Guideline on severe pediatric obesity with MC4R variant and puberty management
Two siblings with severe obesity and early puberty found to have genetic changes affecting their growth and health over fourteen years
This guideline, based on a case report of two Chinese siblings with a heterozygous MC4R variant, synthesizes long-term management of monogen…
Two Chinese brothers with severe obesity and early puberty received special treatments for fourteen years. Their puberty slowed down, blood …
CPAP Most Effective for Apnea-Hypopnea Index, GLP-1 RAs Improve Weight in OSA
CPAP and weight-loss drugs show different benefits for sleep apnea patients
This network meta-analysis of 3964 adults with obstructive sleep apnea found that CPAP produced the largest reduction in apnea-hypopnea inde…
A large analysis found CPAP best for breathing control, while weight-loss drugs improved body weight and blood sugar levels in sleep apnea p…
Ecnoglutide Reduces HbA1c and Body Weight in Type 2 Diabetes: Meta-Analysis
New diabetes drug cuts sugar and weight in adults with Type 2 Diabetes
A meta-analysis of 1643 adults with type 2 diabetes found that ecnoglutide significantly reduced HbA1c (MD -0.44, 95% CI -0.55 to -0.33) and…
A large review shows ecnoglutide lowers blood sugar and body weight in adults with Type 2 Diabetes. It also has an acceptable safety profile…
SMS Text Messaging Lifestyle Programs Show No Significant Benefit for Prediabetes
SMS lifestyle programs show no clear benefit for prediabetes outcomes in this meta-analysis
This systematic review and meta-analysis of 4632 adults with prediabetes found that SMS text messaging-delivered lifestyle programs did not …
A large review of text message health programs found no significant improvement in weight or diabetes risk for adults with prediabetes.
Fasting plasma glucose shows higher diagnostic accuracy than HbA1c for undiagnosed diabetes in adults
Fasting glucose outperforms HbA1c for Type 2 Diabetes diagnosis in adults
This systematic review and meta-analysis evaluated diagnostic performance in 276,203 adults without previously diagnosed diabetes.
A massive analysis of over 276,000 adults suggests fasting glucose is a more reliable diagnostic marker than HbA1c for Type 2 Diabetes.
Reversion of Prediabetes to Normoglycemia Linked to 68% Lower Diabetes Risk
Reversing prediabetes cuts diabetes risk by 68 percent in a massive study
A meta-analysis of 535,066 participants with prediabetes found that reversion to normoglycemia was associated with a 68% lower risk of incid…
Reversing prediabetes to normal blood sugar levels lowers the risk of developing diabetes by 68 percent in people with the condition.
Intensive lifestyle intervention improves health-related quality of life in patients with obesity
Greater weight loss linked to better quality of life in obesity patients
This randomized controlled trial enrolled 803 patients with obesity across eighteen primary care clinics.
A large trial shows that losing more weight is associated with better quality of life, though some racial differences were noted.
Acupuncture and moxibustion cake may reduce thyroid antibodies in Hashimoto thyroiditis
Acupuncture May Lower Thyroid Antibodies in Hashimoto Patients
A meta-analysis suggests acupuncture and moxibustion cake may lower thyroid antibodies in Hashimoto thyroiditis, but evidence is limited.
Acupuncture and moxibustion may lower thyroid antibodies in Hashimoto patients, but the evidence is still early and limited.
Systematic review and meta-analysis links Mediterranean diet to improved cardiometabolic markers
Mediterranean-style eating lowers key blood sugar and heart risk markers in adults at risk
This systematic review and meta-analysis of 1337 adults at increased risk for type 2 diabetes and cardiovascular disease found that Mediterr…
A large review of studies shows Mediterranean-style eating lowers blood sugar and cholesterol markers in adults at risk for diabetes and hea…
Systematic review and meta-analysis finds elevated magnetic sphincter augmentation erosion after sleeve gastrectomy
Magnetic sphincter augmentation erosion risk is higher after sleeve gastrectomy
This systematic review and meta-analysis of 287 patients found that magnetic sphincter augmentation (MSA) erosion after laparoscopic sleeve …
A meta-analysis shows patients with sleeve gastrectomy have a higher erosion rate after magnetic sphincter augmentation compared to nonbaria…
Meta-analysis: Postoperative oral antibiotics reduce cellulitis after cesarean in obese women
Adding two antibiotics may lower cellulitis risk for obese women having C-sections
This systematic review and meta-analysis of 1144 obese women undergoing cesarean delivery found that adding postoperative oral cephalexin an…
A large review found adding oral cephalexin and metronidazole to standard care significantly reduced cellulitis in obese women after C-secti…
Oral Sodium Butyrate Reduces Weight in Overweight Adults Without Diabetes
Oral sodium butyrate helps overweight adults without diabetes lose weight
This 12-week proof-of-concept RCT in 46 overweight adults (23 with type 2 diabetes) found that oral sodium butyrate 1875 mg/day led to great…
A new trial shows oral sodium butyrate helps adults without diabetes lose more weight than a placebo over three months.