopheresis versus photopheresis alone in patients with steroid-refracto…
This combo may help patients reduce or stop steroid use — a major win for quality of life.
Review of tissue-resident memory T cell features in cancer and autoimmune diseases
New Immune Cells Could Flip Cancer and Autoimmune Treatment
This narrative review examines the developmental differentiation and molecular features of tissue-resident memory T cells within the tumor…
The same immune cells that help fight cancer tumors can also drive autoimmune disease damage, offering a new way to treat both conditions.
Narrative review explores cytoskeleton-mediated autophagy regulation in neurodegeneration and aging
Review suggests cytoskeleton-autophagy axis may help treat neurodegeneration and aging
This narrative review examines the role of cytoskeleton-mediated autophagy regulation in the contexts of neurodegeneration and aging.
Targeting the cell's structural framework and cleanup system could offer new ways to treat neurodegeneration and aging.
First Report of Vedolizumab-Associated Recall Urticaria in a Case Report and Literature Review
Why Hives Return to Old Injection Spots
This case report and literature review describes the first documented instance of vedolizumab-associated recall urticaria in a 25-year-old m…
A new case report reveals a rare skin reaction where hives return strictly to past injection sites.
Phase 1 trial shows ESAT6-MPT64 skin test safe with high sensitivity for active TB
New TB Skin Test Shows Promise in Early Human Trial
A Phase 1 randomized clinical trial in 60 participants (30 healthy controls, 30 active TB patients) found the recombinant ESAT6-MPT64 skin t…
A new skin test for tuberculosis proved safe and accurately identified active cases in the first human trial, offering a simpler, cheaper al…
Single-center retrospective study associates ferritin and eosinophil levels with acute asthma exacerbation in children
High Iron Levels Signal Worse Asthma Attacks in Kids
This single-center retrospective study examined 120 children with asthma to identify markers associated with acute exacerbation.
Checking iron levels alongside standard asthma markers could help doctors predict dangerous flare-ups sooner.
Benralizumab reduces asthma exacerbations in severe eosinophilic asthma patients over 24 weeks
New Asthma Shot May Cut Severe Attacks to Zero
This prospective, single-arm, multicenter, phase IV study evaluated benralizumab in 138 benralizumab-naïve adults (18–75 years) with severe …
A new injection appears safe and effective at reducing severe asthma attacks in adults.
Imiquimod TLR7 stimulation shows sex-specific immune responses in HIV and non-HIV populations
Research shows immune reactions to imiquimod vary between men and women with HIV
This cohort study evaluated TLR7 stimulation with imiquimod in 1,326 individuals living with HIV and 43 people without HIV.
Women with HIV show different immune reactions to imiquimod than men, suggesting doctors may need to consider biological sex when developing…
Baseline vitamin D deficiency occurred in 73.08% of TAO patients receiving IVGC therapy with calcium supplementation
Simple Blood Test Could Predict Thyroid Eye Treatment Success
This retrospective cohort study evaluated 52 thyroid-associated ophthalmopathy patients treated with intravenous glucocorticoids and standar…
Checking vitamin D levels could help doctors choose the best treatment for thyroid eye disease.
Retrospective cohort suggests romiplostim reduces platelet engraftment time in plasma cell neoplasms
New Drug Cuts Recovery Time After Stem Cell Transplant for Blood Cancer
This retrospective cohort study included 15 patients receiving romiplostim and 21 historical controls undergoing autologous stem cell transp…
A new drug helps blood cancer patients recover from stem cell transplants two days faster, reducing hospital stays and costs.
FDA Approves Dupixent (dupilumab) for Allergic Fungal Rhinosinusitis in Patients with History of Sino-Nasal Surgery
FDA approves Dupixent for treating allergic fungal sinus infections in patients who have had sinus surgery
Dupixent (dupilumab) has been approved for the treatment of adult and pediatric patients aged 6 years and older with allergic fungal rhinosi…
FDA approves Dupixent for allergic fungal sinus infections in adults and children aged 6 and older who have had sinus surgery.