FDA Approves Dapagliflozin for Heart Failure Risk Reduction and Glycemic Control in Type 2 Diabetes
FDA approves a diabetes drug that also helps protect the heart from failure
The FDA has approved dapagliflozin to reduce the risk of hospitalization for heart failure in adults with type 2 diabetes and established ca…
FDA approves a diabetes pill that lowers blood sugar and reduces heart failure hospitalization for adults with type 2 diabetes and heart ris…
FDA Approves Dapagliflozin Tablets (dapagliflozin) to Reduce Heart Failure Hospitalization Risk in Adults with Type 2 Diabetes
FDA approves a diabetes drug that also helps protect the heart
The FDA has approved dapagliflozin tablets to reduce the risk of hospitalization for heart failure in adults with type 2 diabetes mellitus a…
A new diabetes drug now protects the heart by lowering hospitalization risks for adults with type 2 diabetes and existing heart disease.
Produce Prescription Program Shows No Benefit for Cardiometabolic Outcomes in Food-Insecure Diabetes Patients
Produce prescription program did not improve health outcomes for patients with diabetes facing food insecurity
A randomized clinical trial of 2,155 patients with diabetes at risk for food insecurity found that a 12-month produce prescription program p…
A produce prescription program failed to improve health outcomes for patients with diabetes facing food insecurity in a major study.
BP variability and pulse pressure associated with cognitive decline in type 2 diabetes patients
Blood pressure swings linked to thinking problems in people with type 2 diabetes
A secondary analysis of 9,586 patients with type 2 diabetes from the ADVANCE trial found that higher blood pressure variability and baseline…
For people with type 2 diabetes, big swings in blood pressure are linked to a higher risk of memory and thinking problems down the road.
Oral quadruple therapy reduces HbA more than metformin uptitration in type 2 diabetes on triple therapy
When three diabetes pills aren't enough, does adding a fourth help more than increasing metformin?
A 24-week, multicenter RCT in 193 adults with type 2 diabetes (HbA 7.0-9.0%) on triple oral therapy compared adding a fourth oral agent vers…
When three diabetes pills fail to control blood sugar, adding a fourth medication lowered HbA1c better than simply increasing the metformin …
Calorie restriction plus exercise reduced IL-6 and knee pain more than diet alone in knee OA
Small study finds adding exercise to calorie restriction may reduce knee pain and inflammation
A 4-week RCT in 23 overweight/obese adults with knee osteoarthritis compared calorie restriction alone to restriction plus aerobic exercise.
Adding exercise to a calorie-reduced diet lowered knee pain and a specific inflammation marker in overweight people with knee osteoarthritis…
Subgroup analysis finds tirzepatide superior to dulaglutide for HbA1c and weight in type 2 diabetes
For people struggling with diabetes on dulaglutide, could switching drugs help?
This subgroup analysis of a phase IV RCT examined adults with type 2 diabetes inadequately controlled on dulaglutide.
Switching from dulaglutide to tirzepatide led to greater drops in blood sugar and body weight for adults with type 2 diabetes after 40 weeks…
App-supported resistance training linked to lean mass and bone gains in youth with type 1 diabetes
App-guided resistance training linked to muscle and bone gains in youth with type 1 diabetes
A 24-week RCT in 62 children and adolescents with type 1 diabetes found a progressive resistance training program delivered via the Diactive…
A smartphone app guiding resistance training helped youth with type 1 diabetes gain more lean muscle and bone mass than usual care over six …
Tadalafil reduces some plasma neurodegeneration biomarkers in type 2 diabetes patients
Small study finds tadalafil may lower some Alzheimer's biomarkers in diabetes patients
A post-hoc analysis of a 6-week RCT in 15 individuals with type 2 diabetes found tadalafil reduced plasma amyloid-β 40, amyloid-β 42, and gl…
A small study suggests tadalafil lowers certain Alzheimer's-related blood markers in people with type 2 diabetes, though it did not change o…
Liraglutide reduces OSA severity in patients with COPD and obesity in exploratory analysis
Could a weight loss drug help people with COPD breathe easier at night?
A secondary exploratory analysis of a 40-week RCT in 40 patients with COPD and overweight/obesity found liraglutide (3.0 mg) significantly r…
A weight loss drug reduced breathing pauses and oxygen drops for people with COPD and sleep apnea, improving general health while day-time s…
GAHT in transgender men shows no significant BMD changes but increases muscle strength and body composition
Does hormone therapy affect bone health and strength for transgender men?
A systematic review with meta-analysis of transgender men found gender affirming hormone treatment was not associated with significant longi…
After four years of gender-affirming hormone therapy, transgender men show no bone loss at key sites while gaining muscle strength and lean …
Phase II RCT: Amiloride reduces arterial stiffness and blood pressure in adults with obesity and metabolic syndrome
Low-dose amiloride reduced arterial stiffness and blood pressure in adults with obesity
A phase II, single-center RCT of 137 adults with overweight/obesity and metabolic syndrome features found 24 weeks of low-dose amiloride (5 …
Low-dose amiloride reduced arterial stiffness and blood pressure in adults with obesity, offering a potential new tool to improve heart heal…