Systematic review finds no progestogen class effect in oral contraception, with varying safety profiles
A Safer Pill? How a New Generation of Birth Control May Lower Your Risk
A systematic review of oral contraception in women found no class effect among progestogens.
New birth control pills using natural estrogens may lower blood clot risks compared to older versions, offering a safer option for millions …
Systematic review links neutrophil extracellular trap dysregulation to pregnancy complications
Web of White Blood Cells Linked to Pregnancy Risks
A systematic review of emerging evidence indicates that dysregulation of neutrophil extracellular trap (NET) formation and clearance is stro…
A sticky web of white blood cells meant to fight germs can instead trigger serious pregnancy risks like preeclampsia and preterm birth when …
Overweight status at diagnosis in Kuwaiti children with new-onset type 1 diabetes is associated with milder clinical presentation and lower HbA1c
Overweight Kids With Diabetes Have Milder Symptoms
This retrospective cohort study analyzed 1,265 children aged 14 years or younger newly diagnosed with type 1 diabetes in Kuwait.
Being overweight changes how type 1 diabetes starts in children, making the early stage look different and easier to manage initially.
Metabolic profiles differ in memory T cells between TB progressors and non-progressors in Brazilian cohort
Your Immune System’s Hidden Fuel Source May Decide a TB Infection’s Fate
A proof-of-concept cohort study in Brazil examined immunometabolic profiles of Mtb-specific memory CD4+ T cells in individuals with remote l…
A specific cellular fuel source in memory immune cells may determine whether a person's tuberculosis infection stays silent or turns active.
Surgical twin reduction associated with higher adverse outcomes compared to vanishing twin syndrome in a retrospective cohort
A Vanishing Twin May Be Safer Than a Doctor's Help
This retrospective cohort study evaluated 1,796 patients diagnosed with multifetal pregnancy reduction (MFPR) or vanishing twin syndrome (VT…
When a twin pregnancy naturally reduces to one, the remaining baby may have a better chance than if doctors perform the same reduction.
SARS-CoV-2 Omicron BA.2 infection associated with persistent hormonal changes and symptom resolution in young male students
Your Hormones After COVID: A Two-Year Journey Reveals Surprising Shifts
This prospective cohort study followed 71 young male university students for 24 months after SARS-CoV-2 Omicron BA.2 infection.
While testosterone stays steady two years after Omicron infection, other key hormones in young men take a longer, complex journey to find th…
Higher BUN/Cr ratio linked to increased mortality in older patients with sepsis-associated AKI
A Simple Blood Test Ratio Could Predict Survival in Severe Infections
A retrospective cohort study of 764 patients aged ≥50 years with sepsis-associated AKI found each 1-unit increase in BUN/Cr ratio was associ…
A simple blood test ratio linked to kidney failure in severe infections now helps doctors predict which patients face higher survival risks.
Oral denatonium acetate (ARD-101) reduced weight versus placebo in adults with obesity over 28 days
Could a Bitter Pill Trick Your Gut Into Feeling Full?
Randomized, placebo-controlled clinical studies and preclinical mouse studies evaluated oral denatonium acetate (ARD-101) in adults with obe…
A new gut-targeted pill tricks your intestines into feeling full, reducing hunger and helping adults lose weight in early human trials.
In male osteoporosis, anabolic therapies improved lumbar spine and hip BMD more than antiresorptives at 12 months
Men Get Osteoporosis Too — and Now We Know Which Drugs Win
This Bayesian network meta-analysis evaluated antiresorptive and anabolic pharmacological interventions in men with osteoporosis.
A new analysis of 18 clinical trials finds that bone-building drugs may outperform bone-preserving drugs for men with osteoporosis, especial…
Pressure-controlled volume-guaranteed ventilation improved diaphragmatic function and reduced weakness in diabetic patients undergoing laparoscopic colorectal surgery
New Ventilation Mode Helps Diaphragm in Diabetics
This randomized controlled trial enrolled 80 patients with Type 2 diabetes scheduled for elective laparoscopic colorectal surgery.
A new ventilation mode protects diaphragm strength in diabetic patients after surgery, reducing breathing complications compared to standard…
Secukinumab improves cutaneous adipose tissue inflammatory signatures in psoriasis patients
Fat Under Your Skin Fuels Psoriasis Inflammation
This randomized placebo-controlled trial evaluated secukinumab in 82 patients with psoriasis.
Your body fat is not just storing energy; it is actively making your psoriasis worse, and new treatments are finally targeting this hidden f…
Macrophage glycolysis interactions modulate inflammation and polarization in sepsis
A Hidden Switch in Your Immune System Could Change Sepsis Treatment
This systematic review examined mechanisms linking macrophage glycolysis and inflammation in sepsis.
Understanding this biological energy switch gives researchers a clear new target to stop sepsis in its tracks.