Respiratory virus prevalence is higher in acute asthma than stable asthma across children and adults
Your Asthma Flare-Up Might Not Be What You Think
This systematic review and meta-analysis pooled data from 111 studies involving children and adults with asthma.
A major new analysis reveals viruses are found in more than half of all asthma attacks, forcing a rethink of what a positive test really mea…
Biomarkers and functional assays evaluated for shrimp allergy in African American populations in the United States
Why a Shrimp Allergy Test Might Be Wrong—And What to Do Next
This systematic review examined molecular and environmental biomarkers, extract-based IgE testing, component-resolved diagnostics, and funct…
A common shrimp allergy test often gives false positives, especially in certain communities, meaning many people may be avoiding a food they…
Breg-related gene signature predicts survival and immune landscape in head and neck squamous cell carcinoma
Your Immune System Holds a Hidden Clue to Head and Neck Cancer Survival
This cohort study analyzed patients with head and neck squamous cell carcinoma (HNSCC) using bioinformatics data from TCGA and GEO databases…
A new eight-gene test predicts head and neck cancer survival better than standard measures, helping doctors identify which patients might be…
Case report and review of primary cervical melanoma shows inconsistent response to PD-1/PD-L1 inhibitors
Rare cervical melanoma cases show mixed results with immunotherapy and surgery
A case report of two patients with primary malignant melanoma of the cervix and a review of nine reported cases treated with PD-1/PD-L1 inhi…
Surgery alone fails for rare cervical melanoma, as 80% of patients progress on immunotherapy without chemotherapy or radiation.
Mepolizumab fails to improve refractory chronic cough in small eosinophilic airways disease trial
Mepolizumab reduced inflammation but did not improve cough in a small study
A single-centre randomised controlled trial of 30 patients with refractory chronic cough and eosinophilic airways disease found subcutaneous…
Mepolizumab lowered inflammation markers in patients with chronic cough but failed to reduce their coughing or improve their quality of life…
Asthma associated with increased odds of venous thromboembolism, pulmonary embolism, and deep vein thrombosis in observational studies
Asthma Linked to Higher Risk of Blood Clots in Observational Data
This meta-analysis of observational studies involving patients with asthma found a statistically significant association between asthma and …
People with asthma face a 1.61 times higher risk of blood clots, with the danger of pulmonary embolism rising 2.41 times and deep vein throm…
House dust mite immunotherapy reduces IgE and symptoms in Indonesian children with allergic rhinitis and asthma
Could weekly dust mite shots help Indonesian children breathe easier with less medicine?
A small RCT of 41 Indonesian children with allergic rhinitis and asthma found 14 weeks of weekly subcutaneous HDM immunotherapy significantl…
Weekly dust mite shots helped Indonesian children with allergies and asthma breathe easier, needing fewer pills and feeling less discomfort …
Fermentation enhances finger millet and soybean nutritional value and functional properties in functional foods
Review finds fermentation improves nutritional value of finger millet and soybean
This systematic review analyzed 59 peer-reviewed studies on the fermentation of finger millet and soybean globally.
Fermenting finger millet and soybean boosts nutrient absorption, reduces compounds that block vitamins, and improves taste and shelf life fo…
Engineering antibody-armed oncolytic viruses may enhance tumor-specific delivery and immune effects
Can viruses carry antibodies right to tumors to fight cancer better?
A systematic review examines strategies for engineering oncolytic viruses to express therapeutic antibodies within tumors.
Engineered viruses could carry cancer-fighting antibodies directly to tumors, boosting drug levels where needed while sparing healthy organs…
Tumor-associated neutrophils regulate PDAC progression via TGF-β and CXCR2 pathways
Can stopping white blood cells help stop pancreatic cancer from growing?
This systematic review examined tumor-associated neutrophils (TANs) in patients with pancreatic ductal adenocarcinoma (PDAC).
White blood cells that shield pancreatic cancer from treatment can be reprogrammed to fight the disease instead of fueling its growth.
Risk models for ICI-associated myocarditis occurrence and severity in patients receiving immune checkpoint inhibitors
Can blood tests and heart signals predict dangerous heart inflammation from cancer drugs?
This retrospective unmatched case-control study evaluated baseline biomarkers and combined signatures in 196 patients receiving immune check…
A mix of blood tests and heart rhythm checks can predict dangerous heart inflammation from cancer drugs with better accuracy than blood work…
Federated model adaptation improves radiation pneumonitis prediction in lung cancer patients receiving immunotherapy
Can we predict lung inflammation risk in patients getting immunotherapy?
This cohort study evaluated a federated radiomics model for predicting radiation pneumonitis in 610 lung cancer patients treated with defini…
A new model adapts to predict lung swelling risks for cancer patients receiving both radiation and immunotherapy, fixing errors in older too…