Review suggests TWEAK-Fn14 axis contributes to brain injury and cardiac dysfunction pathology
Review explores protein link between brain and heart diseases
A systematic review summarizes evidence on the TWEAK-Fn14 signaling pathway in cardio-cerebrovascular diseases.
High levels of two specific proteins linked to brain swelling and heart scarring may offer a future target for treating brain-heart syndrome…
Systematic review explores pathogenesis and emerging treatments for sepsis-induced cardiomyopathy
Review explores potential new treatments for sepsis-related heart problems
A systematic review examined the pathogenesis and treatment landscape for sepsis-induced cardiomyopathy in patients with severe sepsis.
New approaches targeting inflammation, calcium, and energy metabolism show potential for treating heart damage in severe sepsis patients.
Machine learning shows moderate accuracy for predicting AF recurrence after catheter ablation in meta-analysis
Can AI predict if your irregular heartbeat will return after treatment?
A systematic review and meta-analysis of 17 studies found machine learning algorithms achieved a mean AUC of 0.81 for predicting atrial fibr…
Artificial intelligence can predict if an irregular heartbeat will return after treatment with an average accuracy score of 0.81, though res…
PAC use in cardiogenic shock associated with lower mortality but higher sepsis risk in meta-analysis
Can a heart monitor help people survive cardiogenic shock?
A meta-analysis of 14 observational studies including 789,553 adults with cardiogenic shock found pulmonary artery catheterization (PAC) use…
A heart monitor linked to lower death rates in cardiogenic shock also raises infection risks and the need for stronger research.
Preliminary U.S. data links underlying health conditions to higher COVID-19 severity risk
Early U.S. data suggests certain health conditions may increase severe COVID-19 risk
A preliminary U.S. observational report suggests patients with COVID-19 who have underlying conditions like diabetes, cardiovascular disease…
Early U.S. data suggests people with diabetes, heart disease, lung issues, or who smoke face higher risk for severe COVID-19 requiring hospi…
Observational study finds one third of U.S. adults report hypertension, with 75% of those using medication
How many U.S. adults have high blood pressure? About one third, survey finds
An observational study of U.S. adults found approximately one third reported having hypertension, and an estimated 75% of those individuals …
About one third of U.S. adults say they have high blood pressure, and three out of four of those people report taking medication to manage i…
Higher uric acid-to-creatinine ratio linked to preeclampsia risk in advanced maternal age pregnancy
Higher uric acid ratio linked to increased preeclampsia risk in older pregnant women
A retrospective cohort study of 2,296 pregnant women aged ≥35 years found each standard deviation increase in serum uric acid-to-creatinine …
Older pregnant women with higher uric acid-to-creatinine ratios face 29% greater odds of developing preeclampsia, a serious condition affect…
Phase 2 trial of oral ifetroban in DMD cardiomyopathy reports no safety results yet
Can a new pill help protect the hearts of boys with Duchenne muscular dystrophy?
A phase 2 randomized, double-blind, placebo-controlled trial evaluated low- and high-dose oral ifetroban in 46 males with DMD-associated car…
A new pill called ifetroban is being tested to safely treat heart weakness in boys with Duchenne muscular dystrophy, addressing a leading ca…
Pulsed field ablation shows similar efficacy to radiofrequency ablation for paroxysmal AF
Is pulsed field ablation better for AFib? New study finds it matches standard treatment
A multicenter RCT of 289 patients with drug-resistant paroxysmal AF found no significant difference in 12-month single-procedure success bet…
A new heart procedure for AFib works as well as the standard, with 77% of patients free from recurrence after a year and fewer serious event…
Topical milrinone or nitroglycerin studied for internal mammary artery flow in CABG patients
Small study tests topical drugs on artery grafts during heart bypass surgery
A phase 3 randomized trial in 46 patients undergoing elective CABG compared topical milrinone, nitroglycerin, or normal saline applied to th…
A small study tested topical drugs on artery grafts during heart bypass surgery, measuring blood flow changes in 46 patients over just 12 mi…
Systematic review outlines role of mitochondrial DNA mutations in heart failure pathogenesis
Review explores how mitochondrial DNA mutations may contribute to heart failure
A systematic review summarizes evidence on mitochondrial DNA mutations in heart failure.
Mitochondrial DNA mutations can cause heart failure by disrupting energy production, increasing harmful molecules, and triggering inflammati…
Million Hearts program shows high hypertension control possible in high-risk populations
Can clinics with high-risk patients still control blood pressure well?
An unspecified study of the Million Hearts Hypertension Control Champions program across various healthcare settings found achieving high hy…
Clinics serving high-risk patients can still achieve high blood pressure control rates, proving the goal is within reach even in difficult h…