Single-dose fultagliptin benzoate pharmacokinetics and safety in patients with mild to moderate renal insufficiency versus healthy volunteers
A New Diabetes Pill That Stays Longer When Kidneys Slow
This Phase I, non-randomized, open-label, parallel-control trial evaluated the pharmacokinetics, pharmacodynamics, and safety of a single or…
A new diabetes pill builds up in the body when kidneys slow, meaning some patients with mild or moderate kidney issues may need half the usu…
In older in-patients with type 2 diabetes and cognitive impairment, CGM showed superior glucose metrics compared to point-of-care tests
The Wearable Glucose Sensor That Catches What Hospital Tests Miss
This observational study evaluated continuous glucose monitoring (CGM) versus point-of-care tests (POCT) in 30 older in-patients with type 2…
A new wearable sensor caught dangerous overnight low blood sugar in older hospitalized patients with dementia that routine hospital tests co…
Exercise training improves function in 157 patients with mitochondrial myopathy
Exercise May Strengthen Muscles Doctors Once Told to Rest
This meta-analysis and systematic review evaluated moderate-intensity aerobic and resistance exercise in 157 patients with mitochondrial myo…
For a disease once treated with rest, a careful exercise plan now looks like one of the most promising tools to rebuild strength.
Scoping review of molecular pathways in insulin resistance among women with PCOS
Your PCOS Symptoms May Start in Your Cells, Not Your Weight
This scoping review examined molecular or cellular pathways related to insulin resistance or glucose metabolism in women of reproductive age…
Women with PCOS often face insulin resistance rooted in cells, not weight, shifting treatment focus from body size to cellular signals for b…
Autologous cell therapy improved healing rates and reduced ulcer area in patients with diabetic foot ulcers compared to control
Using your own cells to heal stubborn diabetic foot wounds
This meta-analysis and systematic review evaluated autologous cell therapy versus control in 2,214 patients with diabetic foot ulcers.
Using a patient's own cells to jump-start healing may close diabetic foot ulcers that regular treatment leaves open for months.
Silver/copper nanoparticle dressing shows greater wound reduction than ionic silver in infected diabetic foot ulcers
Small pilot study finds silver-copper dressing may reduce wound size in diabetic foot ulcers
A small pilot RCT of 30 patients with infected diabetic foot ulcers compared silver/copper nanoparticle dressings to ionic silver dressings.
A new silver-copper dressing shrank infected diabetic foot ulcers by 43% in just one week, outperforming standard silver dressings in a smal…
Review of quercetin in metabolic diseases shows promise but lacks clinical validation
Review suggests quercetin may have multiple beneficial effects on metabolic conditions
This review evaluates quercetin for conditions including diabetes, obesity, and gout.
A natural compound found in fruits and vegetables shows promise for managing type 2 diabetes, obesity, and fatty liver disease, though human…
Protocol compares Mediterranean and low-carb diets for diabetes remission in Lebanese adults
Two Diets Go Head-to-Head for Type 2 Diabetes Remission
This randomized controlled trial protocol will compare a low-calorie Mediterranean-style diet to a low-calorie, low-carbohydrate diet for di…
A trial in Lebanon will test if a low-calorie Mediterranean or low-carb diet can put type 2 diabetes into remission, focusing on real-world …
Systematic review shows PCOS in obese women links to high MASLD and 2–4 fold increased cardiovascular and diabetes risks
PCOS Is Not Just About Your Ovaries Anymore
This systematic review evaluated the extra-ovarian health impacts of polycystic ovary syndrome (PCOS) in women, with a focus on those with o…
Polycystic ovary syndrome is being rethought as a full-body metabolic condition, and that shift could change how — and by whom — it's treate…
Maternal obesity linked to altered DNA methylation of iron-regulating genes in early pregnancy
A Hidden Link Between Weight and Pregnancy Iron Levels
A cross-sectional analysis of 65 pregnant women found that obesity was associated with lower TfR2 and higher HJV gene methylation at 12 week…
A mother's weight can chemically alter genes that control iron use in early pregnancy, helping explain why some expectant mothers struggle w…
Existing cognitive frailty models show good discrimination in older adults with diabetes but suffer high bias risk
Can A Simple Score Predict Memory Loss In Older Diabetics?
This systematic review and meta-analysis evaluated 2,947 diabetic patients to assess the predictive performance and risk of bias of existing…
Simple risk scores may soon flag older diabetics who are sliding toward combined memory and muscle decline — but today's tools still need wo…
Pheochromocytoma misdiagnosed as allergic vasculitis in a 36-year-old male led to ulcer healing but required toe amputation
24 Years of Leg Ulcers Led Back to a Hidden Tumor
This case report describes a 36-year-old male with pheochromocytoma initially misdiagnosed as allergic vasculitis.
A man's 24-year leg ulcer mystery ended when a hidden adrenal tumor was found, proving the wrong diagnosis kept his wounds from healing.