Case report and review of primary cervical melanoma shows inconsistent response to PD-1/PD-L1 inhibitors
Rare cervical melanoma cases show mixed results with immunotherapy and surgery
A case report of two patients with primary malignant melanoma of the cervix and a review of nine reported cases treated with PD-1/PD-L1 inhi…
Surgery alone fails for rare cervical melanoma, as 80% of patients progress on immunotherapy without chemotherapy or radiation.
Mepolizumab fails to improve refractory chronic cough in small eosinophilic airways disease trial
Mepolizumab reduced inflammation but did not improve cough in a small study
A single-centre randomised controlled trial of 30 patients with refractory chronic cough and eosinophilic airways disease found subcutaneous…
Mepolizumab lowered inflammation markers in patients with chronic cough but failed to reduce their coughing or improve their quality of life…
Asthma associated with increased odds of venous thromboembolism, pulmonary embolism, and deep vein thrombosis in observational studies
Asthma Linked to Higher Risk of Blood Clots in Observational Data
This meta-analysis of observational studies involving patients with asthma found a statistically significant association between asthma and …
People with asthma face a 1.61 times higher risk of blood clots, with the danger of pulmonary embolism rising 2.41 times and deep vein throm…
House dust mite immunotherapy reduces IgE and symptoms in Indonesian children with allergic rhinitis and asthma
Could weekly dust mite shots help Indonesian children breathe easier with less medicine?
A small RCT of 41 Indonesian children with allergic rhinitis and asthma found 14 weeks of weekly subcutaneous HDM immunotherapy significantl…
Weekly dust mite shots helped Indonesian children with allergies and asthma breathe easier, needing fewer pills and feeling less discomfort …
Fermentation enhances finger millet and soybean nutritional value and functional properties in functional foods
Review finds fermentation improves nutritional value of finger millet and soybean
This systematic review analyzed 59 peer-reviewed studies on the fermentation of finger millet and soybean globally.
Fermenting finger millet and soybean boosts nutrient absorption, reduces compounds that block vitamins, and improves taste and shelf life fo…
Engineering antibody-armed oncolytic viruses may enhance tumor-specific delivery and immune effects
Can viruses carry antibodies right to tumors to fight cancer better?
A systematic review examines strategies for engineering oncolytic viruses to express therapeutic antibodies within tumors.
Engineered viruses could carry cancer-fighting antibodies directly to tumors, boosting drug levels where needed while sparing healthy organs…
Tumor-associated neutrophils regulate PDAC progression via TGF-β and CXCR2 pathways
Can stopping white blood cells help stop pancreatic cancer from growing?
This systematic review examined tumor-associated neutrophils (TANs) in patients with pancreatic ductal adenocarcinoma (PDAC).
White blood cells that shield pancreatic cancer from treatment can be reprogrammed to fight the disease instead of fueling its growth.
Risk models for ICI-associated myocarditis occurrence and severity in patients receiving immune checkpoint inhibitors
Can blood tests and heart signals predict dangerous heart inflammation from cancer drugs?
This retrospective unmatched case-control study evaluated baseline biomarkers and combined signatures in 196 patients receiving immune check…
A mix of blood tests and heart rhythm checks can predict dangerous heart inflammation from cancer drugs with better accuracy than blood work…
Federated model adaptation improves radiation pneumonitis prediction in lung cancer patients receiving immunotherapy
Can we predict lung inflammation risk in patients getting immunotherapy?
This cohort study evaluated a federated radiomics model for predicting radiation pneumonitis in 610 lung cancer patients treated with defini…
A new model adapts to predict lung swelling risks for cancer patients receiving both radiation and immunotherapy, fixing errors in older too…
Baseline inflammation patterns in severe asthma patients receiving biologic therapy
Severe asthma patients with neutrophilic patterns had lower lung function and more sleep apnea
This retrospective observational cohort study analyzed 103 patients with severe asthma treated with biologic agents.
Severe asthma patients with neutrophilic patterns had lower lung function and more sleep apnea than those with other inflammation types.
Stapokibart shows nasal symptom reduction in pediatric seasonal allergic rhinitis case series
Could a new drug help teens breathe easier during allergy season?
A retrospective case series of 20 pediatric patients with moderate-to-severe seasonal allergic rhinitis found that all patients demonstrated…
Twenty young patients with moderate-to-severe seasonal allergic rhinitis took stapokibart for one month.
Acupuncture plus sphenopalatine ganglion needling shows higher response rate than loratadine for allergic rhinitis
Acupuncture combined with targeted needling may improve allergy symptoms better than standard medication
A 260-patient RCT in persistent moderate-to-severe allergic rhinitis found combination acupuncture and sphenopalatine ganglion needling had …
Combining acupuncture with targeted needling helped more hay fever patients find relief than standard allergy medication alone.