Same-day desensitization linked to lower breakthrough reaction rate than rapid protocol in chemotherapy hypersensitivity
Can a same-day approach reduce allergic reactions during cancer treatment?
A retrospective cohort study of 120 patients with hypersensitivity reactions to platinum- or taxane-based chemotherapy compared same-day des…
A same-day desensitization approach reduced breakthrough allergic reactions to 15% compared to 24% for patients receiving rapid protocols du…
Plasma GPX activity negatively correlates with non-EoE atopic disease in pediatric subjects only
Early study finds link between blood enzyme and childhood allergies, but not EoE
An exploratory study in pediatric and adult subjects found plasma glutathione peroxidase (GPX) activity negatively correlated with non-EoE a…
Lower blood enzyme levels linked to childhood allergies, but not eosinophilic esophagitis, in an early study.
Dietary zinc supplementation alleviates allergic rhinitis in rats via gut-nasal axis
Could zinc help with allergies? A rat study suggests a possible gut-nose connection.
A preclinical animal study in rats found dietary zinc supplementation may alleviate allergic rhinitis, especially at 150 ppm, through mechan…
A rat study suggests zinc supplements might help seasonal allergies by balancing gut bacteria and reducing inflammation in the nose.
Asia-Pacific experts propose clinical remission definition and lung function goals for severe asthma
What does it mean to beat severe asthma in Asia? Experts propose new goals.
A position statement by Asia-Pacific experts reviewed severe asthma management challenges in the region. They proposed a clinical remission …
Experts redefine severe asthma success in Asia by prioritizing symptom control and stability over impossible lung function recovery.
Systematic review suggests biologics may improve outcomes in chronic rhinosinusitis with nasal polyps
Can newer biologic drugs help people with chronic sinus polyps breathe easier?
A systematic review of clinical trials and real-world data in patients with chronic rhinosinusitis with nasal polyps found biologics may enh…
Newer biologic drugs can improve quality of life for chronic sinus polyps patients, reduce steroid use, and lower the need for sinus surgery…
EUFOREA summit sets priorities for allergy and respiratory care research and advocacy
What should doctors prioritize for allergy and asthma care? Experts just met to decide.
A summit report outlines research, educational, and advocacy priorities for managing chronic inflammatory respiratory conditions. The report…
Medical experts just aligned on a coordinated plan to improve care for chronic allergies, asthma, and sinus problems over the next two years…
Protocol published for network meta-analysis of first-line treatments in advanced hepatocellular carcinoma
Researchers plan future analysis of first-line liver cancer treatments
This is a protocol for an individual patient data network meta-analysis comparing all first-line regimens for advanced hepatocellular carcin…
A new plan will compare all first-line liver cancer treatments to find which offer the best survival and fewest serious side effects by Marc…
Systematic review links PPARγ to atopic dermatitis pathogenesis and identifies it as a potential therapeutic target.
Review suggests a protein target may be linked to eczema and could lead to new treatments
A systematic review synthesizes mechanistic evidence linking peroxisome proliferator-activated receptor gamma (PPARγ) to atopic dermatitis p…
A protein called PPARγ could be a key target for new eczema treatments, as it helps restore skin barrier function and regulate immune respon…
FDA Approves Children's Zyrtec Allergy (cetirizine) for Symptoms of Upper Respiratory Allergies
FDA approves a chewable allergy medicine for children called Children's Zyrtec Allergy.
The FDA approved Children's Zyrtec Allergy (cetirizine) for temporarily relieving symptoms of hay fever or other upper respiratory allergies…
FDA approves chewable allergy medicine for kids as young as 2 to help with runny nose, sneezing, and itchy eyes from hay fever.
Qualitative study reveals six themes of patient experience with post-COVID-19 olfactory dysfunction
What's it really like to lose your sense of smell after COVID?
A qualitative study of 20 patients with post-COVID-19 olfactory dysfunction from a Danish otolaryngology department identified six themes de…
Losing the smell of coffee or a child's hair after COVID feels like an invisible disability that changes how people eat, socialize, and see …
Review suggests chemokine inhibition as prospective therapeutic target for atopic dermatitis
Review suggests chemokine pathways may be promising targets for eczema treatment
A review of basic and clinical research in patients with AD and AD model mice found that chemokine ligand-receptor interactions regulate imm…
Blocking specific immune signals in eczema skin reduced inflammation in mice, suggesting a new treatment path as human trials progress.
Allergen-antibody complexes activate human neutrophils via FcγR-independent phagocytosis in lab study
Lab study explores how immune cells react to pollen allergen complexes
A laboratory study using neutrophils from birch pollen allergic and non-allergic donors found that allergen-antibody immune complexes (AICs)…
Lab tests show modified pollen complexes help immune cells present allergens better, while standard versions trigger DNA webs that might blo…