FDA Approves Sdamlo (amlodipine) for Hypertension and Coronary Artery Disease
FDA approves new blood pressure and heart drug Sdamlo for adults and children.
FDA approved Sdamlo, a calcium channel blocker, for hypertension in adults and children aged 6 years and older, and for coronary artery dise…
The FDA approved Sdamlo (amlodipine) for high blood pressure in adults and children 6 and older, and for certain types of chest pain and hea…
Meta-analysis finds SGLT2 inhibitors reduce cardiac arrest risk in CKD patients
SGLT2 Inhibitors Lower Cardiac Arrest Risk in Kidney Disease
This meta-analysis of 8 RCTs evaluated SGLT2 inhibitors versus placebo in patients with chronic kidney disease. SGLT2i significantly reduced…
A meta-analysis of 8 trials found SGLT2 inhibitors cut cardiac arrest risk by 47% in chronic kidney disease patients, though other arrhythmi…
Systematic review and meta-analysis finds no mortality benefit for alternative loop diuretics in chronic heart failure
Alternative heart failure diuretics show no mortality benefit but higher risk
This meta-analysis of 23 RCTs with 4902 patients with chronic heart failure found that alternative loop diuretics did not reduce all-cause m…
A review of 23 trials found alternative diuretics did not lower death risk in heart failure patients, but some raised safety concerns.
RAS inhibitor use after TAVI linked to lower mortality in severe aortic stenosis
Common Heart Pill May Boost Survival After Valve Replacement
This systematic review and meta-analysis of observational data from 36,015 patients with severe aortic stenosis undergoing TAVI found that u…
A common class of blood pressure pills appears to help people live longer after minimally invasive heart valve replacement, but doctors stil…
LAAC and DOACs match warfarin for stroke prevention in AF patients
LAAC and DOACs Cut Bleeding Risk Better Than Warfarin
A network meta-analysis of 78,594 AF patients found LAAC and DOACs offered similar protection against ischemic stroke as warfarin, while sig…
New research shows two new options for atrial fibrillation patients lower bleeding risks while keeping stroke protection the same as older d…
Health and Wellness coaching for blood pressure control in minor stroke or TIA
Your Daily Habits Could Shield You From Another Stroke
This is a Phase III randomized controlled trial protocol for adults with minor stroke or transient ischaemic attack in New Zealand. The stud…
• Lifestyle coaching cuts blood pressure better than standard care.
Review discusses digital twin architecture for predicting aortic disease progression versus static thresholds
Digital Twins Predict Aortic Aneurysm Growth Before It Becomes Dangerous
This review examines the potential of patient-specific digital twin architecture for managing patients with aortic disease. The authors cont…
A new digital twin model predicts how your aortic aneurysm will grow, helping doctors time treatment earlier and more precisely.
Meta-analysis shows lactated ringer's may shorten hospital stay but offers no mortality benefit in acute pancreatitis
New review shows lactated ringer fluid may shorten hospital stays for some pancreatitis patients without saving lives
This systematic review and meta-analysis evaluated fluid resuscitation strategies for patients with acute pancreatitis. The analysis compare…
A large study found that using lactated ringer fluid instead of normal saline did not lower death rates for acute pancreatitis. However, the…
SGLT-2 inhibitors reduce heart failure hospitalization and stroke in patients with acute coronary syndrome
SGLT-2 Drugs Cut Stroke Risk After Heart Attack
This meta-analysis evaluated SGLT-2 inhibitors in patients hospitalized for acute coronary syndrome with additional risk factors. The analys…
New research shows that a specific diabetes drug can lower the risk of stroke and heart failure in people recovering from a heart attack.
Review of regulatory T cell therapy in solid organ transplantation with no reported outcomes
Regulatory T cell therapy shows promise for helping patients after solid organ transplant procedures
This narrative review examines regulatory T cell therapy for solid organ transplantation. The authors note that population, sample size, and…
This review looks at how regulatory T cell therapy might help people who need new organs. More research is needed to see if it works well an…
Network meta-analysis compares glucose-lowering therapies for heart failure with reduced ejection fraction and type 2 diabetes
Sotagliflozin Cuts Heart Failure Risk By Half In High-Risk Patients
This systematic review and network meta-analysis synthesized evidence on three glucose-lowering therapies for patients with coexisting heart…
New drugs for diabetes could also save lives in people with heart failure and lower the need for hospital visits.
Systematic review on OCLN in stroke and atherosclerosis highlights regulatory controversies
Doctors are still debating if changing a specific protein can help stop stroke or heart disease problems
This systematic review synthesizes evidence on the occludin gene in ischemic stroke, atherosclerosis, and hypertensive encephalopathy. The a…
This review looked at how a protein called OCLN might affect brain and heart health. Experts say more research is needed before we know if c…