Systematic review of saponins for type 2 diabetes and its complications
Saponins Show New Promise for Type 2 Diabetes and Complications
This systematic review summarizes the antidiabetic effects of saponins in type 2 diabetes. Saponins modulate key signaling pathways and show…
New research shows plant compounds called saponins may help manage type 2 diabetes and protect organs from related damage.
Systematic review links psycho-emotional and environmental factors to eating behaviors in adults with overweight or obesity
Young adults eat to cope with stress, not just hunger
This systematic review synthesizes evidence from 7,614 participants regarding factors associated with eating behaviors in young and middle-a…
Doctors now know that stress and emotions drive eating habits in young adults, so treating the mind helps manage weight.
Narrative review examines voltage-dependent K+ channels in rodent and human studies
New Potassium Channels Could Change How We Treat Diabetes
This narrative review synthesizes findings from rodent and human studies regarding voltage-dependent K+ channels. The authors discuss the sc…
Tiny potassium channels in the pancreas act like gatekeepers for insulin, and scientists now think targeting them could lead to smarter diab…
FDA Approves Levothyroxine Sodium Tablets for Hypothyroidism and TSH Suppression
FDA approves new thyroid hormone drug for hypothyroidism and thyroid cancer.
The FDA approved levothyroxine sodium tablets for replacement therapy in primary, secondary, and tertiary hypothyroidism, and as an adjunct …
The FDA has approved levothyroxine sodium tablets to treat hypothyroidism and as part of therapy for certain thyroid cancers. This synthetic…
Stand-alone digital lifestyle interventions show significant improvements in weight and dietary habits for adults with overweight or obesity compared to controls
Digital Tools Help Adults Lose Weight Without Human Support
A systematic review and meta-analysis of 19 studies involving 3,556 adults found that stand-alone digital lifestyle interventions significan…
New research shows that fully automated digital tools can help adults lose weight and eat better without needing a human coach or live suppo…
Pregabalin 300 or 600 mg/day significantly reduces pain in painful diabetic peripheral neuropathy versus placebo
Higher doses of pregabalin helped reduce pain scores for people with painful diabetic nerve problems compared to placebo
This randomized controlled trial enrolled 729 patients with painful diabetic peripheral neuropathy. Pregabalin doses of 300 mg/day and 600 m…
A study found that taking 300 or 600 mg of pregabalin daily lowered pain scores better than a fake pill. Lower doses did not work as well fo…
Network Meta-Analysis Finds Tirzepatide and Sleeve Gastrectomy Equally Effective for Weight Loss in Obesity
New Weight Loss Pill Matches Surgery Results Without the Scalpel
A network meta-analysis of 14,293 adults with obesity found that tirzepatide 10 or 15 mg and sleeve gastrectomy achieved similar weight loss…
A diabetes drug now pulls even with stomach surgery for weight loss offering hope to millions who dread going under the knife but it is not …
Digital Health Interventions Show Mixed Results for Cardiovascular Risk Reduction in Type 2 Diabetes Patients Across Weight Categories
Digital Health Tools Help Some Diabetes Patients But Not Others
A secondary analysis of the SMARTDiabetes trial reveals that digital health interventions failed to lower 10-year cardiovascular risk in the…
Digital health tools cut heart risk for people with diabetes who have normal weight, but not for those who are overweight or obese.
Narrative review suggests gluten-free diet may help Hashimoto's in Celiac patients but evidence is insufficient for universal use
Could Gluten Be Worsening Your Thyroid Condition Without You Knowing
This narrative review examines the role of a gluten-free diet (GFD) in patients with Celiac disease, Hashimoto's thyroiditis, or both. The a…
If you have Hashimoto's thyroiditis and feel like something is still off, gluten could be playing a hidden role in your symptoms even if you…
INSTI switching linked to higher metabolic risk in people with HIV
Switching HIV meds raises diabetes risk but not heart attack danger
A global cohort study found that switching to integrase inhibitors increased risks for obesity, diabetes, and hypertension, but not MACE, ov…
Switching HIV medication to a newer class may raise the risk of diabetes and weight gain, but it does not appear to increase the risk of hea…
Propofol-first sequence reduces hypoxemia in obese patients undergoing gastroscopy
Giving anesthesia in a new order cuts oxygen risk for obese patients
This single-center RCT compared propofol-first versus remifentanil-first sedation sequences in obese patients undergoing gastroscopy. The pr…
A new drug sequence cuts low oxygen events by nearly half in obese patients getting gastroscopy sedation.
Systematic review links gestational diabetes to higher maternal CKD risk in large cohort analysis
Gestational Diabetes May Raise Kidney Risk Years After Pregnancy
This systematic review and meta-analysis evaluated the association between gestational diabetes mellitus and maternal kidney outcomes across…
A massive new analysis of over 21 million women shows that gestational diabetes may double the risk of chronic kidney disease later in life,…